Hyperaldosteronism secondary to renal agenesis: An unusual cause for hypertension in pregnancy.

Eplerenone Pregnancy Renal agenesis Resistant hypertension Secondary hyperaldosteronism

Journal

Pregnancy hypertension
ISSN: 2210-7797
Titre abrégé: Pregnancy Hypertens
Pays: Netherlands
ID NLM: 101552483

Informations de publication

Date de publication:
07 Sep 2024
Historique:
received: 12 07 2024
accepted: 03 09 2024
medline: 8 9 2024
pubmed: 8 9 2024
entrez: 8 9 2024
Statut: aheadofprint

Résumé

Literature with regards to pregnancy related outcomes in persons with the presence of a solitary kidney of any cause is scarce. Most of the available information has been extrapolated from persons who have been renal donors. Unilateral renal agenesis affects 1 in 1500 people and can present with resistant hypertension. When a woman with a solitary kidney presents in pregnancy, it may be both a challenging diagnostic and therapeutic problem. Eplerenone, a selective aldosterone blocker has been prescribed for resistant hypertension and in the presence of pregnancy, been useful in persons with primary hyperaldosteronism and resistant hypertension due to obstructive sleep apnoea. We describe the use of Eplerenone in a patient with resistant hypertension in pregnancy, due to secondary hyperaldosteronism precipitated by renal agenesis.

Identifiants

pubmed: 39244817
pii: S2210-7789(24)00184-3
doi: 10.1016/j.preghy.2024.101157
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

101157

Informations de copyright

Copyright © 2024 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Nalini Newbigging (N)

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: nalini.newbigging@cmcvellore.ac.in.

Sowmya Sathyendra (S)

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Medicine Unit 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: sowmya@cmcvellore.ac.in.

Sudha Jasmine (S)

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Medicine Unit 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: sudhajasmine@cmcvellore.ac.in.

Liji S David (LS)

Obstetrics and Gynaecology Unit 4, Vellore, Tamil Nadu, India. Electronic address: Liji.David@cmcvellore.ac.in.

Audrin Lenin (A)

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Department of Medicine 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: audrinlenin@cmcvellore.ac.in.

Jennifer David Livingstone (J)

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Department of Medicine 3 and Obstetric Medicine, Vellore, Tamil Nadu, India. Electronic address: jennifer.david.pg@cmcvellore.ac.in.

Nihal Thomas (N)

Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: nihal_thomas@cmcvellore.ac.in.

Remya Rajan (R)

Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: remya.rajan@cmcvellore.ac.in.

Suceena Alexander (S)

Department of Nephrology Christian Medical College, Vellore, Tamil Nadu, India. Electronic address: suceena@cmcvellore.ac.in.

Classifications MeSH