An aberrant immune-epithelial progenitor niche drives viral lung sequelae.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
04 Sep 2024
Historique:
received: 09 11 2023
accepted: 08 08 2024
medline: 5 9 2024
pubmed: 5 9 2024
entrez: 4 9 2024
Statut: aheadofprint

Résumé

The long-term physiological consequences of respiratory viral infections, particularly in the aftermath of the COVID-19 pandemic-termed post-acute sequelae of SARS-CoV-2 (PASC)-are rapidly evolving into a major public health concern

Identifiants

pubmed: 39232171
doi: 10.1038/s41586-024-07926-8
pii: 10.1038/s41586-024-07926-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Harish Narasimhan (H)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA, USA.

In Su Cheon (IS)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Wei Qian (W)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Sheng'en Shawn Hu (SS)

Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.

Tanyalak Parimon (T)

Women's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Chaofan Li (C)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Nick Goplen (N)

Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.

Yue Wu (Y)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Xiaoqin Wei (X)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Young Min Son (YM)

Department of Systems Biotechnology, Chung-Ang University, Anseong, Korea.

Elizabeth Fink (E)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Gislane de Almeida Santos (G)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Jinyi Tang (J)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Changfu Yao (C)

Women's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Lyndsey Muehling (L)

Division of Asthma, Allergy and Immunology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Glenda Canderan (G)

Division of Asthma, Allergy and Immunology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Alexandra Kadl (A)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Abigail Cannon (A)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Samuel Young (S)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA, USA.

Riley Hannan (R)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Grace Bingham (G)

Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.

Mohammed Arish (M)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Arka Sen Chaudhari (A)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Jun Sub Im (JS)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Cameron L R Mattingly (CLR)

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Emory Center of Excellence for Influenza Research and Response, Atlanta, GA, USA.

Patcharin Pramoonjago (P)

School of Medicine, University of Virginia, Charlottesville, VA, USA.

Alberto Marchesvsky (A)

Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Jeffrey Sturek (J)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Jacob E Kohlmeier (JE)

Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
Emory Center of Excellence for Influenza Research and Response, Atlanta, GA, USA.

Yun Michael Shim (YM)

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Judith Woodfolk (J)

Division of Asthma, Allergy and Immunology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.

Chongzhi Zang (C)

Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA. zang@virginia.edu.

Peter Chen (P)

Women's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Peter.Chen@cshs.org.
Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Peter.Chen@cshs.org.

Jie Sun (J)

Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA, USA. js6re@virginia.edu.
Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, VA, USA. js6re@virginia.edu.
Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA, USA. js6re@virginia.edu.

Classifications MeSH