Selagibenzophenone B and Its Derivatives:


Journal

ACS bio & med chem Au
ISSN: 2694-2437
Titre abrégé: ACS Bio Med Chem Au
Pays: United States
ID NLM: 9918232604406676

Informations de publication

Date de publication:
21 Aug 2024
Historique:
received: 24 04 2024
revised: 26 06 2024
accepted: 27 06 2024
medline: 26 8 2024
pubmed: 26 8 2024
entrez: 26 8 2024
Statut: epublish

Résumé

The development of multitargeted drugs represents an innovative approach to cancer treatment, aiming to enhance drug effectiveness while minimizing side effects. Herein, we sought to elucidate the inhibitory effect of selagibenzophenone B derivatives on the survival of cancer cells and dual topoisomerase I/II enzyme activity. Results demonstrated that among the compounds,

Identifiants

pubmed: 39184056
doi: 10.1021/acsbiomedchemau.4c00027
pmc: PMC11342340
doi:

Types de publication

Journal Article

Langues

eng

Pagination

178-189

Informations de copyright

© 2024 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

Auteurs

Serhat Dönmez (S)

Graduate Program of Molecular Biology and Genetics, School of Graduate Studies, Canakkale Onsekiz Mart University, Canakkale 17020, Turkey.

Ringaile Lapinskaite (R)

Department of Organic Chemistry, Center for Physical Sciences and Technology (FTMC), Akademijos g. 7, Vilnius LT-08412, Lithuania.
Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 43 Praha 2, Czechia.

Hazal Nazlican Atalay (HN)

Graduate Program of Molecular Biology and Genetics, School of Graduate Studies, Canakkale Onsekiz Mart University, Canakkale 17020, Turkey.

Esra Tokay (E)

Department of Molecular Biology and Genetics, Faculty of Sciences and Arts, Balikesir University, Balikesir 10145, Turkey.

Feray Kockar (F)

Department of Molecular Biology and Genetics, Faculty of Sciences and Arts, Balikesir University, Balikesir 10145, Turkey.

Lukas Rycek (L)

Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 43 Praha 2, Czechia.

Mehmet Özbil (M)

Institute of Biotechnology, Gebze Technical University, Kocaeli 41400, Turkey.

Tugba Boyunegmez Tumer (TB)

Department of Molecular Biology and Genetics, Faculty of Science, Canakkale Onsekiz Mart University, Canakkale 17020, Turkey.

Classifications MeSH