Myo-regressor Deep Informed Neural NetwOrk (Myo-DINO) for fast MR parameters mapping in neuromuscular disorders.

Deep Learning Extended Phase Graph MR parameter mapping Neuromuscular Disorders Physics-Informed Neural Network

Journal

Computer methods and programs in biomedicine
ISSN: 1872-7565
Titre abrégé: Comput Methods Programs Biomed
Pays: Ireland
ID NLM: 8506513

Informations de publication

Date de publication:
28 Aug 2024
Historique:
received: 06 06 2024
revised: 25 08 2024
accepted: 26 08 2024
medline: 6 9 2024
pubmed: 6 9 2024
entrez: 5 9 2024
Statut: aheadofprint

Résumé

Magnetic Resonance (MR) parameters mapping in muscle Magnetic Resonance Imaging (mMRI) is predominantly performed using pattern recognition-based algorithms, which are characterised by high computational costs and scalability issues in the context of multi-parametric mapping. Deep Learning (DL) has been demonstrated to be a robust and efficient method for rapid MR parameters mapping. However, its application in mMRI domain to investigate Neuromuscular Disorders (NMDs) has not yet been explored. In addition, data-driven DL models suffered in interpretation and explainability of the learning process. We developed a Physics Informed Neural Network called Myo-Regressor Deep Informed Neural NetwOrk (Myo-DINO) for efficient and explainable Fat Fraction (FF), water-T

Identifiants

DOI: 10.1016/j.cmpb.2024.108399 PMID: 39236561
pubmed: 39236561
pii: S0169-2607(24)00392-4
doi: 10.1016/j.cmpb.2024.108399
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108399

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest LB, FB, RFC, MP, MM, FL, XD, NB, LC, LD, CB, AL, SF, ER, IP report no conflict of interest related to this study. AP has received honorary as consultant and Advisory Board for Genzyme and Amicus Ther. S.R. has received honorary as consultant and Advisory Board for Genzyme, Amicus Ther and Astellas. FS is a consultant for Roche.

Auteurs

Leonardo Barzaghi (L)

Department of Mathematics, University of Pavia, Via Ferrata 5, 27100 Pavia, Italy; Advanced Imaging and Artificial Intelligence Center, Department of Neuroradiology, IRCCS Mondino, Foundation, Via Mondino 2, 27100 Pavia, Italy; INFN, Istituto Nazionale di Fisica Nucleare, Pavia Unit, Via Bassi 6, 27100, Pavia, Italy. Electronic address: leonardo.barzaghi01@universitadipavia.it.

Francesca Brero (F)

INFN, Istituto Nazionale di Fisica Nucleare, Pavia Unit, Via Bassi 6, 27100, Pavia, Italy; Department of Physics, University of Pavia, Via Bassi 6, 27100, Pavia, Italy.

Raffaella Fiamma Cabini (RF)

Department of Mathematics, University of Pavia, Via Ferrata 5, 27100 Pavia, Italy; INFN, Istituto Nazionale di Fisica Nucleare, Pavia Unit, Via Bassi 6, 27100, Pavia, Italy; Euler Institute, Università della Svizzera Italiana, Via la Santa 1, 6962 Lugano, Switzerland.

Matteo Paoletti (M)

Advanced Imaging and Artificial Intelligence Center, Department of Neuroradiology, IRCCS Mondino, Foundation, Via Mondino 2, 27100 Pavia, Italy.

Mauro Monforte (M)

UOC di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Francesca Lizzi (F)

INFN, Istituto Nazionale di Fisica Nucleare, Pisa Unit, Largo Bruno Pontecorvo, 3, 56127 Pisa PI, Italy.

Francesco Santini (F)

Department of Radiology, University Hospital Basel, Basel, Switzerland; Basel Muscle MRI, Department of Biomedical Engineering, University of Basel, Basel, Switzerland.

Xeni Deligianni (X)

Department of Radiology, University Hospital Basel, Basel, Switzerland; Basel Muscle MRI, Department of Biomedical Engineering, University of Basel, Basel, Switzerland.

Niels Bergsland (N)

Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, Buffalo Neuroimaging Analysis Center, University of Buffalo, The State University of New York, Buffalo, NY, United State; IRCCS, Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy.

Sabrina Ravaglia (S)

Neuroncology/Neuroinflammation Unit, IRCCS Mondino Foundation.

Lorenzo Cavagna (L)

Division of Rheumatology, University and IRCCS Policlinico S. Matteo Foudation, Pavia, Italy.

Luca Diamanti (L)

Neuroncology/Neuroinflammation Unit, IRCCS Mondino Foundation.

Chiara Bonizzoni (C)

Advanced Imaging and Artificial Intelligence Center, Department of Neuroradiology, IRCCS Mondino, Foundation, Via Mondino 2, 27100 Pavia, Italy.

Alessandro Lascialfari (A)

INFN, Istituto Nazionale di Fisica Nucleare, Pavia Unit, Via Bassi 6, 27100, Pavia, Italy; Department of Physics, University of Pavia, Via Bassi 6, 27100, Pavia, Italy.

Silvia Figini (S)

Department of Social and Political Science, University of Pavia, Corso Carlo Alberto 3, 27100 Pavia, Italy; BioData Science Center, IRCCS Mondino Foundation, Pavia, Italy.

Enzo Ricci (E)

UOC di Neurologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Ian Postuma (I)

INFN, Istituto Nazionale di Fisica Nucleare, Pavia Unit, Via Bassi 6, 27100, Pavia, Italy; Department of Physics, University of Pavia, Via Bassi 6, 27100, Pavia, Italy.

Anna Pichiecchio (A)

Advanced Imaging and Artificial Intelligence Center, Department of Neuroradiology, IRCCS Mondino, Foundation, Via Mondino 2, 27100 Pavia, Italy; Department of Brain and Behavioural Sciences, University of Pavia, Via Mondino 2, 27100 Pavia, Italy.

Classifications MeSH