The minimal important difference of one-minute-sit-to-stand test in subjects with chronic pulmonary aspergillosis.


Journal

Lung India : official organ of Indian Chest Society
ISSN: 0970-2113
Titre abrégé: Lung India
Pays: India
ID NLM: 8405380

Informations de publication

Date de publication:
01 Sep 2024
Historique:
received: 08 04 2024
accepted: 24 05 2024
medline: 1 9 2024
pubmed: 1 9 2024
entrez: 31 8 2024
Statut: ppublish

Résumé

There is a need for simple functional test to assess treatment response in chronic pulmonary aspergillosis (CPA) in resource-constrained settings. The one-minute-sit-to-stand test (1-min-STS) is one such test. However, the minimal important difference (MID) for 1-min-STS in subjects with CPA remains unknown. Herein, we estimate the MID for 1-min-STS for CPA subjects. We retrospectively reviewed the clinical details of CPA subjects treated with oral azoles for 6 months. We included only subjects who completed the 1-min-STS test at baseline and 6 months. We used the change in VAS (visual analogue scale, for overall improvement) as an external anchor. We used the anchor and the distribution (standard deviation-based) methods to determine the MID estimates. We used the anchor-based method only if there was correlation of 0.3 with the 1-min-STS test. One hundred-eight subjects completed the 1-min-STS test at baseline and 6 months. We did not find significant correlation between the change in VAS for overall improvement (r2 = 0.024, P value = 0.809) and the 1-min-STS test. The MID for the 1-min-STS test was 2 repetitions (range, 1.5-2.8 repetitions). The MID for the 1-min-STS test in subjects with CPA was 2 repetitions. Future studies using a global rating of change scale as an anchor must confirm our findings.

Sections du résumé

BACKGROUND AND OBJECTIVE OBJECTIVE
There is a need for simple functional test to assess treatment response in chronic pulmonary aspergillosis (CPA) in resource-constrained settings. The one-minute-sit-to-stand test (1-min-STS) is one such test. However, the minimal important difference (MID) for 1-min-STS in subjects with CPA remains unknown. Herein, we estimate the MID for 1-min-STS for CPA subjects.
MATERIALS AND METHODS METHODS
We retrospectively reviewed the clinical details of CPA subjects treated with oral azoles for 6 months. We included only subjects who completed the 1-min-STS test at baseline and 6 months. We used the change in VAS (visual analogue scale, for overall improvement) as an external anchor. We used the anchor and the distribution (standard deviation-based) methods to determine the MID estimates. We used the anchor-based method only if there was correlation of 0.3 with the 1-min-STS test.
RESULTS RESULTS
One hundred-eight subjects completed the 1-min-STS test at baseline and 6 months. We did not find significant correlation between the change in VAS for overall improvement (r2 = 0.024, P value = 0.809) and the 1-min-STS test. The MID for the 1-min-STS test was 2 repetitions (range, 1.5-2.8 repetitions).
CONCLUSION CONCLUSIONS
The MID for the 1-min-STS test in subjects with CPA was 2 repetitions. Future studies using a global rating of change scale as an anchor must confirm our findings.

Identifiants

pubmed: 39215977
doi: 10.4103/lungindia.lungindia_168_24
pii: 01408641-202409000-00004
doi:

Types de publication

Journal Article

Langues

eng

Pagination

353-356

Informations de copyright

Copyright © 2024 Copyright: © 2024 Indian Chest Society.

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Auteurs

Inderpaul Singh Sehgal (IS)

Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Sahajal Dhooria (S)

Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Valliappan Muthu (V)

Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Kuruswamy Thurai Prasad (KT)

Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Kathirvel Soundappan (K)

Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Ashutosh Nath Aggarwal (AN)

Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Arunaloke Chakrabarti (A)

Director, Doodhadhari Burfani Hospital, Haridwar, Uttarakhand, India.

Shivaprakash Mandya Rudramurthy (SM)

Department of Medical Microbiology Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Ritesh Agarwal (R)

Department of Pulmonary Medicine Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Classifications MeSH