Sex as a Predictor of Outcomes for Symptomatic Carotid Stenosis: A Comparative Analysis between CAS and CEA.

carotid artery stenting carotid endarterectomy carotid revascularization female sex symptomatic carotid stenosis timing

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
05 Aug 2024
Historique:
received: 16 05 2024
revised: 25 07 2024
accepted: 29 07 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 29 8 2024
Statut: epublish

Résumé

Reporting gender-related outcomes for symptomatic carotid lesion revascularization after both endarterectomy (CEA) and carotid artery stenting (CAS) procedures in an unselected group of patients treated by Italian Vascular Specialists. A retrospective study was conducted on patients presenting with recently symptomatic carotid stenosis treated by CAS and by CEA. The primary endpoint was the 30 days any stroke occurrence rate; secondary endpoints were technical success, occurrence of transient ischemic attack (TIA), acute myocardial infarction (AMI) and death. Demographic, clinical and procedural data were all noted in order to identify the outcome's determining factor. A total of 265 patients (193 males and 72 females) were enrolled, and of these 134 (50.5%) underwent CEA and 131 CAS (49.5%). At 30 days, the overall new stroke rate was 3.4% (one fatal), and no TIA, AMI or deaths were observed. Among strokes, seven major and two minor strokes were reported, with six after CEA and three after CAS ( Our experience seems to suggest that both CEA and CAS provide safe and effective results in treating patients presenting with symptomatic carotid stenosis. Regardless of the type of revascularization, female sex is an independent risk factor for stroke recurrence after treatment.

Identifiants

pubmed: 39202021
pii: jpm14080830
doi: 10.3390/jpm14080830
pmc: PMC11355406
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Pasqualino Sirignano (P)

Vascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of General and Specialistic Surgery, "Sapienza" University of Rome, 00189 Rome, Italy.

Costanza Margheritini (C)

Vascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, Italy.

Wassim Mansour (W)

Vascular and Endovascular Surgery Unit, Policlinico Umberto I Hospital of Rome, Department of General and Specialistic Surgery, "Sapienza" University of Rome, 00161 Rome, Italy.

Francesco Aloisi (F)

Vascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, Italy.

Carlo Setacci (C)

Vascular and Endovascuar Surgery Unit, "Le Scotte" Hospital of Siena, Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.

Francesco Speziale (F)

Vascular and Endovascular Surgery Unit, Policlinico Umberto I Hospital of Rome, Department of General and Specialistic Surgery, "Sapienza" University of Rome, 00161 Rome, Italy.

Eugenio Stabile (E)

Division of Cardiology, Cardiovascular Department, San Carlo Regional Hospital, "Federico II" University of Naples, 85100 Potenza, Italy.

Maurizio Taurino (M)

Vascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, Italy.

Classifications MeSH