Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.


Journal

PLOS global public health
ISSN: 2767-3375
Titre abrégé: PLOS Glob Public Health
Pays: United States
ID NLM: 9918283779606676

Informations de publication

Date de publication:
2024
Historique:
received: 18 04 2024
accepted: 12 08 2024
medline: 4 9 2024
pubmed: 4 9 2024
entrez: 4 9 2024
Statut: epublish

Résumé

Adherence to antiretroviral therapy (ART) among adolescents and young adults living with HIV (AYLHIV) in sub-Saharan Africa is sub-optimal compared to younger children and older adults. Adherence self-efficacy is one of the intrapersonal factors most strongly correlated with ART adherence. The role of adherence self-efficacy in ART adherence among AYLHIV is not well studied in Uganda. We enrolled 300 AYLHIV between October and December 2021 from an HIV clinic in southwestern Uganda. We collected information on adherence self-efficacy, HIV stigma, depression, self-management, and social skills. We used linear regression to estimate the association between adherence self-efficacy and the covariates of interest. At multivariable adjustment self-management (b = 0.29, 95% CI 0.23-0.35, p<0.001) and social skills (b = 0.16, 95% CI 0.08-0.24; p<0.001) were statistically significantly associated with adherence self-efficacy. The findings imply that interventions directed at enhancing self-management and social skills in AYLHIV may increase adherence self-efficacy and, potentially, HIV outcomes among AYLHIV.

Identifiants

pubmed: 39231105
doi: 10.1371/journal.pgph.0003600
pii: PGPH-D-24-00783
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e0003600

Informations de copyright

Copyright: © 2024 Ashaba et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

Dr. Tsai reports receiving a financial honorarium from Elsevier, Inc. for his work as Co-Editor in Chief of the Elsevier-owned journal SSM-Mental Health. The other authors have no conflict of Interest to declare.

Auteurs

Scholastic Ashaba (S)

Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda.

Charles Baguma (C)

Global Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.

Patricia Tushemereirwe (P)

Global Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.

Denis Nansera (D)

Department of Pediatrics, Mbarara University of Science and Technology, Mbarara, Uganda.

Samuel Maling (S)

Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda.

Brian C Zanon (BC)

Department of Pediatric Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America.
Department of Pediatric Infectious Diseases, Children's Healthcare of Atlanta, Goergia, United States of America.
Department of Pediatric Infectious, Emory University Rollins School of Public Health, Atlanta, Georgia, United States of America.

Alexander C Tsai (AC)

Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda.
Department of Psychiatry, Center for Global Health and Mongan Institute, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America.

Classifications MeSH