Increasing situational awareness through nowcasting of the reproduction number.


Journal

Frontiers in public health
ISSN: 2296-2565
Titre abrégé: Front Public Health
Pays: Switzerland
ID NLM: 101616579

Informations de publication

Date de publication:
2024
Historique:
received: 10 05 2024
accepted: 05 08 2024
medline: 5 9 2024
pubmed: 5 9 2024
entrez: 5 9 2024
Statut: epublish

Résumé

The time-varying reproduction number R is a critical variable for situational awareness during infectious disease outbreaks; however, delays between infection and reporting of cases hinder its accurate estimation in real-time. A number of nowcasting methods, leveraging available information on data consolidation delays, have been proposed to mitigate this problem. In this work, we retrospectively validate the use of a nowcasting algorithm during 18 months of the COVID-19 pandemic in Italy by quantitatively assessing its performance against standard methods for the estimation of R. Nowcasting significantly reduced the median lag in the estimation of R from 13 to 8 days, while concurrently enhancing accuracy. Furthermore, it allowed the detection of periods of epidemic growth with a lead of between 6 and 23 days. Nowcasting augments epidemic awareness, empowering better informed public health responses.

Sections du résumé

Background UNASSIGNED
The time-varying reproduction number R is a critical variable for situational awareness during infectious disease outbreaks; however, delays between infection and reporting of cases hinder its accurate estimation in real-time. A number of nowcasting methods, leveraging available information on data consolidation delays, have been proposed to mitigate this problem.
Methods UNASSIGNED
In this work, we retrospectively validate the use of a nowcasting algorithm during 18 months of the COVID-19 pandemic in Italy by quantitatively assessing its performance against standard methods for the estimation of R.
Results UNASSIGNED
Nowcasting significantly reduced the median lag in the estimation of R from 13 to 8 days, while concurrently enhancing accuracy. Furthermore, it allowed the detection of periods of epidemic growth with a lead of between 6 and 23 days.
Conclusions UNASSIGNED
Nowcasting augments epidemic awareness, empowering better informed public health responses.

Identifiants

pubmed: 39234082
doi: 10.3389/fpubh.2024.1430920
pmc: PMC11371679
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1430920

Informations de copyright

Copyright © 2024 Bizzotto, Guzzetta, Marziano, Del Manso, Mateo Urdiales, Petrone, Cannone, Sacco, Poletti, Manica, Zardini, Trentini, Fabiani, Bella, Riccardo, Pezzotti, Ajelli and Merler.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Auteurs

Andrea Bizzotto (A)

Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Department of Mathematics, University of Trento, Trento, Italy.

Giorgio Guzzetta (G)

Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.

Valentina Marziano (V)

Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.

Martina Del Manso (M)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Alberto Mateo Urdiales (A)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Daniele Petrone (D)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Andrea Cannone (A)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Chiara Sacco (C)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Piero Poletti (P)

Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.

Mattia Manica (M)

Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.

Agnese Zardini (A)

Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.

Filippo Trentini (F)

Covid Crisis Lab, Bocconi University, Milan, Italy.
Department of Social and Political Sciences, Bocconi University, Milan, Italy.

Massimo Fabiani (M)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Antonino Bella (A)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Flavia Riccardo (F)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Patrizio Pezzotti (P)

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Marco Ajelli (M)

Laboratory for Computational Epidemiology and Public Health, Department of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN, United States.

Stefano Merler (S)

Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.

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