Lateral cephalometric parameters among Arab skeletal classes II and III patients and applying machine learning models.


Journal

Clinical oral investigations
ISSN: 1436-3771
Titre abrégé: Clin Oral Investig
Pays: Germany
ID NLM: 9707115

Informations de publication

Date de publication:
03 Sep 2024
Historique:
received: 27 03 2024
accepted: 20 08 2024
medline: 3 9 2024
pubmed: 3 9 2024
entrez: 2 9 2024
Statut: epublish

Résumé

The World Health Organization considers malocclusion one of the most essential oral health problems. This disease influences various aspects of patients' health and well-being. Therefore, making it easier and more accurate to understand and diagnose patients with skeletal malocclusions is necessary. The main aim of this research was the establishment of machine learning models to correctly classify individual Arab patients, being citizens of Israel, as skeletal class II or III. Secondary outcomes of the study included comparing cephalometric parameters between patients with skeletal class II and III and between age and gender-specific subgroups, an analysis of the correlation of various cephalometric variables, and principal component analysis in skeletal class diagnosis. This quantitative, observational study is based on data from the Orthodontic Center, Jatt, Israel. The experimental data consisted of the coded records of 502 Arab patients diagnosed as Class II or III according to the Calculated_ANB. This parameter was defined as the difference between the measured ANB angle and the individualized ANB of Panagiotidis and Witt. In this observational study, we focused on the primary aim, i.e., the establishment of machine learning models for the correct classification of skeletal class II and III in a group of Arab orthodontic patients. For this purpose, various ML models and input data was tested after identifying the most relevant parameters by conducting a principal component analysis. As secondary outcomes this study compared the cephalometric parameters and analyzed their correlations between skeletal class II and III as well as between gender and age specific subgroups. Comparison of the two groups demonstrated significant differences between skeletal class II and class III patients. This was shown for the parameters NL-NSL angle, PFH/AFH ratio, SNA angle, SNB angle, SN-Ba angle. SN-Pg angle, and ML-NSL angle in skeletal class III patients, and for S-N (mm) in skeletal class II patients. In skeletal class II and skeletal class III patients, the results showed that the Calculated_ANB correlated well with many other cephalometric parameters. With the help of the Principal Component Analysis (PCA), it was possible to explain about 71% of the variation between the first two PCs. Finally, applying the stepwise forward Machine Learning models, it could be demonstrated that the model works only with the parameters Wits appraisal and SNB angle was able to predict the allocation of patients to either skeletal class II or III with an accuracy of 0.95, compared to a value of 0.99 when all parameters were used ("general model"). There is a significant relationship between many cephalometric parameters within the different groups of gender and age. This study highlights the high accuracy and power of Wits appraisal and the SNB angle in evaluating the classification of orthodontic malocclusion.

Sections du résumé

BACKGROUND BACKGROUND
The World Health Organization considers malocclusion one of the most essential oral health problems. This disease influences various aspects of patients' health and well-being. Therefore, making it easier and more accurate to understand and diagnose patients with skeletal malocclusions is necessary.
OBJECTIVES OBJECTIVE
The main aim of this research was the establishment of machine learning models to correctly classify individual Arab patients, being citizens of Israel, as skeletal class II or III. Secondary outcomes of the study included comparing cephalometric parameters between patients with skeletal class II and III and between age and gender-specific subgroups, an analysis of the correlation of various cephalometric variables, and principal component analysis in skeletal class diagnosis.
METHODS METHODS
This quantitative, observational study is based on data from the Orthodontic Center, Jatt, Israel. The experimental data consisted of the coded records of 502 Arab patients diagnosed as Class II or III according to the Calculated_ANB. This parameter was defined as the difference between the measured ANB angle and the individualized ANB of Panagiotidis and Witt. In this observational study, we focused on the primary aim, i.e., the establishment of machine learning models for the correct classification of skeletal class II and III in a group of Arab orthodontic patients. For this purpose, various ML models and input data was tested after identifying the most relevant parameters by conducting a principal component analysis. As secondary outcomes this study compared the cephalometric parameters and analyzed their correlations between skeletal class II and III as well as between gender and age specific subgroups.
RESULTS RESULTS
Comparison of the two groups demonstrated significant differences between skeletal class II and class III patients. This was shown for the parameters NL-NSL angle, PFH/AFH ratio, SNA angle, SNB angle, SN-Ba angle. SN-Pg angle, and ML-NSL angle in skeletal class III patients, and for S-N (mm) in skeletal class II patients. In skeletal class II and skeletal class III patients, the results showed that the Calculated_ANB correlated well with many other cephalometric parameters. With the help of the Principal Component Analysis (PCA), it was possible to explain about 71% of the variation between the first two PCs. Finally, applying the stepwise forward Machine Learning models, it could be demonstrated that the model works only with the parameters Wits appraisal and SNB angle was able to predict the allocation of patients to either skeletal class II or III with an accuracy of 0.95, compared to a value of 0.99 when all parameters were used ("general model").
CONCLUSION CONCLUSIONS
There is a significant relationship between many cephalometric parameters within the different groups of gender and age. This study highlights the high accuracy and power of Wits appraisal and the SNB angle in evaluating the classification of orthodontic malocclusion.

Identifiants

pubmed: 39223280
doi: 10.1007/s00784-024-05900-2
pii: 10.1007/s00784-024-05900-2
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

511

Informations de copyright

© 2024. The Author(s).

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Auteurs

Kareem Midlej (K)

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, University of Tel-Aviv, Tel-Aviv, 6997801, Israel.

Nezar Watted (N)

Center for Dentistry Research and Aesthetics, Jatt, 4491800, Israel.
Gathering for Prosperity Initiative, Jatt, 4491800, Israel.
Department of Orthodontics, Faculty of Dentistry, Arab America University, Jenin, PNA, Palestine.

Obaida Awadi (O)

Center for Dentistry Research and Aesthetics, Jatt, 4491800, Israel.

Samir Masarwa (S)

Center for Dentistry Research and Aesthetics, Jatt, 4491800, Israel.

Iqbal M Lone (IM)

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, University of Tel-Aviv, Tel-Aviv, 6997801, Israel.

Osayd Zohud (O)

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, University of Tel-Aviv, Tel-Aviv, 6997801, Israel.

Eva Paddenberg (E)

Department of Orthodontics, University Hospital of Regensburg, University of Regensburg, 93047, Regensburg, Germany.

Sebastian Krohn (S)

Department of Orthodontics, University Hospital of Regensburg, University of Regensburg, 93047, Regensburg, Germany.

Erika Kuchler (E)

Department of Orthodontics, University of Bonn, D-53111, Bonn, Germany.

Peter Proff (P)

Department of Orthodontics, University Hospital of Regensburg, University of Regensburg, 93047, Regensburg, Germany.

Fuad A Iraqi (FA)

Department of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, University of Tel-Aviv, Tel-Aviv, 6997801, Israel. fuadi@tauex.tau.ac.il.
Gathering for Prosperity Initiative, Jatt, 4491800, Israel. fuadi@tauex.tau.ac.il.
Department of Orthodontics, University Hospital of Regensburg, University of Regensburg, 93047, Regensburg, Germany. fuadi@tauex.tau.ac.il.

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