Uncovering possible silent acquired long QT syndrome using exercise stress testing in long-term pediatric acute lymphoblastic leukemia survivors.
LQTS
QT interval
childhood cancer survivors
exercise
Journal
International journal of cancer
ISSN: 1097-0215
Titre abrégé: Int J Cancer
Pays: United States
ID NLM: 0042124
Informations de publication
Date de publication:
08 Sep 2024
08 Sep 2024
Historique:
revised:
18
07
2024
received:
02
03
2024
accepted:
23
07
2024
medline:
8
9
2024
pubmed:
8
9
2024
entrez:
8
9
2024
Statut:
aheadofprint
Résumé
An example of chemotherapy-induced cardiotoxicity in cancer survivors is acquired long QT syndrome (aLQTS), which may cause serious yet preventable life-threatening consequences. Our objective was to identify and characterize childhood acute lymphoblastic leukemia (ALL) survivors with possible aLQTS using maximal exercise testing. In this cross-sectional study with exploratory analysis, a total of 250 childhood ALL survivors were evaluated for abnormal QT interval prolongation using the McMaster cycle exercise test. A total of 198 survivors (102 males; 96 females), having reached their
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Cancer Research Society
Organisme : Canadian Cancer Society Research Institute
Organisme : Pediatric Oncology Group of Ontario
Organisme : Garron Family Cancer Centre
Organisme : CIHR
Pays : Canada
Organisme : C17 Children's Cancer and Blood Disorders
Organisme : Ontario Institute for Cancer Research
Organisme : Cole Foundation, Fonds de Recherche du Québec - Santé (FRQS)
Organisme : Sainte-Justine University Hospital Center Foundation and Foundation of Stars
Organisme : Canada First Research Excellence Fund through the TransMedTech Institute
Informations de copyright
© 2024 The Author(s). International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC.
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