Influence of acclimatization time on barometric whole-body plethysmography in cats with lower airway disease.
bronchial disease
bronchitis
feline asthma
lung function testing
Journal
Journal of veterinary internal medicine
ISSN: 1939-1676
Titre abrégé: J Vet Intern Med
Pays: United States
ID NLM: 8708660
Informations de publication
Date de publication:
11 Sep 2024
11 Sep 2024
Historique:
received:
12
12
2023
accepted:
10
07
2024
medline:
12
9
2024
pubmed:
12
9
2024
entrez:
12
9
2024
Statut:
aheadofprint
Résumé
Barometric whole-body plethysmography (BWBP) is used as a noninvasive method to assess lung function in cats with lower airway disease (LAD). The duration of the acclimatization period in the measuring chamber varies between the studies. To assess the influence of acclimatization time on variables indicative of lung function. Twenty-four client-owned cats with LAD and 8 healthy cats. In the prospective case-control study for each cat, a 30-minute dataset was collected. Data for the three 10-minute periods were statistically compared. The variables pause (T1 median: 0.8, range: [0.7-1]; T3: 0.9 [0.8-1.1]; P ≤ .01), peak inspiratory flow (PIF; T1: 84.9 [71.6-112.7]; T3: 75 [63.6-108.3]; P ≤ .001), peak expiratory flow (PEF; T1: 53.2 [41.5-76.6]; T3: 42.5 [34.6-57.8]; P ≤ .01), and a quotient of PEF and expiratory flow at 50% expired volume (PEF/EF50; T1: 1.2 [1.1-1.4]; T3: 1.2 [1.1-1.5]; P ≤ .01) varied significantly between first and third time period in cats with LAD. In healthy cats PIF (T1: 76.4 [66.3-85.2]; T2: 69.5 [58.3-85.2]; P ≤ .01), PEF (T1: 40 [32.8-58.6]; T2: 34.3, [29.8-44.6]; P ≤ .01), and PEF/EF50 (T1: 13.1 [11.6-14.6]; T3: 13.6 [12.4-16.3]; P ≤ .01) changed significantly between first and second time period. Enhanced pause did not change significantly in either group. Acclimatization time has a significant influence on multiple variables in BWBP. Manual correction of the data for tidal breathing flow-volume loop might be necessary.
Sections du résumé
BACKGROUND
BACKGROUND
Barometric whole-body plethysmography (BWBP) is used as a noninvasive method to assess lung function in cats with lower airway disease (LAD). The duration of the acclimatization period in the measuring chamber varies between the studies.
OBJECTIVES
OBJECTIVE
To assess the influence of acclimatization time on variables indicative of lung function.
ANIMALS
METHODS
Twenty-four client-owned cats with LAD and 8 healthy cats.
METHODS
METHODS
In the prospective case-control study for each cat, a 30-minute dataset was collected. Data for the three 10-minute periods were statistically compared.
RESULTS
RESULTS
The variables pause (T1 median: 0.8, range: [0.7-1]; T3: 0.9 [0.8-1.1]; P ≤ .01), peak inspiratory flow (PIF; T1: 84.9 [71.6-112.7]; T3: 75 [63.6-108.3]; P ≤ .001), peak expiratory flow (PEF; T1: 53.2 [41.5-76.6]; T3: 42.5 [34.6-57.8]; P ≤ .01), and a quotient of PEF and expiratory flow at 50% expired volume (PEF/EF50; T1: 1.2 [1.1-1.4]; T3: 1.2 [1.1-1.5]; P ≤ .01) varied significantly between first and third time period in cats with LAD. In healthy cats PIF (T1: 76.4 [66.3-85.2]; T2: 69.5 [58.3-85.2]; P ≤ .01), PEF (T1: 40 [32.8-58.6]; T2: 34.3, [29.8-44.6]; P ≤ .01), and PEF/EF50 (T1: 13.1 [11.6-14.6]; T3: 13.6 [12.4-16.3]; P ≤ .01) changed significantly between first and second time period. Enhanced pause did not change significantly in either group.
CONCLUSIONS AND CLINICAL IMPORTANCE
CONCLUSIONS
Acclimatization time has a significant influence on multiple variables in BWBP. Manual correction of the data for tidal breathing flow-volume loop might be necessary.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024 The Author(s). Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.
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