High-fiber diet reduces bone formation but does not affect bone microarchitecture in type 2 diabetes individuals.
Wnt signaling
bone microarchitecture
bone turnover
glucose control
high-fiber diet
type 2 diabetes
Journal
JBMR plus
ISSN: 2473-4039
Titre abrégé: JBMR Plus
Pays: England
ID NLM: 101707013
Informations de publication
Date de publication:
Oct 2024
Oct 2024
Historique:
received:
21
03
2024
revised:
28
06
2024
accepted:
25
07
2024
medline:
10
9
2024
pubmed:
10
9
2024
entrez:
10
9
2024
Statut:
epublish
Résumé
Bone fragility is a recognized complication of type 2 diabetes mellitus (T2DM), increasing patient morbidity. Thus, the development of an effective intervention to prevent diabetic bone fragility is urgently needed. As lifestyle intervention represents an effective option for diabetes management, it may have an impact on bone health. While studies have shown a beneficial effect of dietary fiber in T2DM management, its effect on bone health is still unclear. Thus, we investigated the impact of a high-fiber diet on bone and glucose control in men and women with T2DM. Forty-five T2DM patients (HbA1c: 6.5% ± 0.49%, age: 74 ± 7.29 yr) scheduled for hip arthroplasty were randomly assigned to follow a high-fiber diet (38 g/day) or to make no diet changes for 12 wk. Interestingly, BMI decreased by 4% (
Identifiants
pubmed: 39253598
doi: 10.1093/jbmrpl/ziae111
pii: ziae111
pmc: PMC11382141
doi:
Types de publication
Journal Article
Langues
eng
Pagination
ziae111Informations de copyright
© The Author(s) 2024. Published by Oxford University Press on behalf of the American Society for Bone and Mineral Research.
Déclaration de conflit d'intérêts
The authors do not have any conflicts of interest to declare.