Receptors on Microglia.

Chemokines Cytokines DAMP Ion channels Microglia Neurotransmitter receptors PAMP Purinoceptors TLR

Journal

Advances in neurobiology
ISSN: 2190-5215
Titre abrégé: Adv Neurobiol
Pays: United States
ID NLM: 101571545

Informations de publication

Date de publication:
2024
Historique:
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 29 8 2024
Statut: ppublish

Résumé

Microglial cells are the most receptive cells in the central nervous system (CNS), expressing several classes of receptors reflecting their immune heritage and newly acquired neural specialisation. Microglia possess, depending on the particular context, receptors to neurotransmitters and neuromodulators as well as immunocompetent receptors. This rich complement allows microglial cells to monitor the functional status of the nervous system, contribute actively to the regulation of neural activity and plasticity and homeostasis, and guard against pathogens as well as other challenges to the CNS's integrity and function.

Identifiants

pubmed: 39207688
doi: 10.1007/978-3-031-55529-9_6
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

83-121

Informations de copyright

© 2024. The Author(s), under exclusive license to Springer Nature Switzerland AG.

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Auteurs

Marcus Augusto-Oliveira (M)

Laboratório de Farmacologia Molecular, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Brazil.
Programa de Pós-Graduação em Farmacologia e Bioquímica, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém, Brazil.

Marie-Ève Tremblay (MÈ)

Division of Medical Sciences, Medical Sciences Building, University of Victoria, Victoria, BC, Canada.
Axe neurosciences, Centre de recherche du CHU de Québec-Université Laval, Québec City, QC, Canada.
Neurology and Neurosurgery Department, McGill University, Montreal, QC, Canada.
Department of Molecular Medicine, Université Laval, Pavillon Ferdinand-Vandry, Québec City, QC, Canada.
Department of Biochemistry and Molecular Biology, The University of British Columbia, Life Sciences Center, Vancouver, BC, Canada.

Alexei Verkhratsky (A)

Faculty of Life Sciences, The University of Manchester, Manchester, UK. Alexej.Verkhratsky@manchester.ac.uk.
Department of Neurosciences, University of the Basque Country, Leioa, Spain. Alexej.Verkhratsky@manchester.ac.uk.
IKERBASQUE, Basque Foundation for Science, Bilbao, Spain. Alexej.Verkhratsky@manchester.ac.uk.

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