Factors associated with stellate ganglion block success in recurrent ventricular arrhythmias.

Stellate ganglion block Ventricular fibrillation Ventricular tachycardia

Journal

ESC heart failure
ISSN: 2055-5822
Titre abrégé: ESC Heart Fail
Pays: England
ID NLM: 101669191

Informations de publication

Date de publication:
10 Sep 2024
Historique:
revised: 19 08 2024
received: 14 04 2024
accepted: 24 08 2024
medline: 10 9 2024
pubmed: 10 9 2024
entrez: 10 9 2024
Statut: aheadofprint

Résumé

One treatment option for refractory ventricular arrythmias is stellate ganglion block (SGB). We examined differences in SGB success by patient and arrhythmia characteristics and predictors of successful SGB. This was a multicenter analysis of patients treated for refractory ventricular arrythmias in the Czech Republic and the United States. The primary outcome was absence of ventricular arrythmias at 24 h post SGB. SGB effectiveness was examined according to aetiology of cardiomyopathy, arrhythmia type, laterality of SGB, presence of inotropes, and presence of mechanical circulatory support. Binary logistic regression was used to examine variables associated with the primary outcome. In total there were 117 patients with refractory ventricular arrythmias treated with SGB. Overall, the mean age was 63.5 ± 11.0 years, majority of patients were male (94.0%), White (87.2%), and had an implantable cardioverter defibrillator in situ (70.1%). There were no differences in efficacy of SGB based on aetiology of cardiomyopathy (P = 0.623), arrhythmia type (0.852), laterality of block (P = 0.131), and presence of inotropes (P = 0.083). Multivariable analysis demonstrated that increased age was associated with decreased odds of SGB success (odds ratio: 0.96, confidence interval: 0.92-0.99, P = 0.039) whereas increased left ventricular ejection fraction trended towards increased odds of SGB success (odds ratio: 1.05, confidence interval: 0.995-1.11, P = 0.077). In this multicentre experience, SGB was similarly effective despite the aetiology of cardiomyopathy, type of arrhythmia, laterality, and inotropic or mechanical support. SGB was less effective for the suppression of ventricular arrythmias at 24 h for the elderly.

Identifiants

pubmed: 39253899
doi: 10.1002/ehf2.15072
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 The Author(s). ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

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Auteurs

Fouad Chouairi (F)

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Marat Fudim (M)

Department of Internal Medicine, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA.
Duke Clinical Research Institute, Durham, North Carolina, USA.

Ales Benak (A)

Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

Jonathan P Piccini (JP)

Department of Internal Medicine, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA.
Duke Clinical Research Institute, Durham, North Carolina, USA.

Jakub Toman (J)

Department of Internal Medicine, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA.

Josef Kautzner (J)

Department of Internal Medicine, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA.

Arun Ganesh (A)

Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, USA.

Marek Sramko (M)

Department of Internal Medicine, Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, USA.

Classifications MeSH