NORTH AMERICAN EXPERT CONSENSUS ON THE POST-PROCEDURAL CARE OF PATIENTS AFTER PER-ORAL ENDOSCOPIC MYOTOMY USING A DELPHI PROCESS.

Delphi process POEM per-oral endoscopic myotomy

Journal

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
ISSN: 1542-7714
Titre abrégé: Clin Gastroenterol Hepatol
Pays: United States
ID NLM: 101160775

Informations de publication

Date de publication:
28 Aug 2024
Historique:
received: 26 04 2024
revised: 02 08 2024
accepted: 18 08 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 30 8 2024
Statut: aheadofprint

Résumé

There is significant variability in the immediate post-operative and long-term management of patients undergoing per-oral endoscopic myotomy (POEM), largely stemming from the lack of high-quality evidence. We aimed to establish a consensus on several important questions on the after care of post-POEM patients through a modified Delphi process. A steering committee developed an initial questionnaire consisting of 5 domains (33 statements): post-POEM admission/discharge, indication for immediate post-POEM esophagram, peri-procedural medications and diet resumption, clinic follow-up recommendations, and post-POEM reflux surveillance and management. A total of 34 experts participated in the 2 rounds of the Delphi process, with quantitative and qualitative data analyzed for each round to achieve consensus. A total of 23 statements achieved high degree of consensus. Overall, the expert panel agreed on the following: (1) same-day discharge after POEM can be considered in select patients, (2) a single dose of prophylactic antibiotics may be as effective as a short course, (3) a modified diet can be advanced as tolerated, (4) all patients should be followed in clinic and undergo objective testing for surveillance and management of reflux. Consensus could not be achieved on the indication of post-POEM esophagram to evaluate for leak. The results of this Delphi process established expert agreement on several important issues and provides a practical guidance on key aspects in the care of patients following POEM.

Sections du résumé

BACKGROUND AND AIMS OBJECTIVE
There is significant variability in the immediate post-operative and long-term management of patients undergoing per-oral endoscopic myotomy (POEM), largely stemming from the lack of high-quality evidence. We aimed to establish a consensus on several important questions on the after care of post-POEM patients through a modified Delphi process.
METHODS METHODS
A steering committee developed an initial questionnaire consisting of 5 domains (33 statements): post-POEM admission/discharge, indication for immediate post-POEM esophagram, peri-procedural medications and diet resumption, clinic follow-up recommendations, and post-POEM reflux surveillance and management. A total of 34 experts participated in the 2 rounds of the Delphi process, with quantitative and qualitative data analyzed for each round to achieve consensus.
RESULTS RESULTS
A total of 23 statements achieved high degree of consensus. Overall, the expert panel agreed on the following: (1) same-day discharge after POEM can be considered in select patients, (2) a single dose of prophylactic antibiotics may be as effective as a short course, (3) a modified diet can be advanced as tolerated, (4) all patients should be followed in clinic and undergo objective testing for surveillance and management of reflux. Consensus could not be achieved on the indication of post-POEM esophagram to evaluate for leak.
CONCLUSIONS CONCLUSIONS
The results of this Delphi process established expert agreement on several important issues and provides a practical guidance on key aspects in the care of patients following POEM.

Identifiants

pubmed: 39214390
pii: S1542-3565(24)00792-4
doi: 10.1016/j.cgh.2024.08.024
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Auteurs

Dennis Yang (D)

Center for Interventional Endoscopy, AdventHealth, Orlando, FL. Electronic address: dennis.yang.md@adventhealth.com.

Abdul Mohammed (A)

Gastroenterology, AdventHealth Medical Group, Orlando, FL.

Rena Yadlapati (R)

Division of Gastroenterology, University of California San Diego, San Diego, CA.

Andrew Y Wang (AY)

Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA.

Thurarshen Jeyalingam (T)

Division of Gastroenterology and Hepatology, University of Toronto, Ontario, Canada.

Peter V Draganov (PV)

Division of Gastroenterology and Hepatology, University of Florida, Gainesville, FL.

Ernesto Robalino Gonzaga (E)

Gastroenterology, AdventHealth Medical Group, Orlando, FL.

Muhammad K Hasan (MK)

Center for Interventional Endoscopy, AdventHealth, Orlando, FL.

Alexander Schlachterman (A)

Division of Gastroenterology, Thomas Jefferson University Hospital, Philadelphia, PA.

Ming-Ming Xu (MM)

Department of Gastroenterology, Kaiser Permanente West LA, Los Angeles, CA.

Ahmed Saeed (A)

Kansas City Gastroenterology and Hepatology Physicians Group, Kansas City, MO.

Aziz Aadam (A)

Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Reem Z Sharaiha (RZ)

Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, NY.

Ryan Law (R)

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

Louis M Wong Kee Song (LM)

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

Monica Saumoy (M)

Center for Digestive Health, Penn Medicine Princeton Health, Plainsboro, NJ.

John E Pandolfino (JE)

Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Makoto Nishimura (M)

Gastroenterology, Hepatology, and Nutrition Service, Memorial Sloan Kettering Cancer Center, New York, NY.

Michel Kahaleh (M)

Department of Gastroenterology, Robert Wood Johnson University Hospital, New Brunswick, NJ.

Joo Ha Hwang (JH)

Department of Gastroenterology, Stanford University School of Medicine, CA.

Robert Bechara (R)

Queen's University, Division of Gastroenterology, Kingston Health Science Center, Kingston, Ontario, Canada.

Vani Ja Konda (VJ)

Division of Gastroenterology, Baylor University Medical Center, Dallas, TX.

John M DeWitt (JM)

Department of Gastroenterology and Hepatology, Indiana University School of Medicine, IN.

Prashant Kedia (P)

Methodist Dallas Medical Center, Dallas, TX.

Nikhil A Kumta (NA)

Division of Gastroenterology, Mount Sinai Hospital, New York, New York.

Irteza Inayat (I)

Gastroenterology, AdventHealth Medical Group, Orlando, FL.

Stavros N Stavropoulos (SN)

Division of Gastroenterology, Mount Sinai-South Nassau Hospital, New York, NY.

Vivek Kumbhari (V)

Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Jacksonville, FL.

Uzma D Siddiqui (UD)

Center for Endoscopic Research and Therapeutics, University of Chicago, Chicago, IL.

Salmaan Jawaid (S)

Division of Gastroenterology, Baylor University Medical Center, Dallas, TX.

Sherif Andrawes (S)

Division of Gastroenterology and Hepatology, Department of Medicine, Staten Island University Hospital - Northwell Health, Staten Island, NY.

Mouen Khashab (M)

Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, MD.

Joseph R Triggs (JR)

Division of Gastroenterology, Fox Chase Cancer Center, Temple Health, PA.

Neil Sharma (N)

Division of Interventional Oncology and Surgical Endoscopy (IOSE), Parkview Cancer Institute, IN.

Mohamed Othman (M)

Division of Gastroenterology, Baylor University Medical Center, Dallas, TX.

Amrita Sethi (A)

Division of Digestive and Liver Disease, Columbia University Irving Medical Center, New York, NY.

Alexandra J Baumann (AJ)

Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Cyrus Priraka (C)

Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.

Christy M Dunst (CM)

Division of Gastrointestinal and Minimally Invasive Surgery, The Oregon Clinic Center for Advanced Surgery.

Mihir S Wagh (MS)

Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Jacksonville, FL.

Mohammad Al-Haddad (M)

Department of Gastroenterology and Hepatology, Indiana University School of Medicine, IN.

C Prakash Gayawali (CP)

Division of Gastroenterology, Washington University School of Medicine, St Louis, MO.

Sergey Kantsevoy (S)

Institute for Digestive Health and Liver Diseases, Mercy Medical Center, Baltimore, MD.

B Joseph Elmunzer (BJ)

Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, SC.

Classifications MeSH