Assessing the impact of different Urushiol primer solvents on dentin remineralization and bond strength.
Humans
Microscopy, Electron, Scanning
Spectroscopy, Fourier Transform Infrared
Dentin
/ drug effects
Tensile Strength
Tooth Remineralization
/ methods
Materials Testing
Solvents
/ chemistry
X-Ray Diffraction
Dentin-Bonding Agents
/ chemistry
Spectrum Analysis, Raman
Surface Properties
Dental Bonding
/ methods
Microscopy, Atomic Force
In Vitro Techniques
Acid Etching, Dental
Spectrometry, X-Ray Emission
Molar
Cross-Linking Reagents
/ chemistry
Hardness
Bonding durability
Collagen cross-linking
Hydroxyapatite
Remineralization
Urushiol
Journal
Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115
Informations de publication
Date de publication:
26 Aug 2024
26 Aug 2024
Historique:
received:
11
06
2024
accepted:
17
08
2024
medline:
26
8
2024
pubmed:
26
8
2024
entrez:
26
8
2024
Statut:
epublish
Résumé
To investigate urushiol's potential as a dentin cross-linking agent, promoting remineralization of etched dentin and preventing activation of endogenous proteases causing collagen degradation within the hybrid layer. The goal is to improve bond strength and durability at the resin-dentin interface. Urushiol primers with varying concentrations were prepared using ethanol and dimethyl sulfoxide (DMSO) as solvents. Dentin from healthy molars underwent grinding and acid etching for 15 s, followed by a 1min application of urushiol primer. After 14 and 28 days of remineralization incubation and remineralization were used to assess by Attenuated Total Reflection Fourier Transform Infrared spectroscopy (ATR-FTIR), Micro-Raman spectroscopy, X-ray Diffraction (XRD), Atomic Force Microscopy (AFM), Vickers Hardness, Scanning Electron Microscopy (SEM), and Energy X-ray dispersive spectroscopy (EDS). The overall performance of urushiol primers as dentin adhesives was observed by microtensile bond strength (μTBS) testing and nanoleakage assessment. Investigated the inhibitory properties of the urushiol primers on endogenous metalloproteinases (MMPs) utilizing in situ zymography, and the cytotoxicity of the primers was tested. Based on ATR-FTIR, Raman, XRD, EM-EDS and Vickers hardness analyses, the 0.7%-Ethanol group significantly enhanced dentin mineral content and improved mechanical properties the most. Pretreatment notably increased the μTBS of restorations, promoted the stability of the mixed layer, and reduced nanoleakage and MMPs activity after 28 days. The urushiol primer facilitates remineralization in demineralized dentin, enhancing remineralization in etched dentin, effectively improving the bonding interface stability, with optimal performance observed at a 0.7 wt% concentration of the urushiol primer.
Identifiants
pubmed: 39186077
doi: 10.1007/s00784-024-05892-z
pii: 10.1007/s00784-024-05892-z
doi:
Substances chimiques
Solvents
0
Dentin-Bonding Agents
0
Cross-Linking Reagents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
500Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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