The association between patella alignment and morphology and knee osteoarthritis.
Alignment
Kinematics
Kinetics
Knee
Morphology
Patella
Journal
Journal of orthopaedic surgery and research
ISSN: 1749-799X
Titre abrégé: J Orthop Surg Res
Pays: England
ID NLM: 101265112
Informations de publication
Date de publication:
27 Aug 2024
27 Aug 2024
Historique:
received:
26
03
2024
accepted:
16
08
2024
medline:
28
8
2024
pubmed:
28
8
2024
entrez:
27
8
2024
Statut:
epublish
Résumé
This study aims to quantitatively assess the relationship between the patella alignment and morphology and knee osteoarthritis (KOA), as well as the kinematics and kinetics of the knee, using gait analysis. Eighty age-matched patients with KOA and control subjects were evaluated. Incident radiographic osteoarthritis (iROA) was identified using a Kellgren-Lawrence (KL) grade of ≥ 2. The modified Insall-Salvati ratio (Mod-ISR), patellar tilt angle (PTA), and patella index (PI) were utilized to evaluate the sagittal and transverse alignment of the patella and its morphology, respectively. Regression analyses were conducted to explore associations between patellar measurements and KOA, iROA, kinematics, and kinetics. Significant differences were observed between the control and KOA groups in terms of KL grade, patella alta, abduction angle, and reaction force to the ground (P < 0.05, respectively). Following adjustment for covariates, a significant positive association was found between patella alta and KOA (OR = 0.307, 95%CI: 0.103 to 0.918, P = 0.035). Additionally, a significant negative association was observed between PTA and abduction angle (B = -0.376, 95%CI: -0.751 to -0.002; P = 0.049). The PI exhibited a statistically significant association with log-transformed vertical ground reaction force (B = 0.002, 95%CI: 0.001 to 0.003, P = 0.002). Furthermore, adjustment for covariates did not reveal any significant correlations with other indicators (P > 0.05, respectively). This study provides further evidence that proper alignment and morphology of the patella might be associated with maintaining normal biomechanical function. In addition, intervention measures targeting relevant patellar parameters, such as Mod-ISR, PTA, and PI, may positively impact KOA treatment outcomes.
Identifiants
pubmed: 39192379
doi: 10.1186/s13018-024-05001-6
pii: 10.1186/s13018-024-05001-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
509Subventions
Organisme : Shanghai Municipal Health Commission
ID : 20MC1920600
Organisme : National Natural Science Foundation of China
ID : 82074466
Organisme : National Science Foundation
ID : 82374481
Informations de copyright
© 2024. The Author(s).
Références
Leyland KM, Gates LS, Sanchez-Santos MT, Nevitt MC, Felson D, Jones G, Jordan JM, Judge A, Prieto-Alhambra D, Yoshimura N, et al. Knee osteoarthritis and time-to all-cause mortality in six community-based cohorts: an international meta-analysis of individual participant-level data. Aging Clin Exp Res. 2021;33(3):529–45.
pubmed: 33590469
pmcid: 7943431
doi: 10.1007/s40520-020-01762-2
Yahaya I, Wright T, Babatunde OO, Corp N, Helliwell T, Dikomitis L, Mallen CD. Prevalence of osteoarthritis in lower middle- and low-income countries: a systematic review and meta-analysis. Rheumatol Int. 2021;41(7):1221–31.
pubmed: 33907879
pmcid: 8164595
doi: 10.1007/s00296-021-04838-y
Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the global burden of Disease Study 2010. Lancet. 2012;380(9859):2163–96.
pubmed: 23245607
pmcid: 6350784
doi: 10.1016/S0140-6736(12)61729-2
Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine 2020, 29–30:100587.
Freijo V, Navarro C, Molina B, Villalba J. Low correlation between Gait and Quality of Life in Advanced knee osteoarthritis. J Funct Morphol Kinesiol 2023, 8(2).
Yan M, Liang T, Zhao H, Bi Y, Wang T, Yu T, Zhang Y. Model properties and clinical application in the Finite element analysis of knee Joint: a review. Orthop Surg. 2024;16(2):289–302.
pubmed: 38174410
pmcid: 10834231
doi: 10.1111/os.13980
Logerstedt DS, Ebert JR, MacLeod TD, Heiderscheit BC, Gabbett TJ, Eckenrode BJ. Effects of and response to mechanical loading on the knee. Sports Med. 2022;52(2):201–35.
pubmed: 34669175
doi: 10.1007/s40279-021-01579-7
Vina ER, Kwoh CK. Epidemiology of osteoarthritis: literature update. Curr Opin Rheumatol. 2018;30(2):160–7.
pubmed: 29227353
pmcid: 5832048
doi: 10.1097/BOR.0000000000000479
van Tunen JA, Dell’Isola A, Juhl C, Dekker J, Steultjens M, Lund H. Biomechanical factors associated with the development of tibiofemoral knee osteoarthritis: protocol for a systematic review and meta-analysis. BMJ Open. 2016;6(6):e011066.
pubmed: 27311908
pmcid: 4916579
doi: 10.1136/bmjopen-2016-011066
Georgiev T, Angelov AK. Modifiable risk factors in knee osteoarthritis: treatment implications. Rheumatol Int. 2019;39(7):1145–57.
pubmed: 30911813
doi: 10.1007/s00296-019-04290-z
Sit RWS, Chan KKW, Zou D, Chan DCC, Yip BHK, Zhang DD, Chan YH, Chung VCH, Reeves KD, Wong SYS. Clinic-based patellar mobilization therapy for knee osteoarthritis: a Randomized Clinical Trial. Ann Fam Med. 2018;16(6):521–9.
pubmed: 30420367
pmcid: 6231921
doi: 10.1370/afm.2320
Connolly KD, Ronsky JL, Westover LM, Küpper JC, Frayne R. Differences in patellofemoral contact mechanics associated with patellofemoral pain syndrome. J Biomech. 2009;42(16):2802–7.
pubmed: 19889417
doi: 10.1016/j.jbiomech.2009.07.028
Ward SR, Terk MR, Powers CM. Patella alta: association with patellofemoral alignment and changes in contact area during weight-bearing. J Bone Joint Surg Am. 2007;89(8):1749–55.
pubmed: 17671014
White DK, Master H. Patient-reported measures of physical function in knee osteoarthritis. Rheum Dis Clin North Am. 2016;42(2):239–52.
pubmed: 27133487
pmcid: 4853650
doi: 10.1016/j.rdc.2016.01.005
Tanpure S, Phadnis A, Nagda T, Rathod C, Kothurkar R, Chavan A. Gait variability and biomechanical distinctions in knee osteoarthritis: insights from a 3D analysis in an adult elderly cohort. J Orthop. 2024;49:172–9.
pubmed: 38234966
doi: 10.1016/j.jor.2023.12.011
Zhang W, Doherty M, Peat G, Bierma-Zeinstra MA, Arden NK, Bresnihan B, Herrero-Beaumont G, Kirschner S, Leeb BF, Lohmander LS, et al. EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis. Ann Rheum Dis. 2010;69(3):483–9.
pubmed: 19762361
doi: 10.1136/ard.2009.113100
Grelsamer RP. S Meadows 1992 The modified Insall-Salvati ratio for assessment of patellar height. Clin Orthop Relat Res 282 170–6.
Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957;16(4):494–502.
pubmed: 13498604
pmcid: 1006995
doi: 10.1136/ard.16.4.494
Kohn MD, Sassoon AA, Fernando ND. Classifications in brief: Kellgren-Lawrence classification of Osteoarthritis. Clin Orthop Relat Res. 2016;474(8):1886–93.
pubmed: 26872913
pmcid: 4925407
doi: 10.1007/s11999-016-4732-4
Sasaki T, Yagi T. Subluxation of the patella: investigation by computerized tomography. Int Orthop. 1986;10(2):115–20.
pubmed: 27743060
doi: 10.1007/BF00267752
Cross MJ, Waldrop J. The patella index as a guide to the understanding and diagnosis of patellofemoral instability. Clin Orthop Relat Res 1975(110):174–6.
Zhang M, Pang J, Lu J, Kang M, Chen B, Jones RK, Zhan H, Liu A. The Immediate Effect of Backward Walking on External Knee Adduction Moment in Healthy Individuals. J Healthc Eng 2022, 2022:4232990.
Jones RK, Zhang M, Laxton P, Findlow AH, Liu A. The biomechanical effects of a new design of lateral wedge insole on the knee and ankle during walking. Hum Mov Sci. 2013;32(4):596–604.
pubmed: 24054897
doi: 10.1016/j.humov.2012.12.012
Riazati S, McGuirk TE, Perry ES, Sihanath WB, Patten C. Absolute reliability of Gait parameters Acquired with Markerless Motion capture in living domains. Front Hum Neurosci. 2022;16:867474.
pubmed: 35782037
pmcid: 9245068
doi: 10.3389/fnhum.2022.867474
Büttner C, Lisee C, Buck A, Bjornsen E, Thoma L, Spang J, Blackburn T, Pietrosimone B. Early Gait Biomechanics Linked to Daily steps following anterior Cruciate Ligament Reconstruction. J Athl Train 2024.
Zikria B, Rinaldi J, Guermazi A, Haj-Mirzaian A, Pishgar F, Roemer FW, Hakky M, Sereni C, Demehri S. Lateral patellar tilt and its longitudinal association with patellofemoral osteoarthritis-related structural damage: analysis of the osteoarthritis initiative data. Knee. 2020;27(6):1971–9.
pubmed: 33248351
doi: 10.1016/j.knee.2020.11.002
Roemer FW, Jarraya M, Hayashi D, Crema MD, Haugen IK, Hunter DJ, Guermazi A. A perspective on the evolution of semi-quantitative MRI assessment of osteoarthritis: past, present and future. Osteoarthritis Cartilage 2024.
Stefanik JJ, Guermazi A, Zhu Y, Zumwalt AC, Gross KD, Clancy M, Lynch JA, Segal NA, Lewis CE, Roemer FW, et al. Quadriceps weakness, patella alta, and structural features of patellofemoral osteoarthritis. Arthritis Care Res (Hoboken). 2011;63(10):1391–7.
pubmed: 21702087
doi: 10.1002/acr.20528
Insall J, Salvati E. Patella position in the normal knee joint. Radiology. 1971;101(1):101–4.
pubmed: 5111961
doi: 10.1148/101.1.101
Biedert RM, Tscholl PM. Patella Alta: a Comprehensive Review of current knowledge. Am J Orthop (Belle Mead NJ). 2017;46(6):290–300.
pubmed: 29309446
Pfitzner T, Perka C, Matziolis G. [Patella height after total knee replacement: influence of the radiological setting]. Orthopade. 2009;38(7):616–21.
pubmed: 19513692
doi: 10.1007/s00132-009-1437-3
Jibri Z, Jamieson P, Rakhra KS, Sampaio ML, Dervin G. Patellar maltracking: an update on the diagnosis and treatment strategies. Insights Imaging. 2019;10(1):65.
pubmed: 31201575
pmcid: 6570735
doi: 10.1186/s13244-019-0755-1
Kalichman L, Zhang Y, Niu J, Goggins J, Gale D, Felson DT, Hunter D. The association between patellar alignment and patellofemoral joint osteoarthritis features–an MRI study. Rheumatology (Oxford). 2007;46(8):1303–8.
pubmed: 17525117
doi: 10.1093/rheumatology/kem095
Ward SR, Powers CM. The influence of patella alta on patellofemoral joint stress during normal and fast walking. Clin Biomech (Bristol Avon). 2004;19(10):1040–7.
pubmed: 15531054
doi: 10.1016/j.clinbiomech.2004.07.009
Widjajahakim R, Roux M, Jarraya M, Roemer FW, Neogi T, Lynch JA, Lewis CE, Torner JC, Felson DT, Guermazi A, et al. Relationship of Trochlear morphology and Patellofemoral Joint Alignment to Superolateral Hoffa Fat Pad Edema on MR images in individuals with or at risk for Osteoarthritis of the knee: the MOST study. Radiology. 2017;284(3):806–14.
pubmed: 28418810
doi: 10.1148/radiol.2017162342
Stefanik JJ, Zhu Y, Zumwalt AC, Gross KD, Clancy M, Lynch JA, Frey Law LA, Lewis CE, Roemer FW, Powers CM, et al. Association between patella alta and the prevalence and worsening of structural features of patellofemoral joint osteoarthritis: the multicenter osteoarthritis study. Arthritis Care Res (Hoboken). 2010;62(9):1258–65.
pubmed: 20506169
doi: 10.1002/acr.20214
Haj-Mirzaian A, Guermazi A, Pishgar F, Pourvaziri A, Roemer FW, Sereni C, Hakky M, Zikria B, Stefanik JJ, Demehri S. Association of patella alta with worsening of patellofemoral osteoarthritis-related structural damage: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2019;27(2):278–85.
pubmed: 30445221
doi: 10.1016/j.joca.2018.10.013
Macri EM, Felson DT, Zhang Y, Guermazi A, Roemer FW, Crossley KM, Khan KM, Stefanik JJ. Patellofemoral morphology and alignment: reference values and dose-response patterns for the relation to MRI features of patellofemoral osteoarthritis. Osteoarthritis Cartilage. 2017;25(10):1690–7.
pubmed: 28648740
pmcid: 5605424
doi: 10.1016/j.joca.2017.06.005
van Middelkoop M, Macri EM, Eijkenboom JF, van der Heijden RA, Crossley KM, Bierma-Zeinstra SMA, de Kanter JL, Oei EH, Collins NJ. Are Patellofemoral Joint alignment and shape Associated with Structural magnetic resonance imaging abnormalities and symptoms among people with Patellofemoral Pain? Am J Sports Med. 2018;46(13):3217–26.
pubmed: 30321064
pmcid: 6236631
doi: 10.1177/0363546518801314
Stephen JM, Kader D, Lumpaopong P, Deehan DJ, Amis AA. Sectioning the medial patellofemoral ligament alters patellofemoral joint kinematics and contact mechanics. J Orthop Res. 2013;31(9):1423–9.
pubmed: 23629829
doi: 10.1002/jor.22371
Lankhorst NE, Bierma-Zeinstra SM, van Middelkoop M. Factors associated with patellofemoral pain syndrome: a systematic review. Br J Sports Med. 2013;47(4):193–206.
pubmed: 22815424
doi: 10.1136/bjsports-2011-090369
Nagano Y, Naito K, Saho Y, Torii S, Ogata T, Nakazawa K, Akai M, Fukubayashi T. Association between in vivo knee kinematics during gait and the severity of knee osteoarthritis. Knee. 2012;19(5):628–32.
pubmed: 22192889
doi: 10.1016/j.knee.2011.11.002
Yocum D, Weinhandl JT, Fairbrother JT, Zhang S. Wide step width reduces knee abduction moment of obese adults during stair negotiation. J Biomech. 2018;75:138–46.
pubmed: 29776821
doi: 10.1016/j.jbiomech.2018.05.002
Hashimoto Y, Nishino K, Tomohiro T, Tsumoto S, Nakamura H. The remaining parameters of patellar instability could be affected for osteoarthritic change after medial patellofemoral ligament reconstruction with or without anteromedialization of the tibial tubercle osteotomy for patellar instability: a retrospective cohort study. BMC Musculoskelet Disord. 2023;24(1):56.
pubmed: 36683021
pmcid: 9869604
doi: 10.1186/s12891-022-06100-3
Wheatley MGA, Rainbow MJ, Clouthier AL. Patellofemoral mechanics: a review of Pathomechanics and Research Approaches. Curr Rev Musculoskelet Med. 2020;13(3):326–37.
pubmed: 32394363
pmcid: 7251040
doi: 10.1007/s12178-020-09626-y
Hunt MA, Birmingham TB, Giffin JR, Jenkyn TR. Associations among knee adduction moment, frontal plane ground reaction force, and lever arm during walking in patients with knee osteoarthritis. J Biomech. 2006;39(12):2213–20.
pubmed: 16168997
doi: 10.1016/j.jbiomech.2005.07.002
Costello KE, Felson DT, Neogi T, Segal NA, Lewis CE, Gross KD, Nevitt MC, Lewis CL, Kumar D. Ground reaction force patterns in knees with and without radiographic osteoarthritis and pain: descriptive analyses of a large cohort (the Multicenter Osteoarthritis Study). Osteoarthritis Cartilage. 2021;29(8):1138–46.
pubmed: 33757856
pmcid: 8319033
doi: 10.1016/j.joca.2021.03.009
Ruggeri M, Gill HS, Leardini A, Zaffagnini S, MacLeod A, Ortolani M, Faccia F, Grassi A, Fabbro GD, Durante S, et al. Superimposition of ground reaction force on tibial-plateau supporting diagnostics and post-operative evaluations in high-tibial osteotomy. A novel methodology. Gait Posture. 2022;94:144–52.
pubmed: 35334334
doi: 10.1016/j.gaitpost.2022.02.028
Zeng CY, Zhang ZR, Tang ZM, Hua FZ. Benefits and mechanisms of Exercise training for knee osteoarthritis. Front Physiol. 2021;12:794062.
pubmed: 34975542
pmcid: 8716769
doi: 10.3389/fphys.2021.794062
Boyer KA, Angst MS, Asay J, Giori NJ, Andriacchi TP. Sensitivity of gait parameters to the effects of anti-inflammatory and opioid treatments in knee osteoarthritis patients. J Orthop Res. 2012;30(7):1118–24.
pubmed: 22179861
doi: 10.1002/jor.22037
Bedson J, Croft PR. The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature. BMC Musculoskelet Disord. 2008;9:116.
pubmed: 18764949
pmcid: 2542996
doi: 10.1186/1471-2474-9-116