Molecular Basis of Hydatidiform Moles-A Systematic Review.

Humans Hydatidiform Mole / genetics Pregnancy Female MicroRNAs / genetics Uterine Neoplasms / genetics Epigenesis, Genetic
choriocarcinoma complete molar pregnancy gestational trophoblastic disease hydatidiform mole molecular basis of molar pregnancy partial molar pregnancy

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
10 Aug 2024
Historique:
received: 06 07 2024
revised: 02 08 2024
accepted: 07 08 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 29 8 2024
Statut: epublish

Résumé

Gestational trophoblastic diseases (GTDs) encompass a spectrum of conditions characterized by abnormal trophoblastic cell growth, ranging from benign molar pregnancies to malignant trophoblastic neoplasms. This systematic review explores the molecular underpinnings of GTDs, focusing on genetic and epigenetic factors that influence disease progression and clinical outcomes. Based on 71 studies identified through systematic search and selection criteria, key findings include dysregulations in tumor suppressor genes such as

Identifiants

DOI: 10.3390/ijms25168739 PMID: 39201425
pubmed: 39201425
pii: ijms25168739
doi: 10.3390/ijms25168739
pii:
doi:

Substances chimiques

MicroRNAs 0

Types de publication

Systematic Review Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Shadha Nasser Mohammed Bahutair (SNM)

Department of Obstetrics and Gynecology, RAK College of Medical Sciences, RAK Medical & Health Sciences University, Ras al Khaimah P.O. Box 11172, United Arab Emirates.
ORCID: 0009-0002-6427-1355

Rajani Dube (R)

Department of Obstetrics and Gynecology, RAK College of Medical Sciences, RAK Medical & Health Sciences University, Ras al Khaimah P.O. Box 11172, United Arab Emirates.
ORCID: 0000-0002-1539-6162

Manjunatha Goud Bellary Kuruba (MGB)

Department of Biochemistry, RAK College of Medical Sciences, RAK Medical & Health Sciences University, Ras al Khaimah P.O. Box 11172, United Arab Emirates.
ORCID: 0000-0002-7195-6945

Rasha Aziz Attia Salama (RAA)

Department of Community Medicine, RAK College of Medical Sciences, RAK Medical & Health Sciences University, Ras al Khaimah P.O. Box 11172, United Arab Emirates.
Department of Public Health and Community Medicine, Kasr El Ainy Faculty of Medicine, Cairo University, Cairo 12613, Egypt.
ORCID: 0000-0002-1102-9306

Mohamed Anas Mohamed Faruk Patni (MAMF)

Department of Community Medicine, RAK College of Medical Sciences, RAK Medical & Health Sciences University, Ras al Khaimah P.O. Box 11172, United Arab Emirates.
ORCID: 0000-0001-6948-3619

Subhranshu Sekhar Kar (SS)

Department of Pediatrics, RAK College of Medical Sciences, RAK Medical & Health Sciences University, Ras al Khaimah P.O. Box 11172, United Arab Emirates.
ORCID: 0000-0002-9379-7447

Rakhee Kar (R)

Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry 605006, India.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Molecular Basis of Hydatidiform Moles-A...
questionsmedicales.fr › Maladies urogénitales › Maladies de l'appareil urogénital féminin et complications de la grossesse › Complications de la grossesse › Complications tumorales de la grossesse › Tumeurs trophoblastiques › Maladie trophoblastique gestationnelle › Môle hydatiforme › Molecular Basis of Hydatidiform Moles-A...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Molecular Basis of Hydatidiform Moles-A...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › microARN › Molecular Basis of Hydatidiform Moles-A...
questionsmedicales.fr › Maladies urogénitales › Tumeurs de l'appareil urogénital › Tumeurs de l'appareil génital féminin › Tumeurs de l'utérus › Molecular Basis of Hydatidiform Moles-A...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Molecular Basis of Hydatidiform Moles-A...