Managing vitreoretinal complications in uveal melanoma: Surgical treatment and practical considerations.

Choroidal melanoma endoresection ocular oncology onco-VR retinal detachment toxic tumour syndrome; vitreous hemorrhage vitreoretinal surgery

Journal

Seminars in ophthalmology
ISSN: 1744-5205
Titre abrégé: Semin Ophthalmol
Pays: England
ID NLM: 8610759

Informations de publication

Date de publication:
28 Aug 2024
Historique:
medline: 28 8 2024
pubmed: 28 8 2024
entrez: 28 8 2024
Statut: aheadofprint

Résumé

In the past few decades, the primary management for uveal melanoma has evolved from enucleation to eye-preserving treatments. However, despite achieving a high rate of local tumour control, complications following eye-preserving treatments still occur and are partly responsible for functional loss and secondary enucleation. A literature review by a broad international panel. We summarised the current literature on utilizing vitreoretinal (VR) surgery for managing the complications of uveal melanoma. We also provided insights from the authors' personal experience and practical recommendations for clinical care. With the advancement of VR instruments and surgical techniques and the combination of VR and ocular oncology knowledge ("Onco-VR"), it is now possible to manage or even prevent complications such as vitreous haemorrhage, retinal detachment, and toxic tumour syndrome.

Sections du résumé

BACKGROUND UNASSIGNED
In the past few decades, the primary management for uveal melanoma has evolved from enucleation to eye-preserving treatments. However, despite achieving a high rate of local tumour control, complications following eye-preserving treatments still occur and are partly responsible for functional loss and secondary enucleation.
METHODS UNASSIGNED
A literature review by a broad international panel.
RESULTS UNASSIGNED
We summarised the current literature on utilizing vitreoretinal (VR) surgery for managing the complications of uveal melanoma. We also provided insights from the authors' personal experience and practical recommendations for clinical care.
CONCLUSIONS UNASSIGNED
With the advancement of VR instruments and surgical techniques and the combination of VR and ocular oncology knowledge ("Onco-VR"), it is now possible to manage or even prevent complications such as vitreous haemorrhage, retinal detachment, and toxic tumour syndrome.

Identifiants

DOI: 10.1080/08820538.2024.2381774 PMID: 39194361
pubmed: 39194361
doi: 10.1080/08820538.2024.2381774
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-10

Auteurs

Rodrigo Anguita (R)

Department of Ophthalmology, Inselspital, University Hospital of Bern, Bern, Switzerland.
NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.

Hung-Da Chou (HD)

NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.
Chang Gung Memorial Hospital, Linkou Main Branch, Taoyuan, Taiwan.
College of Medicine, Chang Gung University, Taoyuan, Taiwan.
ORCID: 0000-0002-1561-3059

Vishal R Raval (VR)

Vitreoretina and ocular oncology, Anant Bajaj Retina Institute, L V Prasad Eye Institute, Hyderabad, India.

Vidhi Bajpai (V)

Vitreoretina and ocular oncology, Anant Bajaj Retina Institute, L V Prasad Eye Institute, Hyderabad, India.

Lorenzo Ferro Desideri (L)

Department of Ophthalmology, Inselspital, University Hospital of Bern, Bern, Switzerland.

Enrico Bernardi (E)

Department of Ophthalmology, Inselspital, University Hospital of Bern, Bern, Switzerland.

Rumana N Hussain (RN)

Liverpool Ocular Oncology Service, St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.

Min Kim (M)

Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Adrian T Fung (AT)

Westmead and Central (Save Sight Institute) Clinical Schools, Specialty of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, Australia.
Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.

Basil K Williams (BK)

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.

Maura Di Nicola (M)

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.

Mandeep S Sagoo (MS)

NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.

Lyndon da Cruz (L)

NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.

Bertil Damato (B)

NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.

Jens Folke Kiilgaard (JF)

Department of Ophthalmology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.
Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

Classifications MeSH