Worldwide organization and structures for kidney transplantation services.


Journal

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
ISSN: 1460-2385
Titre abrégé: Nephrol Dial Transplant
Pays: England
ID NLM: 8706402

Informations de publication

Date de publication:
05 Sep 2024
Historique:
received: 27 02 2024
medline: 5 9 2024
pubmed: 5 9 2024
entrez: 5 9 2024
Statut: ppublish

Résumé

Kidney transplantation (KT) is the preferred modality of kidney replacement therapy with better patient outcomes and quality of life compared with dialytic therapies. This study aims to evaluate the epidemiology, accessibility and availability of KT services in countries and regions around the world. This study relied on data from an international survey of relevant stakeholders (clinicians, policymakers and patient advocates) from countries affiliated with the International Society of Nephrology that was conducted from July to September 2022. Survey questions related to the availability, access, donor type and cost of KT. In total, 167 countries responded to the survey. KT services were available in 70% of all countries, including 86% of high-income countries, but only 21% of low-income countries. In 80% of countries, access to KT was greater in adults than in children. The median global prevalence of KT was 279.0 [interquartile range (IQR) 58.0-492.0] per million people (pmp) and the median global incidence was 12.2 (IQR 3.0-27.8) pmp. Pre-emptive KT remained exclusive to high- and upper-middle-income countries, and living donor KT was the only available modality for KT in low-income countries. The median cost of the first year of KT was $26 903 USD and varied 1000-fold between the most and least expensive countries. The availability, access and affordability of KT services, especially in low-income countries, remain limited. There is an exigent need to identify strategies to ensure equitable access to KT services for people with kidney failure worldwide, especially in the low-income countries.

Sections du résumé

BACKGROUND BACKGROUND
Kidney transplantation (KT) is the preferred modality of kidney replacement therapy with better patient outcomes and quality of life compared with dialytic therapies. This study aims to evaluate the epidemiology, accessibility and availability of KT services in countries and regions around the world.
METHODS METHODS
This study relied on data from an international survey of relevant stakeholders (clinicians, policymakers and patient advocates) from countries affiliated with the International Society of Nephrology that was conducted from July to September 2022. Survey questions related to the availability, access, donor type and cost of KT.
RESULTS RESULTS
In total, 167 countries responded to the survey. KT services were available in 70% of all countries, including 86% of high-income countries, but only 21% of low-income countries. In 80% of countries, access to KT was greater in adults than in children. The median global prevalence of KT was 279.0 [interquartile range (IQR) 58.0-492.0] per million people (pmp) and the median global incidence was 12.2 (IQR 3.0-27.8) pmp. Pre-emptive KT remained exclusive to high- and upper-middle-income countries, and living donor KT was the only available modality for KT in low-income countries. The median cost of the first year of KT was $26 903 USD and varied 1000-fold between the most and least expensive countries.
CONCLUSION CONCLUSIONS
The availability, access and affordability of KT services, especially in low-income countries, remain limited. There is an exigent need to identify strategies to ensure equitable access to KT services for people with kidney failure worldwide, especially in the low-income countries.

Identifiants

pubmed: 39235196
pii: 7749759
doi: 10.1093/ndt/gfae144
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

ii26-ii34

Subventions

Organisme : International Society of Nephrology
Organisme : University of Alberta
ID : RES0033080

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of the ERA.

Auteurs

Andrea K Viecelli (AK)

Department of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

Ryan Gately (R)

Department of Kidney and Transplant Services, Division of Medicine, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.

Zunaid Barday (Z)

Nephrology and Hypertension Division, Department of Medicine, University of Cape Town, Cape Town, South Africa.

Soroush Shojai (S)

Division of Nephrology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Silvia Arruebo (S)

The International Society of Nephrology, Brussels, Belgium.

Fergus J Caskey (FJ)

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Sandrine Damster (S)

The International Society of Nephrology, Brussels, Belgium.

Jo-Ann Donner (JA)

The International Society of Nephrology, Brussels, Belgium.

Vivekanand Jha (V)

George Institute for Global Health, University of New South Wales (UNSW), New Delhi, India.

Adeera Levin (A)

Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

Masaomi Nangaku (M)

Division of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Syed Saad (S)

Division of Nephrology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Marcello Tonelli (M)

Department of Medicine, University of Calgary, Calgary, Alberta, Canada.

Feng Ye (F)

Division of Nephrology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Ikechi G Okpechi (IG)

Division of Nephrology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

Aminu K Bello (AK)

Division of Nephrology and Immunology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

David W Johnson (DW)

Centre for Kidney Disease Research, University of Queensland at Princess Alexandra Hospital, Brisbane, Queensland, Australia.

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