Biomechanical evaluation of an experimental internal ring fixator (RingFix) for stabilization of pelvic ring injuries on an osteoporotic bone model.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
06 Sep 2024
Historique:
received: 28 02 2024
accepted: 26 08 2024
medline: 7 9 2024
pubmed: 7 9 2024
entrez: 6 9 2024
Statut: epublish

Résumé

During the last decades, effective pain reduction and early mobilization were identified as the central priorities in therapy of insufficiency fractures of the pelvis. For operative treatment minimally-invasive stabilization techniques are favored. While there is consensus on the significance of sufficient dorsal stabilization the role of additional fixation of the anterior fracture component stays under discussion. Within the present study we developed an internal ring fixator system (RingFix) with the question whether an in-itself-closed construct can improve stability of the entire ring structure. RingFix was evaluated on an osteoporotic bone model with a standardized FFP IIIc fracture within an established biomechanical setup regarding its primary stabilization potential. Further, it was compared to transiliac-transsacral screw fixation with and without stabilization of the anterior fracture component. The transiliac-transsacral fixation with separate screw fixation of the anterior fracture showed significantly higher stability than the RingFix and the transiliac-transsacral screw fixation without anterior stabilization. Our results show that stabilization of the anterior fracture component relevantly improves the stability of the entire ring construct. As a bridging stabilizer, RingFix shows biomechanical advantages over an isolated dorsal fracture fixation, but inferior results than direct stabilization of the single fracture components.

Identifiants

pubmed: 39242670
doi: 10.1038/s41598-024-71138-3
pii: 10.1038/s41598-024-71138-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

20823

Subventions

Organisme : Mainzer Trauma-Stiftung
ID : 2018-01

Informations de copyright

© 2024. The Author(s).

Références

Heiman, E. et al. Fragility fractures of the pelvis and sacrum: Current trends in literature. Hip Pelvis 34(2), 69–78 (2022).
doi: 10.5371/hp.2022.34.2.69 pubmed: 35800130 pmcid: 9204239
Wilson, D. G. G., Kelly, J. & Rickman, M. Operative management of fragility fractures of the pelvis - a systematic review. BMC Musculoskel. Disord. 22(1), 717 (2021).
doi: 10.1186/s12891-021-04579-w
Rommens, P. M. & Hofmann, A. Comprehensive classification of fragility fractures of the pelvic ring: Recommendations for surgical treatment. Injury 44(12), 1733–1744 (2013).
doi: 10.1016/j.injury.2013.06.023 pubmed: 23871193
Krappinger, D., Kaser, V., Merkel, A., Neururer, S. & Lindtner, R. A. An alphanumeric classification of osteoporotic pelvic ring injuries. Arch. Orthop. Trauma Surg. 141(5), 861–869 (2021).
doi: 10.1007/s00402-020-03546-9 pubmed: 32737571
Ullrich, B. W. et al. OF-Pelvis classification of osteoporotic sacral and pelvic ring fractures. BMC Musculoskel. Disord. 22(1), 992 (2021).
doi: 10.1186/s12891-021-04882-6
Rommens, P. M. et al. Prospective assessment of key factors influencing treatment strategy and outcome of fragility fractures of the pelvis (FFP). Eur. J. Trauma Emerg. Surg. 48(4), 3243–3256 (2022).
doi: 10.1007/s00068-022-01887-1 pubmed: 35122506 pmcid: 9360063
van Zwienen, C. M., van den Bosch, E. W., Snijders, C. J., Kleinrensink, G. J. & van Vugt, A. B. Biomechanical comparison of sacroiliac screw techniques for unstable pelvic ring fractures. J. Orthop. Trauma 18(9), 589–595 (2004).
doi: 10.1097/00005131-200410000-00002 pubmed: 15448446
Hartensuer, R. et al. Safety, effect and feasibility of percutaneous SI-screw with and without augmentation-a 15-year retrospective analysis on over 640 screws. J. Clin. Med. 9(8), 2660 (2020).
doi: 10.3390/jcm9082660 pubmed: 32824548 pmcid: 7463525
Zderic, I. et al. Screw-in-screw fixation of fragility sacrum fractures provides high stability without loosening-biomechanical evaluation of a new concept. J. Orthop. Res. 39(4), 761–770 (2021).
doi: 10.1002/jor.24895 pubmed: 33098585
Mehling, I., Hessmann, M. H. & Rommens, P. M. Stabilization of fatigue fractures of the dorsal pelvis with a trans-sacral bar. Operative technique and outcome. Injury 43(4), 446–451 (2012).
doi: 10.1016/j.injury.2011.08.005 pubmed: 21889141
Sciubba, D. M. et al. CT fluoroscopically guided percutaneous placement of transiliosacral rod for sacral insufficiency fracture: Case report and technique. AJNR Am. J. Neuroradiol. 28(8), 1451–1454 (2007).
doi: 10.3174/ajnr.A0665 pubmed: 17846189 pmcid: 8134396
Wagner, D. et al. Trans-sacral bar osteosynthesis provides low mortality and high mobility in patients with fragility fractures of the pelvis. Sci. Rep. 11(1), 14201 (2021).
doi: 10.1038/s41598-021-93559-0 pubmed: 34244526 pmcid: 8270908
Rommens, P. M. et al. Minimally invasive stabilization of fragility fractures of the pelvis with transsacral bar and retrograde transpubic screw. Oper. Orthop. Traumatol. 34(2), 153–171 (2022).
doi: 10.1007/s00064-022-00763-w pubmed: 35301551
Rommens, P. M. et al. Fragility fractures of the pelvis. Unfallchirurg. 122(6), 469–482 (2019).
doi: 10.1007/s00113-019-0643-7 pubmed: 30980097
Muller, F. & Fuchtmeier, B. A systematic review of the transiliac internal fixator (TIFI) for posterior pelvic injuries. SICOT J. 7, 40 (2021).
doi: 10.1051/sicotj/2021037 pubmed: 34309508 pmcid: 8312281
Arand, C. et al. Do we need to fix the anterior fracture component in insufficiency fractures of the pelvis? A biomechanical comparison on an FFP type IIIc fracture in an osteoporotic pelvic bone model. Injury 54, 111096 (2023).
doi: 10.1016/j.injury.2023.111096 pubmed: 37833233
Yin, Y. et al. Anterior subcutaneous internal fixator (INFIX) versus plate fixation for pelvic anterior ring fracture. Sci. Rep. 9(1), 2578 (2019).
doi: 10.1038/s41598-019-39068-7 pubmed: 30796253 pmcid: 6385294
Apivatthakakul, T. & Rujiwattanapong, N. Anterior subcutaneous pelvic internal fixator (INFIX), Is it safe? A cadaveric study. Injury 47(10), 2077–2080 (2016).
doi: 10.1016/j.injury.2016.08.006 pubmed: 27546721
Schuetze, K. et al. Short-term outcome of fragility fractures of the pelvis in the elderly treated with screw osteosynthesis and external fixator. Eur. J. Trauma Emerg. Surg. 48(3), 2413–2420 (2022).
doi: 10.1007/s00068-021-01780-3 pubmed: 34545420
Rommens, P. M. et al. Minimal-invasive stabilization of anterior pelvic ring fractures with retrograde transpubic screws. Injury 51(2), 340–346. https://doi.org/10.1016/j.injury.2019.12.018 (2020).
doi: 10.1016/j.injury.2019.12.018 pubmed: 31879175
Mosheiff, R. & Liebergall, M. Maneuvering the retrograde medullary screw in pubic ramus fractures. J. Orthop. Trauma 16(8), 594–596 (2002).
doi: 10.1097/00005131-200209000-00009 pubmed: 12352569
Herteleer, M., Boudissa, M., Hofmann, A., Wagner, D. & Rommens, P. M. Plate fixation of the anterior pelvic ring in patients with fragility fractures of the pelvis. Eur. J. Trauma Emerg. Surg. 48(5), 3711–3719 (2022).
doi: 10.1007/s00068-021-01625-z pubmed: 33693977
Starr, A. J., Nakatani, T., Reinert, C. M. & Cederberg, K. Superior pubic ramus fractures fixed with percutaneous screws: What predicts fixation failure?. J. Orthop. Trauma 22(2), 81–87 (2008).
doi: 10.1097/BOT.0b013e318162ab6e pubmed: 18349774
Dalstra, M. & Huiskes, R. Load transfer across the pelvic bone. J. Biomech. 28(6), 715–724 (1995).
doi: 10.1016/0021-9290(94)00125-N pubmed: 7601870
Kramers-de Quervain, I. A. Ganganalyse beim Gehen und Laufen. Schweiz. Z. Sportmed. Sporttraumatol. 56(2), 35–42 (2008).
Rommens, P. M. et al. Clinical pathways for fragility fractures of the pelvic ring: Personal experience and review of the literature. J. Orthop. Sci. 20(1), 1–11 (2015).
doi: 10.1007/s00776-014-0653-9 pubmed: 25323921
Cintean, R. et al. Sacroiliac versus transiliac–transsacral screw osteosynthesis in osteoporotic pelvic fractures: A biomechanical comparison. Eur. J. Trauma Emerg. Surg. 49(6), 2553–2560. https://doi.org/10.1007/s00068-023-02341-6 (2023).
doi: 10.1007/s00068-023-02341-6 pubmed: 37535095 pmcid: 10728224
Dienstknecht, T. et al. Biomechanical analysis of a transiliac internal fixator. Int. Orthop. 35(12), 1863–1868 (2011).
doi: 10.1007/s00264-011-1251-5 pubmed: 21475979 pmcid: 3224620
El-Hamalawy, A. G., Karim, M. A., Khaled, S. A., Khaled Fawzy, M. & Abdel-Kader, E. K. Minimally invasive stabilization of posterior pelvic ring injuries through transiliac internal fixator versus Iliosacral screw: A prospective comparative cohort study. Injury 54(6), 1677–1686. https://doi.org/10.1016/j.injury.2023.02.042 (2023).
doi: 10.1016/j.injury.2023.02.042
Salasek, M., Jansova, M., Kren, J., Pavelka, T. & Weisova, D. Biomechanical comparison of a transiliac internal fixator and two iliosacral screws in transforaminal sacral fractures: A finite element analysis. Acta Bioeng. Biomech. 17(1), 39–49 (2015).
pubmed: 25952554
Wagner, D. et al. Space available for trans-sacral implants to treat fractures of the pelvis assessed by virtual implant positioning. Arch. Orthop. Trauma Surg. 139(10), 1385–1391 (2019).
doi: 10.1007/s00402-019-03204-9 pubmed: 31111201
Wagner, D. et al. Morphometry of the sacrum and its implication on trans-sacral corridors using a computed tomography data-based three-dimensional statistical model. Spine J. 17(8), 1141–1147 (2017).
doi: 10.1016/j.spinee.2017.03.023 pubmed: 28373081
Hopf, J. C., Krieglstein, C. F., Muller, L. P. & Koslowsky, T. C. Percutaneous iliosacral screw fixation after osteoporotic posterior ring fractures of the pelvis reduces pain significantly in elderly patients. Injury 46(8), 1631–1636 (2015).
doi: 10.1016/j.injury.2015.04.036 pubmed: 26052052
Osterhoff, G. et al. The pectineal ligament is a secondary stabilizer in anterior pelvic ring fractures - a biomechanical study. Injury 53(2), 334–338 (2022).
doi: 10.1016/j.injury.2021.12.006 pubmed: 34920874
Palmer, S., Fairbank, A. C. & Bircher, M. Surgical complications and implications of external fixation of pelvic fractures. Injury 28(9–10), 649–653 (1997).
doi: 10.1016/S0020-1383(97)00141-1 pubmed: 9624345
Hack, J. et al. Stability of internal versus external fixation in osteoporotic pelvic fractures - a biomechanical analysis. Injury 51(11), 2460–2464 (2020).
doi: 10.1016/j.injury.2020.08.017 pubmed: 32800315
Fang, C., Alabdulrahman, H. & Pape, H. C. Complications after percutaneous internal fixator for anterior pelvic ring injuries. Int. Orthop. 41(9), 1785–1790 (2017).
doi: 10.1007/s00264-017-3415-4 pubmed: 28236073
Hesse, D. et al. Femoral nerve palsy after pelvic fracture treated with INFIX: A case series. J. Orthop. Trauma 29(3), 138–143 (2015).
doi: 10.1097/BOT.0000000000000193 pubmed: 24983430
Arduini, M., Saturnino, L., Piperno, A., Iundusi, R. & Tarantino, U. Fragility fractures of the pelvis: Treatment and preliminary results. Aging Clin. Exp. Res. 27(Suppl 1), S61–S67 (2015).
doi: 10.1007/s40520-015-0430-4 pubmed: 26264247
Arand, C. et al. Anatomical evaluation of the transpubic screw corridor based on a 3D statistical model of the pelvic ring. Sci. Rep. 11(1), 16677 (2021).
doi: 10.1038/s41598-021-96219-5 pubmed: 34404906 pmcid: 8371146

Auteurs

Charlotte Arand (C)

Department of Orthopaedics and Traumatology, University Medical Center, Langenbeckstraße 1, 55131, Mainz, Germany. charlotte.arand@unimedizin-mainz.de.

Christian Hartung (C)

Department of Orthopaedics and Traumatology, University Medical Center, Langenbeckstraße 1, 55131, Mainz, Germany.

Dorothea Mehler (D)

Department of Orthopaedics and Traumatology, University Medical Center, Langenbeckstraße 1, 55131, Mainz, Germany.

Erol Gercek (E)

Department of Orthopaedics and Traumatology, University Medical Center, Langenbeckstraße 1, 55131, Mainz, Germany.

Jochen Wollstädter (J)

Department of Orthopaedics and Traumatology, University Medical Center, Langenbeckstraße 1, 55131, Mainz, Germany.

Daniel Wagner (D)

Departement of Orthopedics and Tramatology, Lausanne University Hospital, Rue du Bugnon 46, 1011, Lausanne, Switzerland.

Pol M Rommens (PM)

Department of Orthopaedics and Traumatology, University Medical Center, Langenbeckstraße 1, 55131, Mainz, Germany.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH