Tuberculosis in otherwise healthy adults with inherited TNF deficiency.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
28 Aug 2024
Historique:
received: 07 01 2024
accepted: 22 07 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 28 8 2024
Statut: aheadofprint

Résumé

Severe defects in human IFNγ immunity predispose individuals to both Bacillus Calmette-Guérin disease and tuberculosis, whereas milder defects predispose only to tuberculosis

Identifiants

pubmed: 39198650
doi: 10.1038/s41586-024-07866-3
pii: 10.1038/s41586-024-07866-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Andrés A Arias (AA)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.
School of Microbiology, University of Antioquia UdeA, Medellín, Colombia.
St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Anna-Lena Neehus (AL)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France. anna-lena.neehus@childrens.harvard.edu.
Paris Cité University, Imagine Institute, Paris, France. anna-lena.neehus@childrens.harvard.edu.

Masato Ogishi (M)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Vincent Meynier (V)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Adam Krebs (A)

Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, NY, USA.

Tomi Lazarov (T)

Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, NY, USA.

Angela M Lee (AM)

Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, NY, USA.
Department of Microbiology & Immunology, Weill Cornell Medicine, New York, NY, USA.

Carlos A Arango-Franco (CA)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Rui Yang (R)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Julio Orrego (J)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Melissa Corcini Berndt (M)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Julian Rojas (J)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Hailun Li (H)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Darawan Rinchai (D)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Lucia Erazo-Borrás (L)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Ji Eun Han (JE)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Bethany Pillay (B)

Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.
School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Kensington, New South Wales, Australia.

Khoren Ponsin (K)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Matthieu Chaldebas (M)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Paris Cité University, Imagine Institute, Paris, France.

Quentin Philippot (Q)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Jonathan Bohlen (J)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Jérémie Rosain (J)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.
Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, Assistance publique-Hôpitaux de Paris (AP-HP), Paris, France.

Tom Le Voyer (T)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.
Clinical Immunology Department, AP-HP, Saint-Louis Hospital, Paris, France.

Till Janotte (T)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Krishnajina Amarajeeva (K)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Camille Soudée (C)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Marion Brollo (M)

Lab VIM Suresnes, UMR 0892, Paris Saclay University, INRAe UVSQ, Suresnes, France.

Katja Wiegmann (K)

Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Quentin Marquant (Q)

Lab VIM Suresnes, UMR 0892, Paris Saclay University, INRAe UVSQ, Suresnes, France.

Yoann Seeleuthner (Y)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Danyel Lee (D)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Candice Lainé (C)

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Doreen Kloos (D)

Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
REBIRTH-Research Center for Translational Regenerative Medicine, Hannover, Germany.

Rasheed Bailey (R)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Paul Bastard (P)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.
Pediatric Immunology-Hematology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.

Narelle Keating (N)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia.

Franck Rapaport (F)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Taushif Khan (T)

The Jackson Laboratory, Farmington, CT, USA.

Marcela Moncada-Vélez (M)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.
St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

María Camila Carmona (MC)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Catalina Obando (C)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Jesús Alvarez (J)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Juan Carlos Cataño (JC)

Infectious Diseases Section, Department of Internal Medicine, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Larry Luber Martínez-Rosado (LL)

Latin American Research Team in Infectiology and Public Health (ELISAP), La Maria Hospital, Medellín, Colombia.

Juan P Sanchez (JP)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Manuela Tejada-Giraldo (M)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Anne-Sophie L'Honneur (AS)

Department of Virology, Paris Cité University and Cochin Hospital, AP-HP, Paris, France.

María L Agudelo (ML)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Lizet J Perez-Zapata (LJ)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Diana M Arboleda (DM)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Juan Fernando Alzate (JF)

National Center for Genome Sequencing (CNSG), School of Medicine, University of Antioquia UdeA, Medellín, Colombia.

Felipe Cabarcas (F)

National Center for Genome Sequencing (CNSG), School of Medicine, University of Antioquia UdeA, Medellín, Colombia.
SISTEMIC Group, Department of Electronic Engineering, Faculty of Engineering, University of Antioquia UdeA, Medellín, Colombia.

Alejandra Zuluaga (A)

Corporation for Biological Research (CIB), Medellín, Colombia.

Simon J Pelham (SJ)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.

Armin Ensser (A)

University Hospital Erlangen, Institute of Virology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

Monika Schmidt (M)

University Hospital Erlangen, Institute of Virology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

Margarita M Velásquez-Lopera (MM)

Dermatology Section, Department of Internal Medicine, School of Medicine, University of Antioquia UdeA, Medellín, Colombia.
Dermatological Research Center (CIDERM), Medellín, Colombia.

Emmanuelle Jouanguy (E)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Anne Puel (A)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Martin Krönke (M)

Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.

Stefano Ghirardello (S)

Neonatal Intensive Care Unit, San Matteo Research Hospital, Pavia, Italy.

Alessandro Borghesi (A)

Neonatal Intensive Care Unit, San Matteo Research Hospital, Pavia, Italy.
School of Life Sciences, Swiss Federal Institute of Technology, Lausanne, Switzerland.

Susanta Pahari (S)

Host Pathogen Interactions program, Texas Biomedical Research Institute, San Antonio, TX, USA.

Bertrand Boisson (B)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Stefania Pittaluga (S)

Center for Cancer Research, Laboratory of Pathology, NCI, NIH, Bethesda, MD, USA.

Cindy S Ma (CS)

Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.
School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Kensington, New South Wales, Australia.

Jean-François Emile (JF)

Department of Pathology, Ambroise Paré Hospital, AP-HP, Boulogne-Billancourt, France.

Luigi D Notarangelo (LD)

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.

Stuart G Tangye (SG)

Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.
School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Kensington, New South Wales, Australia.

Nico Marr (N)

Department of Human Immunology, Sidra Medicine, Doha, Qatar.
College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.

Nico Lachmann (N)

Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.
REBIRTH-Research Center for Translational Regenerative Medicine, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Hannover, Germany.
Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.

Hélène Salvator (H)

Clinical Immunology Department, AP-HP, Saint-Louis Hospital, Paris, France.
Respiratory Diseases Department, FOCH Hospital, Suresnes, France.
Simone Veil Department of Health Sciences, Versailles Saint Quentin University, Montigny le Bretonneux, France.

Larry S Schlesinger (LS)

Host Pathogen Interactions program, Texas Biomedical Research Institute, San Antonio, TX, USA.

Peng Zhang (P)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Michael S Glickman (MS)

Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, NY, USA.

Carl F Nathan (CF)

Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, NY, USA.
Department of Microbiology & Immunology, Weill Cornell Medicine, New York, NY, USA.

Frédéric Geissmann (F)

Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, NY, USA.

Laurent Abel (L)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

José Luis Franco (JL)

Inborn Errors of Immunity Group, Department of Microbiology and Parasitology, School of Medicine, University of Antioquia UdeA, Medellín, Colombia. jose.franco@udea.edu.co.

Jacinta Bustamante (J)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.
Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, Assistance publique-Hôpitaux de Paris (AP-HP), Paris, France.

Jean-Laurent Casanova (JL)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA. casanova@mail.rockefeller.edu.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France. casanova@mail.rockefeller.edu.
Paris Cité University, Imagine Institute, Paris, France. casanova@mail.rockefeller.edu.
Howard Hughes Medical Institute, New York, NY, USA. casanova@mail.rockefeller.edu.
Department of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France. casanova@mail.rockefeller.edu.

Stéphanie Boisson-Dupuis (S)

St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY, USA.
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Paris Cité University, Imagine Institute, Paris, France.

Classifications MeSH