Sylvatic vector-borne pathogens including Cytauxzoon europaeus in the European wildcat (Felis silvestris) from southwestern Germany.
Anaplasma phagocytophilum
Bartonella taylorii
Cytauxzoon europaeus
Rickettsia helvetica
Europe
Piroplasmida
Tick-borne pathogens
Journal
Parasites & vectors
ISSN: 1756-3305
Titre abrégé: Parasit Vectors
Pays: England
ID NLM: 101462774
Informations de publication
Date de publication:
24 Aug 2024
24 Aug 2024
Historique:
received:
21
06
2024
accepted:
28
07
2024
medline:
26
8
2024
pubmed:
26
8
2024
entrez:
24
8
2024
Statut:
epublish
Résumé
European wildcats (Felis silvestris) are widely distributed in Europe and a strictly protected species in Germany. Lately, anthropogenic protective efforts lead to increasing numbers of wildcats in southwestern Germany. Moreover, in recent years the numbers of domestic cats are increasing. Thus, the contact between domestic and wildcats may lead to the spread of zoonotic pathogens in both animal species. As data on vector-borne pathogens (VBPs) in wildcats from Germany are limited to date, the objective of this study was to investigate the presence and current distribution of VBPs in wildcats from southwestern Germany. Skin and spleen samples from 117 European wildcats, originating from a regional carcass-monitoring program in southwestern Germany, were examined by real-time and conventional polymerase chain reaction (PCR) for the presence of Anaplasma phagocytophilum, Neoehrlichia mikurensis, Rickettsia spp., Bartonella spp., and Piroplasmida. In total, 6.8% (n = 8) of the wildcats were Rickettsia-positive, specified as R. helvetica. Three wildcats were positive for A. phagocytophilum (2.6%), one for Bartonella spp., namely B. taylorii (0.8%), and 84 for Cytauxzoon spp. (71.8%). Out of these 84 samples, 23 were further sequenced revealing very high identity levels (99.84-100%) to C. europaeus, which is considered to be pathogenic for domestic cats. All wildcats were negative for the presence of N. mikurensis DNA. European wildcats in southwestern Germany are hosting several VBPs. With the exception of Cytauxzoon spp., low prevalence rates of most examined pathogens suggest that wildcats are primarily incidental hosts for sylvatic pathogens associated with rodents, in contrast to domestic cats. However, the high prevalence of the cat-associated pathogen C. europaeus suggests that wildcats in southwestern Germany may serve as reservoirs for this pathogen.
Sections du résumé
BACKGROUND
BACKGROUND
European wildcats (Felis silvestris) are widely distributed in Europe and a strictly protected species in Germany. Lately, anthropogenic protective efforts lead to increasing numbers of wildcats in southwestern Germany. Moreover, in recent years the numbers of domestic cats are increasing. Thus, the contact between domestic and wildcats may lead to the spread of zoonotic pathogens in both animal species. As data on vector-borne pathogens (VBPs) in wildcats from Germany are limited to date, the objective of this study was to investigate the presence and current distribution of VBPs in wildcats from southwestern Germany.
METHODS
METHODS
Skin and spleen samples from 117 European wildcats, originating from a regional carcass-monitoring program in southwestern Germany, were examined by real-time and conventional polymerase chain reaction (PCR) for the presence of Anaplasma phagocytophilum, Neoehrlichia mikurensis, Rickettsia spp., Bartonella spp., and Piroplasmida.
RESULTS
RESULTS
In total, 6.8% (n = 8) of the wildcats were Rickettsia-positive, specified as R. helvetica. Three wildcats were positive for A. phagocytophilum (2.6%), one for Bartonella spp., namely B. taylorii (0.8%), and 84 for Cytauxzoon spp. (71.8%). Out of these 84 samples, 23 were further sequenced revealing very high identity levels (99.84-100%) to C. europaeus, which is considered to be pathogenic for domestic cats. All wildcats were negative for the presence of N. mikurensis DNA.
CONCLUSIONS
CONCLUSIONS
European wildcats in southwestern Germany are hosting several VBPs. With the exception of Cytauxzoon spp., low prevalence rates of most examined pathogens suggest that wildcats are primarily incidental hosts for sylvatic pathogens associated with rodents, in contrast to domestic cats. However, the high prevalence of the cat-associated pathogen C. europaeus suggests that wildcats in southwestern Germany may serve as reservoirs for this pathogen.
Identifiants
pubmed: 39182156
doi: 10.1186/s13071-024-06428-w
pii: 10.1186/s13071-024-06428-w
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
361Informations de copyright
© 2024. The Author(s).
Références
Kareiva P, Watts S, McDonald R, Boucher T. Domesticated nature: shaping landscapes and ecosystems for human welfare. Science. 2007;316:1866–9. https://doi.org/10.1126/science.1140170 .
doi: 10.1126/science.1140170
pubmed: 17600209
Beugin M-P, Salvador O, Leblanc G, Queney G, Natoli E, Pontier D. Hybridization between Felis silvestris silvestris and Felis silvestris catus in two contrasted environments in France. Ecol Evol. 2020;10:263–76. https://doi.org/10.1002/ece3.5892 .
doi: 10.1002/ece3.5892
pubmed: 31988727
Velli E, Caniglia R, Mattucci F. Phylogenetic history and phylogeographic patterns of the European wildcat (Felis silvestris) populations. Animals. 2023;13:953. https://doi.org/10.3390/ani13050953 .
doi: 10.3390/ani13050953
pubmed: 36899811
pmcid: 10000227
Eckert I, Suchentrunk F, Markov G, Hartl GB. Genetic diversity and integrity of German wildcat (Felis silvestris) populations as revealed by microsatellites, allozymes, and mitochondrial DNA sequences. Mamm Biol. 2010;75:160–74. https://doi.org/10.1016/j.mambio.2009.07.005 .
doi: 10.1016/j.mambio.2009.07.005
Mueller SA, Reiners TE, Steyer K, von Thaden A, Tiesmeyer A, Nowak C. Revealing the origin of wildcat reappearance after presumed long-term absence. Eur J Wildl Res. 2020;66:1–8. https://doi.org/10.1007/s10344-020-01433-7 .
doi: 10.1007/s10344-020-01433-7
Ellwanger G, Raths U, Benz A, Runge S, Ackermann W, Sachteleben J, editors. Der nationale Bericht 2019 zur FFH-Richtlinie. Ergebnisse und Bewertung der Erhaltungszustände. Teil 2 – Die Arten der Anhänge II, IV und V. 584th ed.: Bundesamt für Naturschutz; 2021.
Faure E, Kitchener AC. An archaeological and historical review of the relationships between felids and people. Anthrozoös. 2009;22:221–38. https://doi.org/10.2752/175303709X457577 .
doi: 10.2752/175303709X457577
Krajcarz M, Krajcarz MT, Baca M, Baumann C, van Neer W, Popović D, et al. Ancestors of domestic cats in Neolithic Central Europe: isotopic evidence of a synanthropic diet. Proc Natl Acad Sci USA. 2020;117:17710–9. https://doi.org/10.1073/pnas.1918884117 .
doi: 10.1073/pnas.1918884117
pubmed: 32661161
pmcid: 7395498
Nussberger B, Barbosa S, Beaumont M, Currat M, Devillard S, Heurich M, et al. A common statement on anthropogenic hybridization of the European wildcat (Felis silvestris). Front Ecol Evol. 2023;11:1156387. https://doi.org/10.3389/fevo.2023.1156387 .
doi: 10.3389/fevo.2023.1156387
ZZF. Anzahl der Haustiere in deutschen Haushalten nach Tierarten in den Jahren 2000 bis 2023 (in Millionen). 2024.
Otranto D, Cantacessi C, Pfeffer M, Dantas-Torres F, Brianti E, Deplazes P, et al. The role of wild canids and felids in spreading parasites to dogs and cats in Europe: part I: protozoa and tick-borne agents. Vet Parasitol. 2015;1–2:12–23.
doi: 10.1016/j.vetpar.2015.04.022
Dabritz HA, Conrad PA. Cats and toxoplasma: implications for public health. Zoonoses Public Health. 2010;57:34–52. https://doi.org/10.1111/j.1863-2378.2009.01273.x .
doi: 10.1111/j.1863-2378.2009.01273.x
pubmed: 19744306
Breitschwerdt EB, Kordick DL. Bartonella infection in animals: carriership, reservoir potential, pathogenicity, and zoonotic potential for human infection. Clin Microbiol Rev. 2000;13:428–38. https://doi.org/10.1128/cmr.13.3.428 .
doi: 10.1128/cmr.13.3.428
pubmed: 10885985
pmcid: 88941
Rizzoli A, Silaghi C, Obiegala A, Rudolf I, Hubálek Z, Földvári G, et al. Ixodes ricinus and its transmitted pathogens in Urban and Peri-Urban Areas in Europe: new hazards and relevance for public health. Front Public Health. 2014;2:251. https://doi.org/10.3389/fpubh.2014.00251 .
doi: 10.3389/fpubh.2014.00251
pubmed: 25520947
pmcid: 4248671
Parola P, Davoust B, Raoult D. Tick- and flea-borne rickettsial emerging zoonoses. Vet Res. 2005;36:469–92. https://doi.org/10.1051/vetres:2005004 .
doi: 10.1051/vetres:2005004
pubmed: 15845235
Reif KE, Macaluso KR. Ecology of Rickettsia felis: a review. J Med Entomol. 2009;46:723–36. https://doi.org/10.1603/033.046.0402 .
doi: 10.1603/033.046.0402
pubmed: 19645274
Piechocki R. Die Wildkatze Felis silvestris-Die Neue Brehm Bücherei A. 232; 1990.
Unterköfler MS, Harl J, Barogh BS, Spergser J, Hrazdilová K, Müller F, et al. Molecular analysis of blood-associated pathogens in European wildcats (Felis silvestris silvestris) from Germany. Int J Parasitol. 2022;19:128–37. https://doi.org/10.1016/j.ijppaw.2022.08.012 .
doi: 10.1016/j.ijppaw.2022.08.012
Obiegala A, Silaghi C. Candidatus Neoehrlichia Mikurensis—recent insights and future perspectives on clinical cases, vectors, and reservoirs in Europe. Curr Clin Micro Rpt. 2018;5:1–9. https://doi.org/10.1007/s40588-018-0085-y .
doi: 10.1007/s40588-018-0085-y
Stuen S, Granquist EG, Silaghi C. Anaplasma phagocytophilum–a widespread multi-host pathogen with highly adaptive strategies. Front Cell Infect Microbiol. 2013;3:31. https://doi.org/10.3389/fcimb.2013.00031 .
doi: 10.3389/fcimb.2013.00031
pubmed: 23885337
pmcid: 3717505
Schäfer I, Kohn B. Anaplasma phagocytophilum infection in cats: a literature review to raise clinical awareness. J Feline Med Surg. 2020;22:428–41. https://doi.org/10.1177/1098612X20917600 .
doi: 10.1177/1098612X20917600
pubmed: 32326861
pmcid: 7787687
Andréasson K, Jönsson G, Lindell P, Gülfe A, Ingvarsson R, Lindqvist E, et al. Recurrent fever caused by Candidatus Neoehrlichia mikurensis in a rheumatoid arthritis patient treated with rituximab. Rheumatology. 2015;54:369–71. https://doi.org/10.1093/rheumatology/keu441 .
doi: 10.1093/rheumatology/keu441
pubmed: 25416710
Shock BC, Murphy SM, Patton LL, Shock PM, Olfenbuttel C, Beringer J, et al. Distribution and prevalence of Cytauxzoon felis in bobcats (Lynx rufus), the natural reservoir, and other wild felids in thirteen states. Vet Parasitol. 2011;175:325–30. https://doi.org/10.1016/j.vetpar.2010.10.009 .
doi: 10.1016/j.vetpar.2010.10.009
pubmed: 21071149
Legroux J-P, Halos L, René-Martellet M, Servonnet M, Pingret J-L, Bourseau G, et al. First clinical case report of Cytauxzoon sp. infection in a domestic cat in France. BMC Vet Res. 2017;13:81. https://doi.org/10.1186/s12917-017-1009-4 .
doi: 10.1186/s12917-017-1009-4
pubmed: 28356105
pmcid: 5372320
Grillini M, Simonato G, Tessarin C, Dotto G, Traversa D, Cassini R, et al. Cytauxzoon sp. and Hepatozoon spp. in domestic cats: a preliminary study in North-Eastern Italy. Pathogens. 2021;10:1214. https://doi.org/10.3390/pathogens10091214 .
doi: 10.3390/pathogens10091214
pubmed: 34578245
pmcid: 8468074
Panait LC, Stock G, Globokar M, Balzer J, Groth B, Mihalca AD, et al. First report of Cytauxzoon sp. infection in Germany: organism description and molecular confirmation in a domestic cat. Parasitol Res. 2020;119:3005–11. https://doi.org/10.1007/s00436-020-06811-3 .
doi: 10.1007/s00436-020-06811-3
pubmed: 32677003
pmcid: 7366483
Willi B, Meli ML, Cafarelli C, Gilli UO, Kipar A, Hubbuch A, et al. Cytauxzoon europaeus infections in domestic cats in Switzerland and in European wildcats in France: a tale that started more than two decades ago. Parasites Vectors. 2022;15:19. https://doi.org/10.1186/s13071-021-05111-8 .
doi: 10.1186/s13071-021-05111-8
pubmed: 34998440
pmcid: 8742954
Díaz-Sánchez AA, Cabezas-Cruz A. Can domestic cats act as reservoirs of Cytauxzoon felis? Pathogens. 2023;12:266. https://doi.org/10.3390/pathogens12020266 .
doi: 10.3390/pathogens12020266
pubmed: 36839538
pmcid: 9967219
Bisterfeld K, Raulf M-K, Waindok P, Springer A, Lang J, Lierz M, et al. Cardio-pulmonary parasites of the European wildcat (Felis silvestris) in Germany. Parasites Vectors. 2022;15:452. https://doi.org/10.1186/s13071-022-05578-z .
doi: 10.1186/s13071-022-05578-z
pubmed: 36471378
pmcid: 9724372
Eskens U, Fischer M, Krüger M, Lang J, Müller F, Simon O, et al. Empfehlungen für die Aufarbeitung von Wildkatzen-Totfunden. Schriften des Arbeitskreises Wildbiologie an der Justus-Liebig-Universität Giessen e.V.Tagesband des Felis Symposium;. 2015:1–26.
Leonhardt I, Stockmann M, Bisterfeld K, Bächlein C, Cocchiararo B, Famira-Parcsetich EM, et al. Wildkatzen-Totfundmonitoring in Rheinland-Pfalz 2018–2020—Sachbericht des Projektes des BUND Rheinland-Pfalz gefördert durch das Ministerium für Umwelt, Energie, Ernährung und Forsten Rheinland-Pfalz (MUEEF) mit den Mitteln aus der AKTION GRÜN. 2021.
Famira-Parcsetich E, Westhoff K, Schanzer S, Nemitz S, Müller C, Schenke D, et al., Editors. Die Toten lügen nicht – Totfundanalysen als Beitrag zum Wildtiermonitoring am Beispiel der Europäischen Wildkatze und des Gartenschläfers. In: Wildbiologische Forschungsberichte 2022.: Kessel Verlag; 2022.
Courtney JW, Kostelnik LM, Zeidner NS, Massung RF. Multiplex real-time PCR for detection of Anaplasma phagocytophilum and Borrelia burgdorferi. J Clin Microbiol. 2004;42:3164–8. https://doi.org/10.1128/jcm.42.7.3164-3168.2004 .
doi: 10.1128/jcm.42.7.3164-3168.2004
pubmed: 15243077
pmcid: 446246
Jahfari S, Fonville M, Hengeveld P, Reusken C, Scholte E-J, Takken W, et al. Prevalence of Neoehrlichia mikurensis in ticks and rodents from North-west Europe. Parasites Vectors. 2012;5:74. https://doi.org/10.1186/1756-3305-5-74 .
doi: 10.1186/1756-3305-5-74
pubmed: 22515314
pmcid: 3395572
Wölfel R, Essbauer S, Dobler G. Diagnostics of tick-borne rickettsioses in Germany: a modern concept for a neglected disease. Int J Med Microbiol. 2008;298:368–74. https://doi.org/10.1016/j.ijmm.2007.11.009 .
doi: 10.1016/j.ijmm.2007.11.009
Roux V, Raoult D. Phylogenetic analysis of members of the genus Rickettsia using the gene encoding the outer-membrane protein rOmpB (ompB). Int J Syst Evol Microbiol. 2000;50:1449–55. https://doi.org/10.1099/00207713-50-4-1449 .
doi: 10.1099/00207713-50-4-1449
pubmed: 10939649
Kosoy MY, Regnery RL, Tzianabos T, Marston EL, Jones DC, Green D, et al. Distribution, diversity, and host specificity of Bartonella in rodents from the Southeastern United States. Am J Trop Med Hyg. 1997;57:578–88. https://doi.org/10.4269/ajtmh.1997.57.578 .
doi: 10.4269/ajtmh.1997.57.578
pubmed: 9392599
Maggi RG, Chomel B, Hegarty BC, Henn J, Breitschwerdt EB. A Bartonella vinsonii berkhoffii typing scheme based upon 16S–23S ITS and Pap31 sequences from dog, coyote, gray fox, and human isolates. Mol Cell Probes. 2006;20:128–34. https://doi.org/10.1016/j.mcp.2005.11.002 .
doi: 10.1016/j.mcp.2005.11.002
pubmed: 16460911
Norman AF, Regnery R, Jameson P, Greene C, Krause DC. Differentiation of Bartonella-like isolates at the species level by PCR-restriction fragment length polymorphism in the citrate synthase gene. J Clin Microbiol. 1995;33:1797–803. https://doi.org/10.1128/jcm.33.7.1797-1803.1995 .
doi: 10.1128/jcm.33.7.1797-1803.1995
pubmed: 7545181
pmcid: 228273
Colborn JM, Kosoy MY, Motin VL, Telepnev MV, Valbuena G, Myint KS, et al. Improved detection of Bartonella DNA in mammalian hosts and arthropod vectors by real-time PCR using the NADH dehydrogenase gamma subunit (nuoG). J Clin Microbiol. 2010;48:4630–3. https://doi.org/10.1128/JCM.00470-10 .
doi: 10.1128/JCM.00470-10
pubmed: 20926707
pmcid: 3008469
Böge I, Pfeffer M, Htwe NM, Maw PP, Sarathchandra SR, Sluydts V, et al. First detection of Bartonella spp. in small mammals from rice storage and processing facilities in Myanmar and Sri Lanka. Microorganisms. 2021;9:658. https://doi.org/10.3390/microorganisms9030658 .
doi: 10.3390/microorganisms9030658
pubmed: 33810195
pmcid: 8004705
Casati S, Sager H, Gern L, Piffaretti JC. Presence of potentially pathogenic Babesia sp. for human in Ixodes ricinus in Switzerland. Ann Agric Environ Med. 2006;13:65.
pubmed: 16841874
Schorn S, Pfister K, Reulen H, Mahling M, Silaghi C. Occurrence of Babesia spp., Rickettsia spp. and Bartonella spp. in Ixodes ricinus in Bavarian public parks, Germany. Parasites Vectors. 2011;4:135. https://doi.org/10.1186/1756-3305-4-135 .
doi: 10.1186/1756-3305-4-135
pubmed: 21762494
pmcid: 3154157
Millán J, Naranjo V, Rodríguez A, La Lastra JP de, Mangold AJ, La Fuente J de. Prevalence of infection and 18S rRNA gene sequences of Cytauxzoon species in Iberian lynx (Lynx pardinus) in Spain. Parasitology. 2007;134: 995
Gallusová M, Jirsová D, Mihalca AD, Gherman CM, D’Amico G, Qablan MA, et al. Cytauxzoon infections in wild felids from Carpathian-Danubian-Pontic space: further evidence for a different Cytauxzoon species in European felids. J Parasitol. 2016;102:377–80. https://doi.org/10.1645/15-881 .
doi: 10.1645/15-881
pubmed: 26741977
Panait LC, Mihalca AD, Modrý D, Juránková J, Ionică AM, Deak G, et al. Three new species of Cytauxzoon in European wild felids. Vet Parasitol. 2021;290:109344. https://doi.org/10.1016/j.vetpar.2021.109344 .
doi: 10.1016/j.vetpar.2021.109344
pubmed: 33465567
Reichard MV, Meinkoth JH, Edwards AC, Snider TA, Kocan KM, Blouin EF, et al. Transmission of Cytauxzoon felis to a domestic cat by Amblyomma americanum. Vet Parasitol. 2009;161:110–5. https://doi.org/10.1016/j.vetpar.2008.12.016 .
doi: 10.1016/j.vetpar.2008.12.016
pubmed: 19168288
Blouin EF, Kocan AA, Glenn BL, Kocan KM, Hair JA. Transmission of Cytauxzoon felis Kier, 1979 from bobcats, Felis rufus (Schreber), to domestic cats by Dermacentor variabilis (Say). J Wildl Dis. 1984;20:241–2. https://doi.org/10.7589/0090-3558-20.3.241 .
doi: 10.7589/0090-3558-20.3.241
pubmed: 6492329
Deplazes P, van Knapen F, Schweiger A, Overgaauw PA. Role of pet dogs and cats in the transmission of helminthic zoonoses in Europe, with a focus on echinococcosis and toxocarosis. Vet Parasitol. 2011;182:41–53. https://doi.org/10.1016/j.vetpar.2011.07.014 .
doi: 10.1016/j.vetpar.2011.07.014
pubmed: 21813243
Wang J-L, Li T-T, Liu G-H, Zhu X-Q, Yao C. Two tales of Cytauxzoon felis infections in domestic cats. Clin Microbiol Rev. 2017;30:861–85. https://doi.org/10.1128/CMR.00010-17 .
doi: 10.1128/CMR.00010-17
pubmed: 28637681
pmcid: 5608878
Veronesi F, Ravagnan S, Cerquetella M, Carli E, Olivieri E, Santoro A, et al. First detection of Cytauxzoon spp infection in European wildcats (Felis silvestris silvestris) of Italy. Ticks Tick-borne Dis. 2016;7:853–8. https://doi.org/10.1016/j.ttbdis.2016.04.003 .
doi: 10.1016/j.ttbdis.2016.04.003
pubmed: 27150590
Grillini M, Beraldo P, Di Frangipane RA, Dotto G, Tessarin C, Franzo G, et al. Molecular survey of Cytauxzoon spp. and Hepatozoon spp. in felids using a novel real-time PCR approach. Front Vet Sci. 2023;10:1113681. https://doi.org/10.3389/fvets.2023.1113681 .
doi: 10.3389/fvets.2023.1113681
pubmed: 37377952
pmcid: 10291185
Nentwig A, Meli ML, Schrack J, Reichler IM, Riond B, Gloor C, et al. First report of Cytauxzoon sp. infection in domestic cats in Switzerland: natural and transfusion-transmitted infections. Parasites Vectors. 2018;11:292. https://doi.org/10.1186/s13071-018-2728-5 .
doi: 10.1186/s13071-018-2728-5
pubmed: 29747680
pmcid: 5944068
Carli E, Solano-Gallego L, de Arcangeli S, Ventura L, Ligorio E, Furlanello T. Clinicopathological findings and risk factors associated with Cytauxzoon spp. infection in cats: a case-control study (2008–2021). Front Vet Sci. 2022;9:976173. https://doi.org/10.3389/fvets.2022.976173 .
doi: 10.3389/fvets.2022.976173
pubmed: 36439359
pmcid: 9685617
Santos-Silva MM, Melo P, Santos N, Antunes S, Duarte LR, Ferrolho J, et al. PCR screening of tick-borne agents in sensitive conservation areas, Southeast Portugal. Mol Cell Probes. 2017;31:42–5. https://doi.org/10.1016/j.mcp.2016.11.005 .
doi: 10.1016/j.mcp.2016.11.005
pubmed: 27894847
Arz C, Król N, Imholt C, Jeske K, Rentería-Solís Z, Ulrich RG, et al. Spotted fever group rickettsiae in ticks and small mammals from grassland and forest habitats in Central Germany. Pathogens. 2023;12:933. https://doi.org/10.3390/pathogens12070933 .
doi: 10.3390/pathogens12070933
pubmed: 37513780
pmcid: 10386184
Beck R, Čurik V, Ivana R, Nikica Š, Anja V. Identification of ‘Candidatus Neoehrlichia mikurensis’ and Anaplasma species in wildlife from Croatia. Parasites Vectors. 2014;7:O28. https://doi.org/10.1186/1756-3305-7-S1-O28 .
doi: 10.1186/1756-3305-7-S1-O28
pmcid: 4094298
Wennerås C. Infections with the tick-borne bacterium Candidatus Neoehrlichia mikurensis. Clin Microbiol Infect. 2015;21:621–30. https://doi.org/10.1016/j.cmi.2015.02.030 .
doi: 10.1016/j.cmi.2015.02.030
pubmed: 25770773
Márquez FJ, Millán J. Rickettsiae in ticks from wild and domestic carnivores of Doñana National Park (Spain) and surrounding area. Clin Microbiol Infect. 2009;15:224–6. https://doi.org/10.1111/j.1469-0691.2008.02147.x .
doi: 10.1111/j.1469-0691.2008.02147.x
pubmed: 19456821
Grassi L, Menandro ML, Cassini R, Mondin A, Pasotto D, Grillini M, et al. High prevalence of tick-borne zoonotic Rickettsia slovaca in ticks from wild boars, Northeastern Italy. Animals. 2022;12:967. https://doi.org/10.3390/ani12080967 .
doi: 10.3390/ani12080967
pubmed: 35454214
pmcid: 9025954
Stefanidesova K, Kocianova E, Boldis V, Kostanova Z, Kanka P, Nemethova D, et al. Evidence of Anaplasma phagocytophilum and Rickettsia helvetica infection in free-ranging ungulates in central Slovakia. Eur J Wildl Res. 2008;54:519–24. https://doi.org/10.1007/s10344-007-0161-8 .
doi: 10.1007/s10344-007-0161-8
Obiegala A, Oltersdorf C, Silaghi C, Kiefer D, Kiefer M, Woll D, et al. Rickettsia spp. in small mammals and their parasitizing ectoparasites from Saxony, Germany. Vet Parasitol. 2016;5:19–24. https://doi.org/10.1016/j.vprsr.2016.08.008 .
doi: 10.1016/j.vprsr.2016.08.008
Krügel M, Król N, Kempf VAJ, Pfeffer M, Obiegala A. Emerging rodent-associated Bartonella: a threat for human health? Parasites Vectors. 2022;15:113. https://doi.org/10.1186/s13071-022-05162-5 .
doi: 10.1186/s13071-022-05162-5
pubmed: 35361285
pmcid: 8969336
Holmberg M, Mills JN, McGill S, Benjamin G, Ellis BA. Bartonella infection in sylvatic small mammals of central Sweden. Epidemiol Infect. 2003;130:149–57. https://doi.org/10.1017/s0950268802008075 .
doi: 10.1017/s0950268802008075
pubmed: 12613756
pmcid: 2869949
Obiegala A, Jeske K, Augustin M, Król N, Fischer S, Mertens-Scholz K, et al. Highly prevalent bartonellae and other vector-borne pathogens in small mammal species from the Czech Republic and Germany. Parasites Vectors. 2019;12:332. https://doi.org/10.1186/s13071-019-3576-7 .
doi: 10.1186/s13071-019-3576-7
pubmed: 31269975
pmcid: 6610854
Bown KJ, Bennet M, Begon M. Flea-borne Bartonella grahamii and Bartonella taylorii in bank voles. Emerg Infect Dis. 2004;10:684–7. https://doi.org/10.3201/eid1004.030455 .
doi: 10.3201/eid1004.030455
pubmed: 15200860
pmcid: 3323072
Lang J, editor. Die Katze lässt das Mausen nicht− Aktuelle Ergebnisse einer Nahrungsanalyse an Europäischen Wildkatzen aus dem Zentrum ihrer Verbreitung; 2016.
Jahfari S, Coipan EC, Fonville M, van Leeuwen AD, Hengeveld P, Heylen D, et al. Circulation of four Anaplasma phagocytophilum ecotypes in Europe. Parasites Vectors. 2014;7:365. https://doi.org/10.1186/1756-3305-7-365 .
doi: 10.1186/1756-3305-7-365
pubmed: 25127547
pmcid: 4153903
Hornok S, Boldogh SA, Takács N, Sándor AD, Tuska-Szalay B. Zoonotic ecotype-I of Anaplasma phagocytophilum in sympatric wildcat, pine marten and red squirrel—short communication. Acta Vet Hung. 2022;70:215–9. https://doi.org/10.1556/004.2022.00021 .
doi: 10.1556/004.2022.00021
Matei IA, Ivan T, Ionică AM, D’Amico G, Deak G, Nadas GC, et al. Anaplasma phagocytophilum in multiple tissue samples of wild carnivores in Romania. J Wildl Dis. 2021;57:949–53. https://doi.org/10.7589/JWD-D-20-00158 .
doi: 10.7589/JWD-D-20-00158
pubmed: 34427664