Comparison of the risk of pneumothorax in COVID-19 and seasonal influenza.
Humans
COVID-19
/ complications
Pneumothorax
/ etiology
Influenza, Human
/ complications
Male
Female
Middle Aged
Retrospective Studies
Republic of Korea
/ epidemiology
Aged
Adult
SARS-CoV-2
/ isolation & purification
Risk Factors
Hospitalization
Proportional Hazards Models
Seasons
Young Adult
Aged, 80 and over
COVID-19
Chronic lung disease
Influenza
Pneumonia
Pneumothorax
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
10 Sep 2024
10 Sep 2024
Historique:
received:
02
06
2024
accepted:
02
08
2024
medline:
11
9
2024
pubmed:
11
9
2024
entrez:
10
9
2024
Statut:
epublish
Résumé
Limited evidence exists regarding the link between coronavirus disease 2019 (COVID-19) and pneumothorax. Therefore, we aimed to evaluate the occurrence rate of pneumothorax in hospitalized patients with COVID-19 and compare the risk of pneumothorax between patients with COVID-19 and influenza. This retrospective cohort study used patient data from the National Health Insurance Service of South Korea. Patients diagnosed with COVID-19 (December 2019 to December 2021) and influenza (January 2019 to December 2021) who required hospitalization and respiratory support were included. We identified 46,460 patients with COVID-19 and 6,117 with influenza. The occurrence rate of pneumothorax was 0.74% in patients with COVID-19. In an inverse probability of treatment weighting matched cohort, the Cox proportional hazards regression model showed that COVID-19 was not associated with an increased risk of pneumothorax compared to influenza (hazard ratio, 1.22; 95% confidence interval, 0.75-1.99). However, the risk of pneumothorax associated with COVID-19 compared to influenza was significantly higher in patients without chronic lung disease than in those with (P for heterogeneity = 0.037). In conclusion, COVID-19, compared with influenza, is not associated with an increased risk of pneumothorax; however, it is associated with an increased risk in patients without chronic lung disease.
Identifiants
pubmed: 39256438
doi: 10.1038/s41598-024-69266-x
pii: 10.1038/s41598-024-69266-x
doi:
Types de publication
Journal Article
Comparative Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
21077Subventions
Organisme : National Research Foundation of Korea
ID : NRF-2021R1A5A2030333
Informations de copyright
© 2024. The Author(s).
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