Individually tailored exercise in patients with postural orthostatic tachycardia syndrome related to post-COVID-19 condition - a feasibility study.

Humans Postural Orthostatic Tachycardia Syndrome / therapy Female Male COVID-19 / complications Feasibility Studies Adult Exercise Therapy / methods Middle Aged Quality of Life Post-Acute COVID-19 Syndrome Exercise SARS-CoV-2 / isolation & purification Resistance Training / methods Surveys and Questionnaires

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
28 Aug 2024
Historique:
received: 26 02 2024
accepted: 22 08 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 28 8 2024
Statut: epublish

Résumé

Postural orthostatic tachycardia syndrome (POTS) occurs in approximately 30% of people with highly symptomatic post-COVID-19 condition (PCC). It involves several symptoms that limit physical and psychological functions and cause reduced quality of life. Evidence for different treatments of POTS and PCC is limited, and this study aimed to evaluate the feasibility of individually tailored physical exercise. The secondary aim of the study was to evaluate the preliminary effectiveness of this intervention. Twenty-six participants (81% female, median age 41 years) were enrolled and performed individually tailored endurance and strength training, with progression, for twelve weeks. During the intervention period, the participants had weekly support from a physiotherapist. Feasibility was evaluated with good compliance, with 76% adherence to exercise prescription and 96% completing the study protocol. The treatment was safe, and the evaluation methods (questionnaires, physical assessments, and accelerometer monitoring) were judged to be feasible. After the intervention, improvements in symptom burden as well as in psychological and physical functions were observed. In conclusion, future randomized controlled trials can be performed with only minor adjustments and could include questionnaires, physical assessment and accelerometer monitoring, which were demonstrated as feasible by this study.

Identifiants

DOI: 10.1038/s41598-024-71055-5 PMID: 39198662
pubmed: 39198662
doi: 10.1038/s41598-024-71055-5
pii: 10.1038/s41598-024-71055-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20017

Subventions

Organisme : Vetenskapsrådet (Swedish Research Council)
ID : 2021-02844
Organisme : Hjärt-Lungfonden (Swedish Heart-Lung Foundation)
ID : 20210024
Organisme : Hjärt-Lungfonden (Swedish Heart-Lung Foundation)
ID : 20210539

Informations de copyright

© 2024. The Author(s).

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Auteurs

Annie Svensson (A)

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. annie.svensson@ki.se.
Medical Unit Allied Health Professionals, Women's Health and Allied Health Professionals Theme, Karolinska University Hospital, Stockholm, Sweden. annie.svensson@ki.se.

Anna Svensson-Raskh (A)

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Medical Unit Allied Health Professionals, Women's Health and Allied Health Professionals Theme, Karolinska University Hospital, Stockholm, Sweden.

Linda Holmström (L)

Medical Unit Allied Health Professionals, Women's Health and Allied Health Professionals Theme, Karolinska University Hospital, Stockholm, Sweden.
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Carl Hallberg (C)

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Medical Unit Allied Health Professionals, Women's Health and Allied Health Professionals Theme, Karolinska University Hospital, Stockholm, Sweden.

Lucian Bezuidenhout (L)

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Division of Physiotherapy, Department of Health and Rehabilitation Sciences, Stellenbosch University, Cape Town, South Africa.

David Moulaee Conradsson (D)

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Medical Unit Allied Health Professionals, Women's Health and Allied Health Professionals Theme, Karolinska University Hospital, Stockholm, Sweden.

Marcus Ståhlberg (M)

Department of Medicine, Karolinska Institutet, Solna, Sweden.
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.

Judith Bruchfeld (J)

Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
Division of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

Artur Fedorowski (A)

Department of Medicine, Karolinska Institutet, Solna, Sweden.
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.

Malin Nygren-Bonnier (M)

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Medical Unit Allied Health Professionals, Women's Health and Allied Health Professionals Theme, Karolinska University Hospital, Stockholm, Sweden.

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Classifications MeSH

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