NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansion.
Journal
bioRxiv : the preprint server for biology
ISSN: 2692-8205
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
21 Aug 2024
21 Aug 2024
Historique:
medline:
4
9
2024
pubmed:
4
9
2024
entrez:
4
9
2024
Statut:
epublish
Résumé
RNA repeat expansions fold into stable structures and cause microsatellite diseases such as Huntington's disease (HD), myotonic dystrophy type 1 (DM1), and spinocerebellar ataxias (SCAs). The trinucleotide expansion of r(CAG), or r(CAG)
Identifiants
pubmed: 39229124
doi: 10.1101/2024.08.20.608150
pmc: PMC11370455
pii:
doi:
Types de publication
Journal Article
Preprint
Langues
eng