Postoperative risk assessment of post-inflammatory hyperpigmentation and the efficacy of delayed prevention following 532 nm Q-switched Nd:YAG laser treatment of solar lentigines: a randomized controlled study.
Humans
Female
Lasers, Solid-State
/ therapeutic use
Lentigo
/ etiology
Male
Middle Aged
Hyperpigmentation
/ prevention & control
Risk Assessment
Aged
Single-Blind Method
Adult
Treatment Outcome
Skin Cream
/ administration & dosage
Sunlight
/ adverse effects
Emollients
/ administration & dosage
Risk Factors
Post-inflammatory hyperpigmentation
Q-switched Nd:YAG
prevention
risk assessment
solar lentigo
triple combination cream
Journal
The Journal of dermatological treatment
ISSN: 1471-1753
Titre abrégé: J Dermatolog Treat
Pays: England
ID NLM: 8918133
Informations de publication
Date de publication:
Dec 2024
Dec 2024
Historique:
medline:
13
9
2024
pubmed:
13
9
2024
entrez:
12
9
2024
Statut:
ppublish
Résumé
Although post-inflammatory hyperpigmentation (PIH) is a common adverse event following laser procedures, studies evaluating its risk remain limited. To analyze PIH risk after 532 nm Q-switched Nd:YAG laser (QSNYL) treatment for solar lentigines and examine the efficacy of triple combination cream (TCC) for its prevention. In this single center, investigator-blinded, randomized controlled study, participants with solar lentigo either received TCC or emollient from 2 weeks post-QSNYL treatment. The occurrence of PIH was determined by three independent and blinded dermatologists. A total of 28 patients with 67 solar lentigines were included in the analysis. In the control group, PIH occurred in 55.3% of the lesions. Risk factors for the occurrence of PIH were the increased erythema at weeks 2 (OR, 1.32; Post-laser erythema and outdoor activity at the daytime are prognostic factors for the occurrence of PIH. Administering TCC could be considered for the prevention of PIH in high-risk patients.
Sections du résumé
BACKGROUND
UNASSIGNED
Although post-inflammatory hyperpigmentation (PIH) is a common adverse event following laser procedures, studies evaluating its risk remain limited.
OBJECTIVE
UNASSIGNED
To analyze PIH risk after 532 nm Q-switched Nd:YAG laser (QSNYL) treatment for solar lentigines and examine the efficacy of triple combination cream (TCC) for its prevention.
METHODS
UNASSIGNED
In this single center, investigator-blinded, randomized controlled study, participants with solar lentigo either received TCC or emollient from 2 weeks post-QSNYL treatment. The occurrence of PIH was determined by three independent and blinded dermatologists.
RESULTS
UNASSIGNED
A total of 28 patients with 67 solar lentigines were included in the analysis. In the control group, PIH occurred in 55.3% of the lesions. Risk factors for the occurrence of PIH were the increased erythema at weeks 2 (OR, 1.32;
CONCLUSION
UNASSIGNED
Post-laser erythema and outdoor activity at the daytime are prognostic factors for the occurrence of PIH. Administering TCC could be considered for the prevention of PIH in high-risk patients.
Identifiants
pubmed: 39265567
doi: 10.1080/09546634.2024.2398768
doi:
Substances chimiques
Emollients
0
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM