Antimicrobial Efficacy of Chemomechanical Carie Removal Agents-A Systematic Integrative Review.

antimicrobial efficacy chemomechanical caries removal system dental caries minimal invasive

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
02 Aug 2024
Historique:
received: 28 06 2024
revised: 28 07 2024
accepted: 31 07 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 29 8 2024
Statut: epublish

Résumé

Dental caries is the most common oral disease in the world. When treatable, the drilling method continues to be used. This technique has its disadvantages because it is invasive and nonspecific. Chemomechanical carious tissue removal agents (CCRAs) such as Carisolv™ or Papacarie The aim is to analyze whether CCRAs have a relevant antimicrobial effect on cariogenic bacteria. A bibliographic search strategy was carried out in online databases using PRISMA 2020. The evaluation of the antibacterial efficacy of CCRAs was carried out through the analysis of the reduction in CFUs of cariogenic bacteria, and the presence of bacterial deposits, TVC, SVC and LVC by comparison with conventional drilling methods. The results showed that the percentage of reduction in TVC, SVC and LVC for each agent is mostly high, but not significantly different from mechanical methods. The best results were found with CCRAs when compared to polymeric drills. The results also showed that there is a lack of methodological standardization. CCRAs have been shown to have a relevant antimicrobial effect on cariogenic bacteria; however, more studies need to be carried out using standardized methodologies.

Sections du résumé

BACKGROUND BACKGROUND
Dental caries is the most common oral disease in the world. When treatable, the drilling method continues to be used. This technique has its disadvantages because it is invasive and nonspecific. Chemomechanical carious tissue removal agents (CCRAs) such as Carisolv™ or Papacarie
OBJECTIVES OBJECTIVE
The aim is to analyze whether CCRAs have a relevant antimicrobial effect on cariogenic bacteria.
METHODS METHODS
A bibliographic search strategy was carried out in online databases using PRISMA 2020. The evaluation of the antibacterial efficacy of CCRAs was carried out through the analysis of the reduction in CFUs of cariogenic bacteria, and the presence of bacterial deposits, TVC, SVC and LVC by comparison with conventional drilling methods.
RESULTS RESULTS
The results showed that the percentage of reduction in TVC, SVC and LVC for each agent is mostly high, but not significantly different from mechanical methods. The best results were found with CCRAs when compared to polymeric drills. The results also showed that there is a lack of methodological standardization.
CONCLUSIONS CONCLUSIONS
CCRAs have been shown to have a relevant antimicrobial effect on cariogenic bacteria; however, more studies need to be carried out using standardized methodologies.

Identifiants

pubmed: 39200199
pii: biomedicines12081735
doi: 10.3390/biomedicines12081735
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Auteurs

Adélaïde Janvier (A)

Dental Sciences, University Institute of Health Sciences (IUCS-CESPU), 4585-116 Gandra, Portugal.

Marie Maziere (M)

UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS-CESPU), 4585-116 Gandra, Portugal.

Célia F Rodrigues (CF)

Associate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, Avenida Central de Gandra 1317, 4585-116 Gandra, Portugal.
UCIBIO-Applied Molecular Biosciences Unit, Translational Toxicology Research Laboratory, University Institute of Health Sciences (1H-TOXRUN, IUCS-CESPU), 4585-116 Porto, Portugal.
LEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, University of Porto, 4200-465 Porto, Portugal.

Ana Paula Lobo (AP)

Dental Sciences, University Institute of Health Sciences (IUCS-CESPU), 4585-116 Gandra, Portugal.

Paulo Rompante (P)

UNIPRO-Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS-CESPU), 4585-116 Gandra, Portugal.

Classifications MeSH