Differential utilization of thyroid lobectomy after the 2015 American Thyroid Association guideline update.

guideline adherence thyroid cancer thyroid lobectomy total thyroidectomy

Journal

Endocrine oncology (Bristol, England)
ISSN: 2634-4793
Titre abrégé: Endocr Oncol
Pays: England
ID NLM: 9918540584106676

Informations de publication

Date de publication:
01 Jan 2024
Historique:
received: 27 03 2024
accepted: 30 07 2024
medline: 9 9 2024
pubmed: 9 9 2024
entrez: 9 9 2024
Statut: epublish

Résumé

The 2015 American Thyroid Association (ATA) guidelines added thyroid lobectomy (TL) as the appropriate treatment for low-risk differentiated thyroid cancer (DTC). We aimed to investigate the population-level factors that influence the utilization of TL. The Surveillance, Epidemiology and End Results (SEER) database was queried for all DTC patients fitting low-risk criteria as defined by the ATA. Trends in total thyroidectomy (TT) and TL were identified using a Cochrane-Armitage test. Multivariable logistic regression identified patient and socioeconomic characteristics associated with TL, and difference-in-difference analysis was used to control for secular trends over time. A total of 43,526 patients with low-risk DTC were identified in the SEER database; 39,411 pre-2015 and 4115 post-2015. After 2015, TT continued to outnumber TL (76.2% vs 23.8%), although the rate of TL increased significantly (11.6% to 23.8%, Although the 2015 ATA guideline update led to an increase in TL for low-risk DTC, most patients still underwent TT. Age and neighborhood significantly impact the odds of receiving guideline-appropriate TL for low-risk DTC, especially for T2 disease.

Sections du résumé

Background UNASSIGNED
The 2015 American Thyroid Association (ATA) guidelines added thyroid lobectomy (TL) as the appropriate treatment for low-risk differentiated thyroid cancer (DTC). We aimed to investigate the population-level factors that influence the utilization of TL.
Methods UNASSIGNED
The Surveillance, Epidemiology and End Results (SEER) database was queried for all DTC patients fitting low-risk criteria as defined by the ATA. Trends in total thyroidectomy (TT) and TL were identified using a Cochrane-Armitage test. Multivariable logistic regression identified patient and socioeconomic characteristics associated with TL, and difference-in-difference analysis was used to control for secular trends over time.
Results UNASSIGNED
A total of 43,526 patients with low-risk DTC were identified in the SEER database; 39,411 pre-2015 and 4115 post-2015. After 2015, TT continued to outnumber TL (76.2% vs 23.8%), although the rate of TL increased significantly (11.6% to 23.8%,
Conclusion UNASSIGNED
Although the 2015 ATA guideline update led to an increase in TL for low-risk DTC, most patients still underwent TT. Age and neighborhood significantly impact the odds of receiving guideline-appropriate TL for low-risk DTC, especially for T2 disease.

Identifiants

pubmed: 39246628
doi: 10.1530/EO-24-0010
pii: EO-24-0010
pmc: PMC11378144
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e240010

Informations de copyright

© the author(s).

Déclaration de conflit d'intérêts

The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the study reported.

Auteurs

Patricia Gina Lu (PG)

Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA.

Zhi Ven Fong (Z)

Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA.

Patrick T Hangge (PT)

Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA.

Yu-Hui Chang (YH)

Department of Quantitative Health Sciences, Mayo Clinic in Arizona, Scottsdale, Arizona, USA.

Elisabeth S Lim (ES)

Department of Quantitative Health Sciences, Mayo Clinic in Arizona, Scottsdale, Arizona, USA.

Nabil Wasif (N)

Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA.

Patricia A Cronin (PA)

Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA.

Chee-Chee Stucky (CC)

Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA.

Classifications MeSH