Update on cutaneous mesenchymal tumors in the 5th edition of WHO classification of skin tumors with an emphasis on new fusion-associated neoplasms.
ACTIN::MITF
CRTC1::TRIM11 cutaneous tumor
EWSR1::SMAD3-rearranged fibroblastic tumor
MITF pathway–activated melanocytic tumors
MITF::CREM fusion
NTRK-rearranged spindle cell neoplasm
Superficial CD34+ fibroblastic tumor
Journal
Virchows Archiv : an international journal of pathology
ISSN: 1432-2307
Titre abrégé: Virchows Arch
Pays: Germany
ID NLM: 9423843
Informations de publication
Date de publication:
12 Sep 2024
12 Sep 2024
Historique:
received:
21
06
2024
accepted:
31
08
2024
revised:
27
08
2024
medline:
12
9
2024
pubmed:
12
9
2024
entrez:
12
9
2024
Statut:
aheadofprint
Résumé
The section on mesenchymal tumors in the 5th edition of WHO classification of skin tumors has undergone several changes, the most important of which is the inclusion of newly identified tumor entities, which will be the main focus of this review article. These specifically include three novel cutaneous mesenchymal tumors with melanocytic differentiation, and rearrangements of the CRTC1::TRIM11, ACTIN::MITF, and MITF::CREM genes as well as EWSR1::SMAD3-rearranged fibroblastic tumors, superficial CD34-positive fibroblastic tumors, and NTRK-rearranged spindle cell neoplasms. Some of the other most important changes will be briefly mentioned as well.
Identifiants
pubmed: 39264472
doi: 10.1007/s00428-024-03925-2
pii: 10.1007/s00428-024-03925-2
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministerstvo Školství, Mládeže a Tělovýchovy
ID : SVV 260652
Organisme : Cooperatio program
ID : Surg
Informations de copyright
© 2024. The Author(s).
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