Association between celiac disease and fibromyalgia and their severity: a cross-sectional study.


Journal

PeerJ
ISSN: 2167-8359
Titre abrégé: PeerJ
Pays: United States
ID NLM: 101603425

Informations de publication

Date de publication:
2024
Historique:
received: 22 03 2024
accepted: 30 07 2024
medline: 3 9 2024
pubmed: 3 9 2024
entrez: 3 9 2024
Statut: epublish

Résumé

Fibromyalgia (FMS) is a common musculoskeletal disorder with many causes. People with fibromyalgia often have the same symptoms as people with celiac disease (CD). Demonstration of the coordination and frequency of FMS and CD is important for effective treatment. This is a single center cross-sectional clinical study. The study included 60 patients who were diagnosed with CD by the Gastroenterology Clinic based on American College of Gastroenterology (ACG) criteria. Patients were also asked to complete the Widespread Pain Index (WPI), Symptom Severity Scale (SSS), and Fibromyalgia Impact Questionnaire (FIQ) to diagnose fibromyalgia and assess its severity. The results were used to analyze the frequency of concomitance and relationship between the two diseases. The relationship between the clinical types of CD and the presence of fibromyalgia was insignificant. Analysis of the relationship between the pathologic typing of biopsy and fibromyalgia frequency was insignificant. Those with antibodies more frequently met criteria for fibromyalgia ( Presence of clinical extraintestinal manifestations in patients with CD should lead clinicians to consider FMS as a possible diagnosis. This points to the importance for clinicians in all subspecialties to be aware of the various symptoms and diseases associated with FMS.

Sections du résumé

Background UNASSIGNED
Fibromyalgia (FMS) is a common musculoskeletal disorder with many causes. People with fibromyalgia often have the same symptoms as people with celiac disease (CD). Demonstration of the coordination and frequency of FMS and CD is important for effective treatment.
Methods UNASSIGNED
This is a single center cross-sectional clinical study. The study included 60 patients who were diagnosed with CD by the Gastroenterology Clinic based on American College of Gastroenterology (ACG) criteria. Patients were also asked to complete the Widespread Pain Index (WPI), Symptom Severity Scale (SSS), and Fibromyalgia Impact Questionnaire (FIQ) to diagnose fibromyalgia and assess its severity. The results were used to analyze the frequency of concomitance and relationship between the two diseases.
Results UNASSIGNED
The relationship between the clinical types of CD and the presence of fibromyalgia was insignificant. Analysis of the relationship between the pathologic typing of biopsy and fibromyalgia frequency was insignificant. Those with antibodies more frequently met criteria for fibromyalgia (
Conclusions UNASSIGNED
Presence of clinical extraintestinal manifestations in patients with CD should lead clinicians to consider FMS as a possible diagnosis. This points to the importance for clinicians in all subspecialties to be aware of the various symptoms and diseases associated with FMS.

Identifiants

pubmed: 39224825
doi: 10.7717/peerj.17949
pii: 17949
pmc: PMC11368088
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e17949

Informations de copyright

© 2024 Kılıçoğlu et al.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

Auteurs

Mehmet Serkan Kılıçoğlu (MS)

Department of Physical Medicine and Rehabilitation, Bezmialem Vakif University, Istanbul, Fatih, Turkey.

Safiye Sayılır (S)

Department of Physical Medicine and Rehabilitation, Bezmialem Vakif University, Istanbul, Fatih, Turkey.

Ozan Volkan Yurdakul (OV)

Department of Physical Medicine and Rehabilitation, Bezmialem Vakif University, Istanbul, Fatih, Turkey.

Teoman Aydin (T)

Department of Physical Medicine and Rehabilitation, Bezmialem Vakif University, Istanbul, Fatih, Turkey.

Koray Koçhan (K)

Department of Gastroenterology, Bezmialem Vakif University, Istanbul, Fatih, Turkey.

Metin Basaranoglu (M)

Department of Gastroenterology, Bezmialem Vakif University, Istanbul, Fatih, Turkey.

Okan Kucukakkas (O)

Department of Physical Medicine and Rehabilitation, NMC Royal Hospital, Khalifa City, Abu Dhabi, United Arab Emirates.

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Classifications MeSH