Enhanced ECCD36 Signaling Promotes Skeletal Muscle Insulin Resistance in Female Mice.
CD36
endothelial cells
insulin resistance
obesity
skeletal muscle
Journal
American journal of physiology. Endocrinology and metabolism
ISSN: 1522-1555
Titre abrégé: Am J Physiol Endocrinol Metab
Pays: United States
ID NLM: 100901226
Informations de publication
Date de publication:
28 Aug 2024
28 Aug 2024
Historique:
medline:
29
8
2024
pubmed:
29
8
2024
entrez:
28
8
2024
Statut:
aheadofprint
Résumé
Consumption of a Western diet (WD) increases CD36 expression in vascular, hepatic, and skeletal muscle tissues promoting lipid metabolic disorders and insulin resistance. We further examined the role of endothelial cell specific CD36 (ECCD36) signaling in contributing to skeletal muscle lipid metabolic disorders, insulin resistance, and their underlying molecular mechanisms. Female ECCD36 wild type (ECCD36
Identifiants
pubmed: 39196801
doi: 10.1152/ajpendo.00246.2024
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ID : DK124329
Organisme : HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI)
ID : HL172875
Organisme : U.S. Department of Veterans Affairs (VA)
ID : BX003391
Organisme : U.S. Department of Veterans Affairs (VA)
ID : 5101BX001981