Investigating the Antimicrobial Potential of 560 Compounds from the Pandemic Response Box and COVID Box against Resistant Gram-Negative Bacteria.

Gram-negative bacteria antimicrobial resistance drug screening multidrug-resistant resistance

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
01 Aug 2024
Historique:
received: 19 06 2024
revised: 25 07 2024
accepted: 26 07 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 29 8 2024
Statut: epublish

Résumé

Antimicrobial resistance (AMR) has emerged as a significant threat to public health, particularly in infections caused by critically important Gram-negative bacteria. The development of novel antibiotics has its limitations, and therefore it is crucial to explore alternative strategies to effectively combat infections with resistant pathogens. In this context, the present study investigated the antibacterial potency of 560 compounds against the multidrug-resistant (MDR) strains of

Identifiants

pubmed: 39200023
pii: antibiotics13080723
doi: 10.3390/antibiotics13080723
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : National Council for Scientific and Technological Development
ID : Subsídios 408778/2022-9, 307946/2022-3, 420743/2023-5 e 444735/2023-2;
Organisme : Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul
ID : under Grants 76/2023 and 113/2023

Auteurs

Rita de Cássia Cerqueira Melo (RC)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Aline Andrade Martins (AA)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Andressa Leite Ferraz Melo (ALF)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Jean Carlos Pael Vicente (JCP)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Mariana Carvalho Sturaro (MC)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Julia Pimentel Arantes (JP)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Luana Rossato (L)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Gleyce Hellen de Almeida de Souza (GHA)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Simone Simionatto (S)

Health Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.

Classifications MeSH