Pesticides and pollinator brain: How do neonicotinoids affect the central nervous system of bees?

brain central nervous system honey bees neonicotinoids pesticides pollinators

Journal

The European journal of neuroscience

ISSN: 1460-9568

Titre abrégé: Eur J Neurosci

Pays: France

ID NLM: 8918110

Informations de publication

Date de publication:
11 Sep 2024

Historique:

revised: 11 08 2024

received: 03 05 2024

accepted: 29 08 2024

medline: 11 9 2024

pubmed: 11 9 2024

entrez: 11 9 2024

Statut: aheadofprint

Résumé

Neonicotinoids represent over a quarter of the global pesticide market. Research on their environmental impact has revealed their adverse effect on the cognitive functions of pollinators, in particular of bees. Cognitive impairments, mostly revealed by behavioural studies, are the phenotypic expression of an alteration in the underlying neural circuits, a matter deserving greater attention. Here, we reviewed studies on the impact of field-relevant doses of neonicotinoids on the neurophysiology and neurodevelopment of bees. In particular, we focus on their olfactory system as much knowledge has been gained on the different brain areas that participate in odour processing. Recent studies have revealed the detrimental effects of neonicotinoids at multiple levels of the olfactory system, including modulation of odorant-induced activity in olfactory sensory neurons, diminished neural responses in the antennal lobe (the first olfactory processing centre) and abnormal development of the neural connectivity within the mushroom bodies (central neuropils involved in multisensory integration, learning and memory storage, among others). Given the importance of olfactory perception for multiple aspects of bee biology, the reported disruption of the olfactory circuit, which can occur even upon exposure to sublethal doses of neonicotinoids, has severe consequences at both individual and colony levels. Moreover, the effects reported for a multimodal structure such as the mushroom bodies indicate that neonicotinoids' impact translates to other sensory domains. Assessing the impact of field-relevant doses of pesticides on bee neurophysiology is crucial for understanding how neonicotinoids influence their behaviour in ecological contexts and for defining effective and sustainable agricultural practices.

Identifiants

DOI: 10.1111/ejn.16536 PMID: 39258341

pubmed: 39258341

doi: 10.1111/ejn.16536

doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

Subventions

Organisme : Sorbonne Université

ID : Funding allocated to M. Giurfa

Organisme : Institut Universitaire de France

ID : IUF Chair of M. Giurfa

Organisme : Sorbonne University

Informations de copyright

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