A rare presentation of rhino-orbital-cutaneous mucormycosis in an immunocompetent patient: a case report.
Humans
Mucormycosis
/ diagnosis
Antifungal Agents
/ administration & dosage
Amphotericin B
/ administration & dosage
Male
Debridement
/ methods
Dermatomycoses
/ diagnosis
Immunocompetence
Orbital Cellulitis
/ diagnosis
Orbital Diseases
/ diagnosis
Mucorales
/ isolation & purification
Middle Aged
Headache
/ etiology
Mucormycosis
antifungal
case report
communicable
fungal infection
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2024
2024
Historique:
received:
30
03
2024
accepted:
03
05
2024
medline:
26
8
2024
pubmed:
26
8
2024
entrez:
26
8
2024
Statut:
epublish
Résumé
Mucormycosis is a rare opportunistic infection caused by Mucorales fungi. Cutaneous mucormycosis typically present as chronic indolent infection, whereas rhino-orbital mucormycosis is rapidly progressive disease often invade the adjacent cerebral tissue associated with high mortality. This case represents the atypical clinical history of rhino-orbital-cutaneous mucormycosis. The patient was presented with a right orbital cellulitis associated with an extensive multiple suppurative deep cutaneous infection and worsening headache. The skin lesion was initiated from a localized abscess at the right periorbital area nine months before admission. Suspicion of fungal infection was raised after weeks of non-responsive antibiotics treatment. Aggressive treatment with exoneration of the right eye and surgical debridement was undertaken. Periodic acid Schiff staining from healthy periorbital tissue revealed ribbon-like hyphae with pauciseptate and 90° branching identified as Mucoraceaefamily. The resolution was seen after four weeks of antifungal treatment with Amphotericin B.
Identifiants
pubmed: 39184848
doi: 10.11604/pamj.2024.48.13.43454
pii: PAMJ-48-13
pmc: PMC11343495
doi:
Substances chimiques
Antifungal Agents
0
Amphotericin B
7XU7A7DROE
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
13Informations de copyright
Copyright: Ni Putu Ayu Reza Dhiyantari et al.
Déclaration de conflit d'intérêts
The authors declare no competing interest.