Patient-specific guides for consistently achieving R0 bone margins after resection of primary malignant bone tumors of the pelvis.
Humans
Female
Male
Retrospective Studies
Middle Aged
Margins of Excision
Bone Neoplasms
/ surgery
Adult
Neoplasm Recurrence, Local
/ surgery
Aged
Follow-Up Studies
Prognosis
Pelvic Bones
/ surgery
Young Adult
Osteotomy
/ methods
Surgery, Computer-Assisted
/ methods
Pelvic Neoplasms
/ surgery
Adolescent
3D printing
Patient-specific instrument
Pelvis
Primary malignant bone tumor
Journal
World journal of surgical oncology
ISSN: 1477-7819
Titre abrégé: World J Surg Oncol
Pays: England
ID NLM: 101170544
Informations de publication
Date de publication:
04 Sep 2024
04 Sep 2024
Historique:
received:
10
04
2024
accepted:
17
07
2024
medline:
5
9
2024
pubmed:
5
9
2024
entrez:
4
9
2024
Statut:
epublish
Résumé
Primary malignant bone tumor of the pelvis is an uncommon lesion, the resection of which via freehand osteotomy is subject to inaccuracy due to its three-dimensional anatomy. Patient-Specific Guides (PSG), also called Patient-Specific Instruments (PSI) are essential to ensure surgical planning and resection adequacy. Our aim was to assess their use and effectiveness. A monocentric retrospective study was conducted on 42 adult patients who underwent PSG-based resection of a primary malignant bone tumor of the pelvis. The primary outcome was the proportion of R0 bone margins. The secondary outcomes were the proportion of overall R0 margins, considering soft-tissue resection, the cumulative incidence of local recurrence, and the time of production for the guides. A comparison to a previous series at our institution was performed regarding histological margins. Using PSGs, 100% R0 safe bone margin was achieved, and 88% overall R0 margin due to soft-tissue resection being contaminated, while the comparison to the previous series showed only 80% of R0 safe bone margin. The cumulative incidences of local recurrence were 10% (95% CI: 4-20%) at one year, 15% (95% CI: 6-27%) at two years, and 19% (95% CI: 8-33%) at five years. The median overall duration of the fabrication process of the guide was 35 days (Q1-Q3: 26-47) from the first contact to the surgery date. Patient-Specific Guides can provide a reproducible safe bony margin.
Identifiants
pubmed: 39232698
doi: 10.1186/s12957-024-03478-3
pii: 10.1186/s12957-024-03478-3
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
233Informations de copyright
© 2024. The Author(s).
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