Social relationship factors, depressive symptoms, and incident dementia: a prospective cohort study into their interrelatedness.

cohort study dementia depressive symptoms factor analysis prevention public health risk reduction social relationships structural equation modeling

Journal

Psychological medicine
ISSN: 1469-8978
Titre abrégé: Psychol Med
Pays: England
ID NLM: 1254142

Informations de publication

Date de publication:
04 Sep 2024
Historique:
medline: 4 9 2024
pubmed: 4 9 2024
entrez: 4 9 2024
Statut: aheadofprint

Résumé

Different aspects of social relationships (e.g., social network size or loneliness) have been associated with dementia risk, while their overlap and potentially underlying pathways remain largely unexplored. This study therefore aimed to (1) discriminate between different facets of social relationships by means of factor analysis, (2) examine their associations with dementia risk, and (3) assess mediation by depressive symptoms. Thirty-six items from questionnaires on social relationships administered in Wave 2 (2004/2005) of the English Longitudinal Study of Ageing ( Factor analyses identified six social factors. Across a median follow-up time of 11.8 years (IQR = 5.9-13.9 years), 501 people developed dementia. Higher factor scores for frequency and quality of contact with children (HR = 0.88; Frequency and quality of social contacts, social activity engagement, and feelings of loneliness are associated with dementia risk and might be suitable targets for dementia prevention programs, partly by lowering depressive symptoms.

Sections du résumé

BACKGROUND BACKGROUND
Different aspects of social relationships (e.g., social network size or loneliness) have been associated with dementia risk, while their overlap and potentially underlying pathways remain largely unexplored. This study therefore aimed to (1) discriminate between different facets of social relationships by means of factor analysis, (2) examine their associations with dementia risk, and (3) assess mediation by depressive symptoms.
METHODS METHODS
Thirty-six items from questionnaires on social relationships administered in Wave 2 (2004/2005) of the English Longitudinal Study of Ageing (
RESULTS RESULTS
Factor analyses identified six social factors. Across a median follow-up time of 11.8 years (IQR = 5.9-13.9 years), 501 people developed dementia. Higher factor scores for frequency and quality of contact with children (HR = 0.88;
CONCLUSIONS CONCLUSIONS
Frequency and quality of social contacts, social activity engagement, and feelings of loneliness are associated with dementia risk and might be suitable targets for dementia prevention programs, partly by lowering depressive symptoms.

Identifiants

pubmed: 39228209
doi: 10.1017/S0033291724001272
pii: S0033291724001272
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-11

Auteurs

Lukas A Duffner (LA)

Alzheimer Centrum Limburg, Mental Health and Neuroscience Research Institute (MHeNS), Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands.

Kay Deckers (K)

Alzheimer Centrum Limburg, Mental Health and Neuroscience Research Institute (MHeNS), Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands.

Dorina Cadar (D)

Department of Behavioural Science and Health, Institute of Epidemiology and Health, University College London, UK.
Department of Neuroscience, Centre for Dementia Studies, Brighton and Sussex Medical School, Brighton, UK.

Marjolein E de Vugt (ME)

Alzheimer Centrum Limburg, Mental Health and Neuroscience Research Institute (MHeNS), Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands.

Sebastian Köhler (S)

Alzheimer Centrum Limburg, Mental Health and Neuroscience Research Institute (MHeNS), Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, The Netherlands.

Classifications MeSH