Increased Homer Activity and NMJ Localization in the Vestibular Lesion

Animals Homer Scaffolding Proteins / metabolism Mice Muscle, Skeletal / metabolism Neuromuscular Junction / metabolism Mice, Knockout Male Vestibular Diseases / metabolism Protein Isoforms / metabolism
Homer NMJ vestibular lesion

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
06 Aug 2024
Historique:
received: 28 06 2024
revised: 27 07 2024
accepted: 02 08 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 29 8 2024
Statut: epublish

Résumé

We investigated the shuttling of Homer protein isoforms identified in soluble (cytosolic) vs. insoluble (membrane-cytoskeletal) fraction and Homer protein-protein interaction/activation in the deep postural calf

Identifiants

DOI: 10.3390/ijms25168577 PMID: 39201265
pubmed: 39201265
pii: ijms25168577
doi: 10.3390/ijms25168577
pii:
doi:

Substances chimiques

Homer Scaffolding Proteins 0
Protein Isoforms 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Federal Ministry for Economic Affairs and Climate Action (BMWK) through Deutsches Zentrum fuer Luft- und Raumfahrt (DLR e.V., Bonn-Oberkassel, Germany)
ID : 50WB0521-0821-1121-1421 (to D.B.)

Auteurs

Gabor Trautmann (G)

Institute of Integrative Neuroanatomy, Neuromuscular Signaling and System, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115 Berlin, Germany.
Center of Space Medicine Berlin, 10115 Berlin, Germany.
ORCID: 0000-0002-8917-2962

Katharina Block (K)

Institute of Integrative Neuroanatomy, Neuromuscular Signaling and System, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115 Berlin, Germany.
Center of Space Medicine Berlin, 10115 Berlin, Germany.
ORCID: 0000-0002-2752-5232

Martina Gutsmann (M)

Institute of Integrative Neuroanatomy, Neuromuscular Signaling and System, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115 Berlin, Germany.

Stéphane Besnard (S)

UR VERTEX 7480, CHU de Caen, Université de Caen Normandie, 10115 Caen, France.

Sandra Furlan (S)

C.N.R. Institute of Neuroscience, 14000 Padova, Italy.

Pierre Denise (P)

COMETE U1075, INSERM, CYCERON, CHU de Caen, Normandie Université, Université de Caen Normandie, 10115 Caen, France.
ORCID: 0000-0002-9049-7692

Pompeo Volpe (P)

Department of Biomedical Sciences, University of Padova, 14000 Padova, Italy.
ORCID: 0000-0003-0151-1585

Dieter Blottner (D)

Institute of Integrative Neuroanatomy, Neuromuscular Signaling and System, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115 Berlin, Germany.
Center of Space Medicine Berlin, 10115 Berlin, Germany.
ORCID: 0000-0003-0355-3340

Michele Salanova (M)

Institute of Integrative Neuroanatomy, Neuromuscular Signaling and System, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115 Berlin, Germany.
Center of Space Medicine Berlin, 10115 Berlin, Germany.
ORCID: 0000-0002-7066-3876

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Increased Homer Activity and NMJ Localization...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › Protéines d'échafaudage Homer › Increased Homer Activity and NMJ Localization...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Increased Homer Activity and NMJ Localization...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Muscles squelettiques › Increased Homer Activity and NMJ Localization...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Structures de la membrane cellulaire › Jonctions intercellulaires › Synapses › Synapse neuro-effectrice › Jonction neuromusculaire › Increased Homer Activity and NMJ Localization...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Increased Homer Activity and NMJ Localization...
questionsmedicales.fr › Maladies oto-rhino-laryngologiques › Maladies des oreilles › Maladies labyrinthiques › Maladies vestibulaires › Increased Homer Activity and NMJ Localization...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Isoformes de protéines › Increased Homer Activity and NMJ Localization...