Five-year outcomes of measured and predicted prosthesis-patient mismatch following transcatheter aortic valve implantation.
Effective orifice area
measured prosthesis–patient mismatch
outcomes
predicted prosthesis–patient mismatch
transcatheter aortic valve replacement
Journal
The American journal of cardiology
ISSN: 1879-1913
Titre abrégé: Am J Cardiol
Pays: United States
ID NLM: 0207277
Informations de publication
Date de publication:
27 Aug 2024
27 Aug 2024
Historique:
received:
22
06
2024
accepted:
15
08
2024
medline:
31
8
2024
pubmed:
31
8
2024
entrez:
29
8
2024
Statut:
aheadofprint
Résumé
Data on the long-term outcomes of prosthesis-patient mismatch (PPM) after transcatheter aortic valve implantation (TAVI) remain controversial. The aim of this study was to investigate the incidence and clinical outcomes of measured PPM (PPM This is a retrospective analysis of 3,016 patients who underwent TAVI at a large Healthcare System between 2012 and 2021. Effective orifice area indexed to body surface area (EOAi) was measured at discharge using the continuity equation. EOAi was predicted according to the published predictive tables for each model and size of the valve. Primary endpoint was 5-year survival rate. Mean age was 80 years and 55.6% were male. The mean STS risk score was 4.66%. 74.9% of patients received a BEV and 25.1% received a SEV. The incidence of severe PPM was markedly lower when defined by predicted vs. measured EOAi (0.8% vs. 6.3%, P < 0.001) and when assessed in SEV vs. BEV (5.3% vs. 6.6%, p= 0.02). Neither severe PPM In this large healthcare system analysis, neither severe PPM
Sections du résumé
BACKGROUND
BACKGROUND
Data on the long-term outcomes of prosthesis-patient mismatch (PPM) after transcatheter aortic valve implantation (TAVI) remain controversial.
OBJECTIVES
OBJECTIVE
The aim of this study was to investigate the incidence and clinical outcomes of measured PPM (PPM
METHODS
METHODS
This is a retrospective analysis of 3,016 patients who underwent TAVI at a large Healthcare System between 2012 and 2021. Effective orifice area indexed to body surface area (EOAi) was measured at discharge using the continuity equation. EOAi was predicted according to the published predictive tables for each model and size of the valve. Primary endpoint was 5-year survival rate.
RESULTS
RESULTS
Mean age was 80 years and 55.6% were male. The mean STS risk score was 4.66%. 74.9% of patients received a BEV and 25.1% received a SEV. The incidence of severe PPM was markedly lower when defined by predicted vs. measured EOAi (0.8% vs. 6.3%, P < 0.001) and when assessed in SEV vs. BEV (5.3% vs. 6.6%, p= 0.02). Neither severe PPM
CONCLUSIONS
CONCLUSIONS
In this large healthcare system analysis, neither severe PPM
Identifiants
pubmed: 39209242
pii: S0002-9149(24)00604-0
doi: 10.1016/j.amjcard.2024.08.013
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024. Published by Elsevier Inc.