A rare presentation of rhino-orbital-cutaneous mucormycosis in an immunocompetent patient: a case report.


Journal

The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926

Informations de publication

Date de publication:
2024
Historique:
received: 30 03 2024
accepted: 03 05 2024
medline: 26 8 2024
pubmed: 26 8 2024
entrez: 26 8 2024
Statut: epublish

Résumé

Mucormycosis is a rare opportunistic infection caused by Mucorales fungi. Cutaneous mucormycosis typically present as chronic indolent infection, whereas rhino-orbital mucormycosis is rapidly progressive disease often invade the adjacent cerebral tissue associated with high mortality. This case represents the atypical clinical history of rhino-orbital-cutaneous mucormycosis. The patient was presented with a right orbital cellulitis associated with an extensive multiple suppurative deep cutaneous infection and worsening headache. The skin lesion was initiated from a localized abscess at the right periorbital area nine months before admission. Suspicion of fungal infection was raised after weeks of non-responsive antibiotics treatment. Aggressive treatment with exoneration of the right eye and surgical debridement was undertaken. Periodic acid Schiff staining from healthy periorbital tissue revealed ribbon-like hyphae with pauciseptate and 90° branching identified as Mucoraceaefamily. The resolution was seen after four weeks of antifungal treatment with Amphotericin B.

Identifiants

pubmed: 39184848
doi: 10.11604/pamj.2024.48.13.43454
pii: PAMJ-48-13
pmc: PMC11343495
doi:

Substances chimiques

Antifungal Agents 0
Amphotericin B 7XU7A7DROE

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

13

Informations de copyright

Copyright: Ni Putu Ayu Reza Dhiyantari et al.

Déclaration de conflit d'intérêts

The authors declare no competing interest.

Auteurs

Ni Putu Ayu Reza Dhiyantari (NPAR)

Department of Ophthalmology, Faculty of Medicine Airlangga University, Dr Soetomo Hospital Surabaya, Surabaya, Indonesia.

Delfitri Lutfi (D)

Department of Ophthalmology, Faculty of Medicine Airlangga University, Dr Soetomo Hospital Surabaya, Surabaya, Indonesia.

Dwi Hari Susilo (DH)

Department of Head and Neck Surgery, Faculty of Medicine Airlangga University, Dr Soetomo Hospital Surabaya, Surabaya, Indonesia.

Irwan Kristyono (I)

Department of Ear, Nose and Throat (ENT), Faculty of Medicine Airlangga University, Dr Soetomo Hospital Surabaya, Surabaya, Indonesia.

Alicia Widya (A)

Department of Microbiology, Faculty of Medicine Airlangga University, Dr Soetomo Hospital Surabaya, Surabaya, Indonesia.

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Classifications MeSH