Selective labelling of GBA2 in cells with fluorescent β-d-arabinofuranosyl cyclitol aziridines.

Journal

Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951

Informations de publication

Date de publication:
03 Sep 2024
Historique:
received: 16 11 2023
accepted: 28 08 2024
medline: 9 9 2024
pubmed: 9 9 2024
entrez: 9 9 2024
Statut: aheadofprint

Résumé

GBA2, the non-lysosomal β-glucosylceramidase, is an enzyme involved in glucosylceramide metabolism. Pharmacological inhibition of GBA2 by

Identifiants

DOI: 10.1039/d3sc06146a PMID: 39246358 PMC: PMC11375437
pubmed: 39246358
doi: 10.1039/d3sc06146a
pii: d3sc06146a
pmc: PMC11375437
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

There are no conflicts to declare.

Auteurs

Qin Su (Q)

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands j.m.f.g.aerts@lic.leidenuniv.nl m.e.artola@lic.leidenuniv.nl.
ORCID: 0000-0002-3333-8935

Max Louwerse (M)

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands j.m.f.g.aerts@lic.leidenuniv.nl m.e.artola@lic.leidenuniv.nl.
ORCID: 0000-0002-8584-9745

Rob F Lammers (RF)

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands j.m.f.g.aerts@lic.leidenuniv.nl m.e.artola@lic.leidenuniv.nl.
ORCID: 0000-0001-7237-2303

Elmer Maurits (E)

Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands.

Max Janssen (M)

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands j.m.f.g.aerts@lic.leidenuniv.nl m.e.artola@lic.leidenuniv.nl.

Rolf G Boot (RG)

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands j.m.f.g.aerts@lic.leidenuniv.nl m.e.artola@lic.leidenuniv.nl.

Valentina Borlandelli (V)

Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands.

Wendy A Offen (WA)

York Structural Biology Laboratory, Department of Chemistry, The University of York Heslington York YO10 5DD UK.

Daniël Linzel (D)

Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands.

Sybrin P Schröder (SP)

Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands.

Gideon J Davies (GJ)

York Structural Biology Laboratory, Department of Chemistry, The University of York Heslington York YO10 5DD UK.
ORCID: 0000-0002-7343-776X

Herman S Overkleeft (HS)

Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands.
ORCID: 0000-0001-6976-7005

Marta Artola (M)

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands j.m.f.g.aerts@lic.leidenuniv.nl m.e.artola@lic.leidenuniv.nl.
ORCID: 0000-0002-3051-3902

Johannes M F G Aerts (JMFG)

Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University P. O. Box 9502 2300 RA Leiden The Netherlands j.m.f.g.aerts@lic.leidenuniv.nl m.e.artola@lic.leidenuniv.nl.
ORCID: 0000-0001-8168-2565

Classifications MeSH