Surgical Management of Gestational Trophoblastic Neoplasia.

Choriocarcinoma Curettage Epithelioid trophoblastic tumor Gestational trophoblastic neoplasia Hysterectomy Metastatectomy Placental site trophoblastic tumor Surgery

Journal

Hematology/oncology clinics of North America
ISSN: 1558-1977
Titre abrégé: Hematol Oncol Clin North Am
Pays: United States
ID NLM: 8709473

Informations de publication

Date de publication:
06 Sep 2024
Historique:
medline: 8 9 2024
pubmed: 8 9 2024
entrez: 7 9 2024
Statut: aheadofprint

Résumé

Gestational trophoblastic neoplasia (GTN) is primarily treated with chemotherapy, but surgery plays a key role at different steps in disease management, including initial diagnosis, primary therapy, and salvage options. Initial diagnosis is usually made by electric or manual vacuum aspiration for molar pregancy or uterine curettage for other forms of GTN. Excisional procedures of localized disease, whether second curettage or hysterectomy, can obviate chemotherapy, but patients still require monitoring for relapse. Resection remains a useful adjunct for either the management of isolated foci of chemoresistant disease or the management of bleeding complications.

Identifiants

pubmed: 39244451
pii: S0889-8588(24)00083-2
doi: 10.1016/j.hoc.2024.07.006
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors report no financial disclosures related to this work.

Auteurs

Kevin M Elias (KM)

New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women's Hospital; Harvard Medical School, Boston, MA, USA; Dana-Farber Cancer Institute. Electronic address: kelias@bwh.harvard.edu.

Ross S Berkowitz (RS)

New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women's Hospital; Harvard Medical School, Boston, MA, USA; Dana-Farber Cancer Institute.

Neil S Horowitz (NS)

New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Reproductive Biology, Brigham and Women's Hospital; Harvard Medical School, Boston, MA, USA; Dana-Farber Cancer Institute.

Classifications MeSH