Medical management of chronic subdural hematoma with low-dose hydrocortisone: a case series.
Chronic
Glucocorticoids
Hematoma
Hydrocortisone
Subdural
Journal
Neurosurgical review
ISSN: 1437-2320
Titre abrégé: Neurosurg Rev
Pays: Germany
ID NLM: 7908181
Informations de publication
Date de publication:
30 Aug 2024
30 Aug 2024
Historique:
received:
09
05
2024
accepted:
23
08
2024
revised:
09
07
2024
medline:
31
8
2024
pubmed:
31
8
2024
entrez:
30
8
2024
Statut:
epublish
Résumé
Chronic subdural hematomas (cSDH) are often managed with a burr-hole craniostomy and drainage, but surgery is associated with elevated mortality, morbidity, and recurrence. Despite reports of steroid use for such patients, its efficacy and feasibility are still debated. We present our patient series treated with low-dose hydrocortisone. We retrospectively reviewed data from patients treated with hydrocortisone between 2017 and 2023. Demographics, clinical and radiological data were collected. Of 27 patients identified, nine required a burr-hole craniotomy for an average volume of 120.23 cm
Identifiants
pubmed: 39212781
doi: 10.1007/s10143-024-02763-9
pii: 10.1007/s10143-024-02763-9
doi:
Substances chimiques
Hydrocortisone
WI4X0X7BPJ
Anti-Inflammatory Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
509Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Edlmann E, Giorgi-Coll S, Whitfield PC, Carpenter KLH, Hutchinson PJ (2017) Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy. J Neuroinflammation 14(1):108
pmcid: 5450087
doi: 10.1186/s12974-017-0881-y
pubmed: 28558815
Glover D, Labadie EL (1976) Physiopathogenesis of subdural hematomas. Part 2: inhibition of growth of experimental hematomas with dexamethasone. J Neurosurg 45(4):393–397
doi: 10.3171/jns.1976.45.4.0393
pubmed: 956875
Hong HJ, Kim YJ, Yi HJ, Ko Y, Oh SJ, Kim JM (2009) Role of angiogenic growth factors and inflammatory cytokine on recurrence of chronic subdural hematoma. Surg Neurol 71(2):161–165 discussion 5–6
doi: 10.1016/j.surneu.2008.01.023
pubmed: 18423527
Almenawer SA, Farrokhyar F, Hong C, Alhazzani W, Manoranjan B, Yarascavitch B et al (2014) Chronic subdural hematoma management: a systematic review and meta-analysis of 34,829 patients. Ann Surg 259(3):449–457
doi: 10.1097/SLA.0000000000000255
pubmed: 24096761
Balser D, Farooq S, Mehmood T, Reyes M, Samadani U (2015) Actual and projected incidence rates for chronic subdural hematomas in United States Veterans Administration and civilian populations. J Neurosurg 123(5):1209–1215
pmcid: 4575892
doi: 10.3171/2014.9.JNS141550
pubmed: 25794342
Ducruet AF, Grobelny BT, Zacharia BE, Hickman ZL, DeRosa PL, Andersen KN et al (2012) The surgical management of chronic subdural hematoma. Neurosurg Rev 35(2):155–169 discussion 69
doi: 10.1007/s10143-011-0349-y
pubmed: 21909694
Miranda LB, Braxton E, Hobbs J, Quigley MR (2011) Chronic subdural hematoma in the elderly: not a benign disease. J Neurosurg 114(1):72–76
doi: 10.3171/2010.8.JNS10298
pubmed: 20868215
Rauhala M, Luoto TM, Huhtala H, Iverson GL, Niskakangas T, Ohman J, Helen P (2019) The incidence of chronic subdural hematomas from 1990 to 2015 in a defined Finnish population. J Neurosurg 132(4):1147–1157
doi: 10.3171/2018.12.JNS183035
pubmed: 30901751
Rodriguez B, Morgan I, Young T, Vlastos J, Williams T, Hrabarchuk EI et al (2023) Surgical techniques for evacuation of chronic subdural hematoma: a mini-review. Front Neurol 14:1086645
pmcid: 10338715
doi: 10.3389/fneur.2023.1086645
pubmed: 37456631
Sun TF, Boet R, Poon WS (2005) Non-surgical primary treatment of chronic subdural haematoma: preliminary results of using dexamethasone. Br J Neurosurg 19(4):327–333
doi: 10.1080/02688690500305332
pubmed: 16455539
Kolias AG, Chari A, Santarius T, Hutchinson PJ (2014) Chronic subdural haematoma: modern management and emerging therapies. Nat Rev Neurol 10(10):570–578
doi: 10.1038/nrneurol.2014.163
pubmed: 25224156
Mehta V, Harward SC, Sankey EW, Nayar G, Codd PJ (2018) Evidence based diagnosis and management of chronic subdural hematoma: a review of the literature. J Clin Neurosci 50:7–15
doi: 10.1016/j.jocn.2018.01.050
pubmed: 29428263
Ban SP, Hwang G, Byoun HS, Kim T, Lee SU, Bang JS et al (2018) Middle meningeal artery embolization for chronic subdural hematoma. Radiology 286(3):992–999
doi: 10.1148/radiol.2017170053
pubmed: 29019449
Brennan PM, Kolias AG, Joannides AJ, Shapey J, Marcus HJ, Gregson BA et al (2017) The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom. J Neurosurg 127(4):732–739
doi: 10.3171/2016.8.JNS16134
pubmed: 27834599
Holl DC, Volovici V, Dirven CMF, van Kooten F, Miah IP, Jellema K et al (2019) Corticosteroid treatment compared with surgery in chronic subdural hematoma: a systematic review and meta-analysis. Acta Neurochir (Wien) 161(6):1231–1242
doi: 10.1007/s00701-019-03881-w
pubmed: 30972566
Knopman J, Link TW, Navi BB, Murthy SB, Merkler AE, Kamel H (2018) Rates of repeated operation for isolated subdural hematoma among older adults. JAMA Netw Open 1(6):e183737
pmcid: 6324600
doi: 10.1001/jamanetworkopen.2018.3737
pubmed: 30646255
Rovlias A, Theodoropoulos S, Papoutsakis D (2015) Chronic subdural hematoma: Surgical management and outcome in 986 cases: a classification and regression tree approach. Surg Neurol Int 6:127
pmcid: 4524005
doi: 10.4103/2152-7806.161788
pubmed: 26257985
Al-Mefty O (2023) Varieties of chronic subdural hematoma and glucocorticoid treatment. N Engl J Med 388(24):2289–2290
doi: 10.1056/NEJMe2304797
pubmed: 37314710
Bender MB, Christoff N (1974) Nonsurgical treatment of subdural hematomas. Arch Neurol 31(2):73–79
doi: 10.1001/archneur.1974.00490380021001
pubmed: 4834968
Berghauser Pont LM, Dirven CM, Dippel DW, Verweij BH, Dammers R (2012) The role of corticosteroids in the management of chronic subdural hematoma: a systematic review. Eur J Neurol 19(11):1397–1403
doi: 10.1111/j.1468-1331.2012.03768.x
pubmed: 22642223
Prud’homme M, Mathieu F, Marcotte N, Cottin S (2016) A pilot placebo controlled Randomized Trial of Dexamethasone for Chronic Subdural Hematoma. Can J Neurol Sci 43(2):284–290
doi: 10.1017/cjn.2015.393
pubmed: 26853325
Harput MV, Gonzalez-Lopez P, Ture U (2014) Three-dimensional reconstruction of the topographical cerebral surface anatomy for presurgical planning with free OsiriX Software. Neurosurgery. 10 Suppl 3:426 – 35; discussion 35.
Markwalder TM, Steinsiepe KF, Rohner M, Reichenbach W, Markwalder H (1981) The course of chronic subdural hematomas after burr-hole craniostomy and closed-system drainage. J Neurosurg 55(3):390–396
doi: 10.3171/jns.1981.55.3.0390
pubmed: 7264730
Ivamoto HS, Lemos HP Jr., Atallah AN (2016) Surgical treatments for chronic subdural hematomas: a comprehensive systematic review. World Neurosurg 86:399–418
doi: 10.1016/j.wneu.2015.10.025
pubmed: 26485412
Weigel R, Schmiedek P, Krauss JK (2003) Outcome of contemporary surgery for chronic subdural haematoma: evidence based review. J Neurol Neurosurg Psychiatry 74(7):937–943
pmcid: 1738576
doi: 10.1136/jnnp.74.7.937
pubmed: 12810784
Decaux O, Cador B, Dufour T, Jégo P, Cazalets C, Laurat E, Grosbois B (2002) [Nonsurgical treatment of chronic subdural hematoma with steroids: two case reports]. Rev Med Interne 23(9):788–791
doi: 10.1016/S0248-8663(02)00676-8
pubmed: 12378833
Delgado-López PD, Martín-Velasco V, Castilla-Díez JM, Rodríguez-Salazar A, Galacho-Harriero AM, Fernández-Arconada O (2009) Dexamethasone treatment in chronic subdural haematoma. Neurocirugia (Astur) 20(4):346–359
doi: 10.1016/S1130-1473(09)70154-X
pubmed: 19688136
Ommaya AK, Yarnell P (1969) Subdural haematoma after whiplash injury. Lancet 2(7614):237–239
pubmed: 4184108
Gelabert-Gonzalez M, Iglesias-Pais M, Garcia-Allut A, Martinez-Rumbo R (2005) Chronic subdural haematoma: surgical treatment and outcome in 1000 cases. Clin Neurol Neurosurg 107(3):223–229
doi: 10.1016/j.clineuro.2004.09.015
pubmed: 15823679
Stroobandt G, Fransen P, Thauvoy C, Menard E (1995) Pathogenetic factors in chronic subdural haematoma and causes of recurrence after drainage. Acta Neurochir (Wien) 137(1–2):6–14
doi: 10.1007/BF02188772
pubmed: 8748860
D’Abbondanza JA, Loch Macdonald R (2014) Experimental models of chronic subdural hematoma. Neurol Res 36(2):176–188
doi: 10.1179/1743132813Y.0000000279
pubmed: 24172841
Gurses ME, Bahadir S, Bilginer B (2022) Traumatic subgaleal hematoma in patient with Ehlers-Danlos syndrome: a rare case report. Surg Neurol Int 13:265
pmcid: 9282823
doi: 10.25259/SNI_186_2022
pubmed: 35855180
Inglis K (1946) Subdural haemorrhage, cysts and false membranes; illustrating the influence of intrinsic factors in disease when development of the body is normal. Brain 69(3):157–194
doi: 10.1093/brain/69.3.157
pubmed: 20285677
Sajanti J, Majamaa K (2003) High concentrations of procollagen propeptides in chronic subdural haematoma and effusion. J Neurol Neurosurg Psychiatry 74(4):522–524
pmcid: 1738388
doi: 10.1136/jnnp.74.4.522
pubmed: 12640081
Virchow (1858) The Pathology of miners’ lung. Edinb Med J 4(3):204–213
pmcid: 5309051
pubmed: 29646619
Heula AL, Sajanti J, Majamaa K (2009) Procollagen propeptides in chronic subdural hematoma reveal sustained dural collagen synthesis after head injury. J Neurol 256(1):66–71
doi: 10.1007/s00415-009-0048-6
pubmed: 19221848
Yamashima T, Yamamoto S, Friede RL (1983) The role of endothelial gap junctions in the enlargement of chronic subdural hematomas. J Neurosurg 59(2):298–303
doi: 10.3171/jns.1983.59.2.0298
pubmed: 6864298
Kawakami Y, Chikama M, Tamiya T, Shimamura Y (1989) Coagulation and fibrinolysis in chronic subdural hematoma. Neurosurgery 25(1):25–29
doi: 10.1227/00006123-198907000-00005
pubmed: 2755576
Hara M, Tamaki M, Aoyagi M, Ohno K (2009) Possible role of cyclooxygenase-2 in developing chronic subdural hematoma. J Med Dent Sci 56(3):101–106
pubmed: 20099472
Moskala M, Goscinski I, Kaluza J, Polak J, Krupa M, Adamek D et al (2007) Morphological aspects of the traumatic chronic subdural hematoma capsule: SEM studies. Microsc Microanal 13(3):211–219
doi: 10.1017/S1431927607070286
pubmed: 17490504
Nanko N, Tanikawa M, Mase M, Fujita M, Tateyama H, Miyati T, Yamada K (2009) Involvement of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in the mechanism of development of chronic subdural hematoma. Neurol Med Chir (Tokyo) 49(9):379–385
doi: 10.2176/nmc.49.379
pubmed: 19779281
Sarkar C, Lakhtakia R, Gill SS, Sharma MC, Mahapatra AK, Mehta VS (2002) Chronic subdural haematoma and the enigmatic eosinophil. Acta Neurochir (Wien) 144(10):983–988 discussion 8
doi: 10.1007/s00701-002-0994-6
pubmed: 12382126
Shono T, Inamura T, Morioka T, Matsumoto K, Suzuki SO, Ikezaki K et al (2001) Vascular endothelial growth factor in chronic subdural haematomas. J Clin Neurosci 8(5):411–415
doi: 10.1054/jocn.2000.0951
pubmed: 11535006
Kristof RA, Grimm JM, Stoffel-Wagner B (2008) Cerebrospinal fluid leakage into the subdural space: possible influence on the pathogenesis and recurrence frequency of chronic subdural hematoma and subdural hygroma. J Neurosurg 108(2):275–280
doi: 10.3171/JNS/2008/108/2/0275
pubmed: 18240922
Murakami H, Hirose Y, Sagoh M, Shimizu K, Kojima M, Gotoh K et al (2002) Why do chronic subdural hematomas continue to grow slowly and not coagulate? Role of thrombomodulin in the mechanism. J Neurosurg 96(5):877–884
doi: 10.3171/jns.2002.96.5.0877
pubmed: 12005395
Kurihara A, Ohuchi K, Tsurufuji S (1984) Reduction by dexamethasone of chemotactic activity in inflammatory exudates. Eur J Pharmacol 101(1–2):11–16
doi: 10.1016/0014-2999(84)90025-6
pubmed: 6745316
Messer EJ, Keller JJ (1975) The use of intraoral dexamethasone after extraction of mandibular third molars. Oral Surg Oral Med Oral Pathol 40(5):594–598
doi: 10.1016/0030-4220(75)90369-2
pubmed: 1059060
Thotakura AK, Marabathina NR (2015) Nonsurgical treatment of chronic subdural hematoma with steroids. World Neurosurg 84(6):1968–1972
doi: 10.1016/j.wneu.2015.08.044
pubmed: 26342776
Zhang Y, Chen S, Xiao Y, Tang W (2017) Effects of Dexamethasone in the treatment of recurrent chronic subdural hematoma. World Neurosurg 105:115–121
doi: 10.1016/j.wneu.2017.05.135
pubmed: 28578110
Wang D, Gao C, Xu X, Chen T, Tian Y, Wei H et al (2020) Treatment of chronic subdural hematoma with atorvastatin combined with low-dose dexamethasone: phase II randomized proof-of-concept clinical trial. J Neurosurg 134(1):235–243
doi: 10.3171/2019.11.JNS192020
pubmed: 32005012
Jiang R, Zhao S, Wang R, Feng H, Zhang J, Li X et al (2018) Safety and efficacy of atorvastatin for chronic subdural hematoma in Chinese patients: a Randomized ClinicalTrial. JAMA Neurol 75(11):1338–1346
pmcid: 6248109
doi: 10.1001/jamaneurol.2018.2030
pubmed: 30073290
Dran G, Berthier F, Fontaine D, Rasenrarijao D, Paquis P (2007) [Effectiveness of adjuvant corticosteroid therapy for chronic subdural hematoma: a retrospective study of 198 cases]. Neurochirurgie 53(6):477–482
doi: 10.1016/j.neuchi.2007.09.146
pubmed: 18061628
Miah IP, Holl DC, Blaauw J, Lingsma HF, den Hertog HM, Jacobs B et al (2023) Dexamethasone versus surgery for chronic subdural hematoma. N Engl J Med 388(24):2230–2240
doi: 10.1056/NEJMoa2216767
pubmed: 37314705
Dexamethasone Therapy in Symptomatic Chronic Subdural Hematoma (DECSA–R) (2020) A retrospective evaluation of initial corticosteroid therapy versus primary surgery. J Neurotrauma 37(2):366–372
doi: 10.1089/neu.2019.6541
Hutchinson PJ, Edlmann E, Bulters D, Zolnourian A, Holton P, Suttner N et al (2020) Trial of Dexamethasone for Chronic Subdural Hematoma. N Engl J Med 383(27):2616–2627
doi: 10.1056/NEJMoa2020473
pubmed: 33326713
Jessurun CAC, Hulsbergen AFC, Lamba N, Nandoe Tewarie RDS, Smith TR, Broekman MLD (2022) Practice variation in Perioperative Steroid Dosing for Brain Tumor patients: an International Survey. World Neurosurg 159:e431–e41
doi: 10.1016/j.wneu.2021.12.067
pubmed: 34958992
Roquilly A, Vourc’h M, Cinotti R, Asehnoune K (2013) A new way of thinking: hydrocortisone in traumatic brain-injured patients. Crit Care 17(6):1016
pmcid: 4059383
doi: 10.1186/cc13138
pubmed: 24313953
Chen X, Zhao Z, Chai Y, Luo L, Jiang R, Dong J, Zhang J (2013) Stress-dose hydrocortisone reduces critical illness-related corticosteroid insufficiency associated with severe traumatic brain injury in rats. Crit Care 17(5):R241
pmcid: 4057521
doi: 10.1186/cc13067
pubmed: 24131855
Roquilly A, Mahe PJ, Seguin P, Guitton C, Floch H, Tellier AC et al (2011) Hydrocortisone therapy for patients with multiple trauma: the randomized controlled HYPOLYTE study. JAMA 305(12):1201–1209
doi: 10.1001/jama.2011.360
pubmed: 21427372
Annane D, Bellissant E, Bollaert PE, Briegel J, Confalonieri M, De Gaudio R et al (2009) Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review. JAMA 301(22):2362–2375
doi: 10.1001/jama.2009.815
pubmed: 19509383
Désir LL, D’Amico R, Link T, Silva D, Ellis JA, Doron O et al (2021) Middle meningeal artery embolization and the treatment of a chronic subdural hematoma. Cureus 13(10):e18868
pmcid: 8570051
pubmed: 34754700
Feghali J, Yang W, Huang J (2020) Updates in chronic subdural hematoma: epidemiology, etiology, Pathogenesis, treatment, and Outcome. World Neurosurg 141:339–345
doi: 10.1016/j.wneu.2020.06.140
pubmed: 32593768
Joyce E, Bounajem MT, Scoville J, Thomas AJ, Ogilvy CS, Riina HA et al (2020) Middle meningeal artery embolization treatment of nonacute subdural hematomas in the elderly: a multiinstitutional experience of 151 cases. Neurosurg Focus 49(4):E5
doi: 10.3171/2020.7.FOCUS20518
pubmed: 33002874
Di Cristofori A, Remida P, Patassini M, Piergallini L, Buonanno R, Bruno R et al (2022) Middle meningeal artery embolization for chronic subdural hematomas. A systematic review of the literature focused on indications, technical aspects, and future possible perspectives. Surg Neurol Int 13:94
pmcid: 8986643
doi: 10.25259/SNI_911_2021
pubmed: 35399896