Case Report: Glans penile necrosis in a patient with SARS-CoV-2 and leprosy infection.


Journal

F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320

Informations de publication

Date de publication:
2022
Historique:
accepted: 01 02 2024
pubmed: 21 4 2022
medline: 21 4 2022
entrez: 5 9 2024
Statut: epublish

Résumé

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was firstly identified in China and has been declared a global pandemic. Several serious extrapulmonary manifestations due to SARS-CoV-2 infection have also been reported and associated with hypercoagulability thrombotic vasculopathy. In addition, cases of Here, we report a 56-year-old male with coronavirus disease-19 (COVID-19) with concomitant leprosy infection with manifestation of glans penile necrosis, presented to the emergency department with acute penile pain. This case is unique because no occlusion blood flow to the penile was observed in the radiographic imaging. We described the potential pathophysiology in this case through a literature review. The patient received treatment according to the COVID-19 protocol and was given low molecular weight heparin (LMWH) therapy for 4 days. During the follow up, the clinical and functional condition of the penis showed significant improvement. Microthrombus involvement, platelet abnormalities and impaired hemostasis due to SARS-CoV-2 and leprosy co-infection are the hypothesis in this case report.

Sections du résumé

Background UNASSIGNED
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was firstly identified in China and has been declared a global pandemic. Several serious extrapulmonary manifestations due to SARS-CoV-2 infection have also been reported and associated with hypercoagulability thrombotic vasculopathy. In addition, cases of
Methods UNASSIGNED
Here, we report a 56-year-old male with coronavirus disease-19 (COVID-19) with concomitant leprosy infection with manifestation of glans penile necrosis, presented to the emergency department with acute penile pain. This case is unique because no occlusion blood flow to the penile was observed in the radiographic imaging. We described the potential pathophysiology in this case through a literature review.
Results UNASSIGNED
The patient received treatment according to the COVID-19 protocol and was given low molecular weight heparin (LMWH) therapy for 4 days. During the follow up, the clinical and functional condition of the penis showed significant improvement.
Conclusions UNASSIGNED
Microthrombus involvement, platelet abnormalities and impaired hemostasis due to SARS-CoV-2 and leprosy co-infection are the hypothesis in this case report.

Identifiants

pubmed: 39233873
doi: 10.12688/f1000research.84355.3
pmc: PMC11372346
doi:

Substances chimiques

Heparin, Low-Molecular-Weight 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

142

Informations de copyright

Copyright: © 2024 Ismy J et al.

Déclaration de conflit d'intérêts

No competing interests were disclosed.

Auteurs

Jufriady Ismy (J)

Division of Urology, Department of Surgery, Dr. Zainoel Abidin General Hospital, Universitas Syiah Kuala, Banda Aceh, Aceh, 23230, Indonesia.

Said Alfin Khalilullah (SA)

Division of Urology, Department of Surgery, Dr. Zainoel Abidin General Hospital, Universitas Syiah Kuala, Banda Aceh, Aceh, 23230, Indonesia.

Aditya Fajar Bahagianto (AF)

Division of Urology, Department of Surgery, Dr. Hasan Sadikin General Hospital, Universitas Padjajaran, Bandung, Indonesia.

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Classifications MeSH