A case of Bartonella vinsonii endocarditis.

Bartonella Diagnosis Infective endocarditis Metagenomic next generation sequencing (m-NGS)

Journal

Diagnostic microbiology and infectious disease
ISSN: 1879-0070
Titre abrégé: Diagn Microbiol Infect Dis
Pays: United States
ID NLM: 8305899

Informations de publication

Date de publication:
07 Sep 2024
Historique:
received: 05 08 2024
revised: 21 08 2024
accepted: 06 09 2024
medline: 11 9 2024
pubmed: 11 9 2024
entrez: 11 9 2024
Statut: aheadofprint

Résumé

The diagnosis of Bartonella is challenging due to its rarity and negative culture results. Once the diagnosis is delayed and proper treatment is not given, it can develop into infective endocarditis, which can be fatal. We reported a 60-year-old female patient who had recurrent fever for 5 months. After receiving ineffective treatment at the local hospital, she sought medical attention at our hospital. Laboratory blood indicators testing and imaging indicated infective endocarditis, and metagenomic Next Generation Sequencing (m-NGS) testing confirmed the diagnosis of Bartonella vinsonii infection. After surgical treatment and the combination of doxycycline and ceftriaxone sodium for anti-infective therapy, the patient recovered. Valuing the combination of multiple auxiliary diagnostic methods and improving the application of m-NGS in the detection of unknown pathogens can compensate for the current limitations in the diagnosis of Bartonella. Early diagnosis and treatment are extremely important for Bartonella endocarditis.

Identifiants

pubmed: 39260018
pii: S0732-8893(24)00360-2
doi: 10.1016/j.diagmicrobio.2024.116535
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

116535

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Mengyuan Chen (M)

The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China.

Yongjian Chen (Y)

Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, 310014, China.

Xueqian He (X)

Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, 310014, China.

Rongrong Hao (R)

Zhejiang Provincial Center for Medical Science Technology and Education Development, Hangzhou, Zhejiang, 310006, China.

Xuxia Jiang (X)

The Third People's Hospital of Xiaoshan Hangzhou, Hangzhou, Zhejiang, 311251, China.

Youqi Ji (Y)

School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.

Bingqian Zhuo (B)

Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, 310014, China.

Wei Xu (W)

School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.

Rui Lin (R)

Zhejiang Provincial People's Hospital Bijie Hospital, Bijie, Guizhou, 551700, China.

Yumei Ge (Y)

Department of Clinical Laboratory, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, 310014, China. Electronic address: 11218070@zju.edu.cn.

Classifications MeSH