Subcortical Aphasia: An Update.

Basal ganglia Connectivity studies Neuroimaging Subcortical aphasia Thalamus Tractography

Journal

Current neurology and neuroscience reports

ISSN: 1534-6293

Titre abrégé: Curr Neurol Neurosci Rep

Pays: United States

ID NLM: 100931790

Informations de publication

Date de publication:
11 Sep 2024

Historique:

accepted: 19 08 2024

medline: 11 9 2024

pubmed: 11 9 2024

entrez: 11 9 2024

Statut: aheadofprint

Résumé

This review aims to rediscuss the leading theories concerning the role of basal ganglia and the thalamus in the genesis of aphasic symptoms in the absence of gross anatomical lesions in cortical language areas as assessed by conventional neuroimaging studies. New concepts in language processing and modern neuroimaging techniques have enabled some progress in resolving the impasse between the current dominant theories: (a) direct and specific linguistic processing and (b) subcortical structures as processing relays in domain-general functions. Of particular interest are studies of connectivity based on functional magnetic resonance imaging (MRI) and tractography that highlight the impact of white matter pathway lesions on aphasia development and recovery. Connectivity studies have put into evidence the central role of the arcuate fasciculus (AF), inferior frontal occipital fasciculus (IFOF), and uncinate fasciculus (UF) in the genesis of aphasia. Regarding the thalamus, its involvement in lexical-semantic processing through modulation of the frontal cortex is becoming increasingly apparent.

Identifiants

DOI: 10.1007/s11910-024-01373-8 PMID: 39259429

pubmed: 39259429

doi: 10.1007/s11910-024-01373-8

pii: 10.1007/s11910-024-01373-8

doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

Informations de copyright

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