Beyond the incubator: applying a "one health" approach in the NICU.


Journal

Pediatric research
ISSN: 1530-0447
Titre abrégé: Pediatr Res
Pays: United States
ID NLM: 0100714

Informations de publication

Date de publication:
30 Aug 2024
Historique:
received: 31 01 2024
accepted: 21 08 2024
revised: 07 08 2024
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 30 8 2024
Statut: aheadofprint

Résumé

A "one health" approach recognises that human health, animal health and planetary health are closely interlinked and that a transdisciplinary approach is required to fully understand and maintain global health. While, by necessity, Neonatal Intensive Care has traditionally focused on the acutely unwell newborn, the avoidance of long-term harm is core to many management decisions. The COVID 19 pandemic and climate crisis have brought into sharp relief the importance of a "one health" approach as part of long-term health promotion in the holistic care of neonates, who may survive to experience the burden of future environmental crises. This narrative review seeks to integrate what we know about "one health" issues in the neonatal intensive care unit, notably antimicrobial resistance and climate change, and suggest "everyday changes" which can be utilised by practitioners to minimise the impact of neonatal intensive care on these global health issues. Many of the changes suggested not only represent important improvements for planetary health but are also core to good neonatal practice. IMPACT: Neonatal patients are likely to bear the burden of future environmental crises including pandemics and climate related disasters. While the focus of intensive care practitioners is acute illness, awareness of "one health" problems are important for our smallest patients as part of preventing long-term harm. High quality neonatal care can benefit both the planet and our patients.

Identifiants

pubmed: 39215199
doi: 10.1038/s41390-024-03534-4
pii: 10.1038/s41390-024-03534-4
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

Références

Organisation, W. H. One Health, https://www.who.int/news-room/questions-and-answers/item/one-health (2017).
control, C. F. D. About One Health, https://www.cdc.gov/one-health/about/index.html#:~:text=One%20Health%20is%20a%20collaborative,plants%2C%20and%20their%20shared%20environment . (2024).
Eurostat. Eu Life Expectancy at Birth 80.6 in 2022, https://ec.europa.eu/eurostat/web/products-eurostat-news/w/ddn-20240314-1#:~:text=In%202022%2C%20the%20life%20expectancy,3.7%20years%20compared%20with%202002) . (2024).
Boverman, G. et al. Neonatal Icu Antibiotic Use Trends within an Integrated Delivery Network. Antimicrob. Resist Infect. Control 11, 21 (2022).
pubmed: 35101129 pmcid: 8805293 doi: 10.1186/s13756-022-01057-3
Ramirez, C. B. & Cantey, J. B. Antibiotic Resistance in the Neonatal Intensive Care Unit. NeoReviews 20, e135–e144 (2019).
pubmed: 31261051 doi: 10.1542/neo.20-3-e135
Watts, N. et al. The 2019 Report of the Lancet Countdown on Health and Climate Change: Ensuring That the Health of a Child Born Today Is Not Defined by a Changing Climate. Lancet 394, 1836–1878 (2019).
pubmed: 31733928 doi: 10.1016/S0140-6736(19)32596-6
Prusakov, P. et al. A Global Point Prevalence Survey of Antimicrobial Use in Neonatal Intensive Care Units: The No-More-Antibiotics and Resistance (No-Mas-R) Study. eClinicalMedicine 32, 1–12 (2021).
Zven, S. E., Susi, A., Mitre, E. & Nylund, C. M. Association between Use of Multiple Classes of Antibiotic in Infancy and Allergic Disease in Childhood. JAMA Pediatrics 174, 199–200 (2020).
pubmed: 31860016 doi: 10.1001/jamapediatrics.2019.4794
Borbet, T. C. et al. Influence of the Early-Life Gut Microbiota on the Immune Responses to an Inhaled Allergen. Mucosal Immunol. 15, 1000–1011 (2022).
pubmed: 35842561 pmcid: 9835105 doi: 10.1038/s41385-022-00544-5
Wilkinson, A. & Woodcock, A. The Environmental Impact of Inhalers for Asthma: A Green Challenge and a Golden Opportunity. Br. J. Clin. Pharm. 88, 3016–3022 (2022).
doi: 10.1111/bcp.15135
Mccarthy, K. & Dempsey, E. Antimicrobial Stewardship in the Neonatal Unit: A quality Improvement Initiative. Open Forum Infect. Dis. 4, S267–S267 (2017).
pmcid: 5632147 doi: 10.1093/ofid/ofx163.590
Gyllensvärd, J. et al. Antibiotic Use in Late Preterm and Full-Term Newborns. JAMA Netw. Open 7, e243362–e243362 (2024).
pubmed: 38517437 pmcid: 10960197 doi: 10.1001/jamanetworkopen.2024.3362
Puopolo, K. M. et al. Management of Neonates Born at ≥35 0/7 Weeks’ Gestation with Suspected or Proven Early-Onset Bacterial Sepsis. Pediatrics 142, 1–10 (2018).
Giannoni, E. et al. Analysis of Antibiotic Exposure and Early-Onset Neonatal Sepsis in Europe, North America, and Australia. JAMA Netw. Open 5, e2243691 (2022).
pubmed: 36416819 pmcid: 9685486 doi: 10.1001/jamanetworkopen.2022.43691
Achten, N. B. et al. Association of Use of the Neonatal Early-Onset Sepsis Calculator with Reduction in Antibiotic Therapy and Safety: A Systematic Review and Meta-Analysis. JAMA Pediatr. 173, 1032–1040 (2019).
pubmed: 31479103 pmcid: 6724419 doi: 10.1001/jamapediatrics.2019.2825
Vatne, A. et al. Reduced Antibiotic Exposure by Serial Physical Examinations in Term Neonates at Risk of Early-Onset Sepsis. Pediatr. Infect. Dis. J. 39, 438–443 (2020).
de Man, P., Verhoeven, B. A. N., Verbrugh, H. A., Vos, M. C. & van den Anker, J. N. An Antibiotic Policy to Prevent Emergence of Resistant Bacilli. Lancet 355, 973–978 (2000).
pubmed: 10768436 doi: 10.1016/S0140-6736(00)90015-1
Ganatra, H. A., Stoll, B. J. & Zaidi, A. K. M. International Perspective on Early-Onset Neonatal Sepsis. Clin. Perinatol. 37, 501–523 (2010).
pubmed: 20569819 doi: 10.1016/j.clp.2010.02.004
Hamer, D. H. et al. Etiology of Bacteremia in Young Infants in Six Countries. Pediatr. Infect. Dis. J. 34, e1–e8 (2015).
pubmed: 25389919 doi: 10.1097/INF.0000000000000549
Investigators of the Delhi Neonatal Infection Study (DeNIS) collaboration. Characterisation and Antimicrobial Resistance of Sepsis Pathogens in Neonates Born in Tertiary Care Centres in Delhi, India: A Cohort Study. Lancet Glob. Health 4, e752-e760 (2016).
Keij, F. M. et al. Efficacy and Safety of Switching from Intravenous to Oral Antibiotics (Amoxicillin–Clavulanic Acid) Versus a Full Course of Intravenous Antibiotics in Neonates with Probable Bacterial Infection (Rain): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial. Lancet Child Adolesc. Health 6, 799–809 (2022).
pubmed: 36088952 doi: 10.1016/S2352-4642(22)00245-0
Morowitz, M. J. et al. The Nicu Antibiotics and Outcomes (Nano) Trial: A Randomized Multicenter Clinical Trial Assessing Empiric Antibiotics and Clinical Outcomes in Newborn Preterm Infants. Trials 23, 428 (2022).
pubmed: 35606829 pmcid: 9125935 doi: 10.1186/s13063-022-06352-3
Woodford, E. C. et al. Neonatal Blood Culture Inoculant Volume: Feasibility and Challenges. Pediatr. Res 90, 1086–1092 (2021).
pubmed: 33824451 pmcid: 8492767 doi: 10.1038/s41390-021-01484-9
Caggiano, G. et al. Candidemia in the Neonatal Intensive Care Unit: A Retrospective, Observational Survey and Analysis of Literature Data. Biomed. Res Int 2017, 7901763 (2017).
pubmed: 28884129 pmcid: 5572580 doi: 10.1155/2017/7901763
Al-Yasiri, M. H. et al. Opportunistic Fungal Pathogen Candida Glabrata Circulates between Humans and Yellow-Legged Gulls. Sci. Rep. 6, 36157 (2016).
pubmed: 27782182 pmcid: 5080578 doi: 10.1038/srep36157
Sharma, M. & Chakrabarti, A. On the Origin of Candida Auris: Ancestor, Environmental Stresses, and Antiseptics. mBio 11, https://doi.org/10.1128/mbio.02102-02120 (2020).
Chandramati, J., Sadanandan, L., Kumar, A. & Ponthenkandath, S. Neonatal Candida Auris Infection: Management and Prevention Strategies - a Single Centre Experience. J. Paediatr. Child Health 56, 1565–1569 (2020).
pubmed: 32672390 doi: 10.1111/jpc.15019
Ma, F., Xu, S., Tang, Z., Li, Z. & Zhang, L. Use of Antimicrobials in Food Animals and Impact of Transmission of Antimicrobial Resistance on Humans. Biosaf. Health 3, 32–38 (2021).
doi: 10.1016/j.bsheal.2020.09.004
Cobo-Angel, C. G. et al. Potential Group B Streptococcus Interspecies Transmission between Cattle and People in Colombian Dairy Farms. Sci. Rep. 9, 14025 (2019).
pubmed: 31575879 pmcid: 6773701 doi: 10.1038/s41598-019-50225-w
Sirimanapong, W., Phước, N. N., Crestani, C., Chen, S. & Zadoks, R. N. Geographical, Temporal and Host-Species Distribution of Potentially Human-Pathogenic Group B Streptococcus in Aquaculture Species in Southeast Asia. Pathogens 12, 1–11 (2023).
McGain, F., Story, D. & Hendel, S. An Audit of Intensive Care Unit Recyclable Waste. Anaesthesia 64, 1299–1302 (2009).
pubmed: 19804429 doi: 10.1111/j.1365-2044.2009.06102.x
Gaetani, M., Uleryk, E., Halgren, C. & Maratta, C. The Carbon Footprint of Critical Care: A Systematic Review. Intensive Care Med 50, 731–745 (2024).
pubmed: 38416200 doi: 10.1007/s00134-023-07307-1
Emont, J., Wang, M. & Wright, K. Health System Decarbonization on Obstetric and Newborn Units. Semin Perinatol. 47, 151844 (2023).
pubmed: 37852893 doi: 10.1016/j.semperi.2023.151844
Nichols, A. Sustainable Family Centred Care in the Neonatal Unit. J. Neonatal Nurs. 19, 266–270 (2013).
doi: 10.1016/j.jnn.2012.11.005
Shepley, M. M., Song, Y. & Marshall-Baker, A. Creating an Environmentally Sustainable Neonatal Intensive Care Unit. Newborn Infant Nurs. Rev. 16, 213–217 (2016).
doi: 10.1053/j.nainr.2016.09.027
Nichols, A., Grose, J. & Mukonoweshuro, R. Achieving Cost and Carbon Savings in Neonatal Practice: A Review of the Literature on Sustainable Waste Management. J. Neonatal Nurs. 22, 81–87 (2016).
doi: 10.1016/j.jnn.2016.01.002
Rizan, C., Bhutta, M. F., Reed, M. & Lillywhite, R. The Carbon Footprint of Waste Streams in a Uk Hospital. J. Clean. Prod. 286, 125446 (2021).
doi: 10.1016/j.jclepro.2020.125446
McAlister, S., Barratt, A. L., Bell, K. J. & McGain, F. The Carbon Footprint of Pathology Testing. Med. J. Aust. 212, 377–382 (2020).
pubmed: 32304240 doi: 10.5694/mja2.50583
Malik, A. et al. Environmental Impacts of Australia’s Largest Health System. Resour., Conserv. Recycling 169, 105556 (2021).
doi: 10.1016/j.resconrec.2021.105556
Ravindrane, R. & Patel, J. The Environmental Impacts of Telemedicine in Place of Face-to-Face Patient Care: A Systematic Review. Future Health. J. 9, 28–33 (2022).
doi: 10.7861/fhj.2021-0148
Purohit, A., Smith, J. & Hibble, A. Does Telemedicine Reduce the Carbon Footprint of Healthcare? A Systematic Review. Future Health. J. 8, e85–e91 (2021).
doi: 10.7861/fhj.2020-0080
Robinson, C., Gund, A., Sjöqvist, B.-A. & Bry, K. Using Telemedicine in the Care of Newborn Infants after Discharge from a Neonatal Intensive Care Unit Reduced the Need of Hospital Visits. Acta Paediatrica 105, 902–909 (2016).
pubmed: 26999007 doi: 10.1111/apa.13407
DeMauro, S. B., Duncan, A. F. & Hurt, H. Telemedicine Use in Neonatal Follow-up Programs - What Can We Do and What We Can’t - Lessons Learned from Covid-19. Semin Perinatol. 45, 151430 (2021).
pubmed: 33892961 pmcid: 8022519 doi: 10.1016/j.semperi.2021.151430
Smith, J. P. A Commentary on the Carbon Footprint of Milk Formula: Harms to Planetary Health and Policy Implications. Int. Breastfeed. J. 14, 49 (2019).
pubmed: 31798668 pmcid: 6882342 doi: 10.1186/s13006-019-0243-8
Rylander, C., Øyvind Odland, J. & Manning Sandanger, T. Climate Change and the Potential Effects on Maternal and Pregnancy Outcomes: An Assessment of the Most Vulnerable – the Mother, Fetus, and Newborn Child. Glob. Health Action 6, 19538 (2013).
pubmed: 23481091 doi: 10.3402/gha.v6i0.19538
Chersich, M. F. et al. Associations between High Temperatures in Pregnancy and Risk of Preterm Birth, Low Birth Weight, and Stillbirths: Systematic Review and Meta-Analysis. BMJ 371, m3811 (2020).
pubmed: 33148618 pmcid: 7610201 doi: 10.1136/bmj.m3811
Edney, J. M., Kovats, S., Filippi, V. & Nakstad, B. A Systematic Review of Hot Weather Impacts on Infant Feeding Practices in Low-and Middle-Income Countries. Front Pediatr. 10, 930348 (2022).
pubmed: 36147803 pmcid: 9485728 doi: 10.3389/fped.2022.930348
Dadvand, P., Basagana, X., Figueras, F., Sunyer, J. & Nieuwenhuijsen, M. J. Climate and Group B Streptococci Colonisation During Pregnancy: Present Implications and Future Concerns. BJOG: Int. J. Obstet. Gynaecol. 118, 1396–1400 (2011).
doi: 10.1111/j.1471-0528.2011.03044.x
MacFadden, D. R., McGough, S. F., Fisman, D., Santillana, M. & Brownstein, J. S. Antibiotic Resistance Increases with Local Temperature. Nat. Clim. Change 8, 510–514 (2018).
doi: 10.1038/s41558-018-0161-6
Schantz-Dunn, J. & Nour, N. M. Malaria and Pregnancy: A Global Health Perspective. Rev. Obstet. Gynecol. 2, 186–192 (2009).
pubmed: 19826576 pmcid: 2760896
Ryan, S. J., Lippi, C. A. & Zermoglio, F. Shifting Transmission Risk for Malaria in Africa with Climate Change: A Framework for Planning and Intervention. Malar. J. 19, 170 (2020).
pubmed: 32357890 pmcid: 7193356 doi: 10.1186/s12936-020-03224-6
Prevention, C. F. D. C. a. Locally Acquired Malaria Cases Identified in the United States, https://emergency.cdc.gov/han/2023/han00494.asp (2023).
Samarasekera, U. Climate Change and Malaria: Predictions Becoming Reality. Lancet 402, 361–362 (2023).
pubmed: 37517424 doi: 10.1016/S0140-6736(23)01569-6
Charlier, C., Beaudoin, M.-C., Couderc, T., Lortholary, O. & Lecuit, M. Arboviruses and Pregnancy: Maternal, Fetal, and Neonatal Effects. Lancet Child Adolesc. Health 1, 134–146 (2017).
pubmed: 30169203 doi: 10.1016/S2352-4642(17)30021-4
Gopakumar, H. & Ramachandran, S. Congenital Chikungunya. J. Clin. Neonatol. 1, 155–156 (2012).
pubmed: 24027715 pmcid: 3762016 doi: 10.4103/2249-4847.101704
Gupta, S., Choudhury, V., Gupta, N. P., Gupta, V. & Pandita, A. Congenital Dengue in Neonate. Clin. Case Rep. 9, 704–706 (2021).
pubmed: 33598228 doi: 10.1002/ccr3.3627

Auteurs

Daniel O'Reilly (D)

Department of Neonatology, Rotunda Hospital, Dublin 1, Ireland. daniel.oreilly2@ucdconnect.ie.
School of Biomolecular and Biomedical Science, University College Dublin, Dublin 4, Ireland. daniel.oreilly2@ucdconnect.ie.

Alison Livada (A)

Medical Scientist Training Program, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.

Laurie Steiner (L)

Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

Richard J Drew (RJ)

Irish Meningitis and Sepsis Reference Laboratory, Children's Health Ireland at Temple Street, Dublin, Ireland.
Clinical Innovation Unit, Rotunda Hospital, Dublin 1, Ireland.
Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin, Ireland.

Naomi Mc Callion (N)

Department of Neonatology, Rotunda Hospital, Dublin 1, Ireland.
Department of Paediatrics, Royal College of Surgeons in Ireland, Dublin, Ireland.

Classifications MeSH