The role of limb alignment on natural tibiofemoral kinematics and kinetics.


Journal

Bone & joint research
ISSN: 2046-3758
Titre abrégé: Bone Joint Res
Pays: England
ID NLM: 101586057

Informations de publication

Date de publication:
13 Sep 2024
Historique:
medline: 13 9 2024
pubmed: 13 9 2024
entrez: 12 9 2024
Statut: epublish

Résumé

This study aimed to analyze kinematics and kinetics of the tibiofemoral joint in healthy subjects with valgus, neutral, and varus limb alignment throughout multiple gait activities using dynamic videofluoroscopy. Five subjects with valgus, 12 with neutral, and ten with varus limb alignment were assessed during multiple complete cycles of level walking, downhill walking, and stair descent using a combination of dynamic videofluoroscopy, ground reaction force plates, and optical motion capture. Following 2D/3D registration, tibiofemoral kinematics and kinetics were compared between the three limb alignment groups. No significant differences for the rotational or translational patterns between the different limb alignment groups were found for level walking, downhill walking, or stair descent. Neutral and varus aligned subjects showed a mean centre of rotation located on the medial condyle for the loaded stance phase of all three gait activities. Valgus alignment, however, resulted in a centrally located centre of rotation for level and downhill walking, but a more medial centre of rotation during stair descent. Knee adduction/abduction moments were significantly influenced by limb alignment, with an increasing knee adduction moment from valgus through neutral to varus. Limb alignment was not reflected in the condylar kinematics, but did significantly affect the knee adduction moment. Variations in frontal plane limb alignment seem not to be a main modulator of condylar kinematics. The presented data provide insights into the influence of anatomical parameters on tibiofemoral kinematics and kinetics towards enhancing clinical decision-making and surgical restoration of natural knee joint motion and loading.

Identifiants

pubmed: 39266005
doi: 10.1302/2046-3758.139.BJR-2023-0162.R3
pii: BJR-2023-0162.R3
doi:

Types de publication

Journal Article

Langues

eng

Pagination

485-496

Subventions

Organisme : Medacta International SA
Organisme : Commission for Technology and Innovation

Informations de copyright

© 2024 Postolka et al.

Déclaration de conflit d'intérêts

This work was partially supported by the Commission for Technology and Innovation (Bern, Switzerland, Project Number 17078.1 PFLS-LS) and Medacta International SA (Castel San Pietro, Switzerland). Medacta was not involved in the data collection, nor in the analysis or the interpretation of the data. R. List and W. R. Taylor have previously received speaker’s fees from Medacta. S. F. Fucentese receives advisory fees from Medacta as part of his consultancy work, and receives consulting fees from Zimmer Biomet and Karl Storz, unrelated to this study. S. F. Fucentese is also a board member of EKA-ESSKA Osteotomy.

Références

Andriacchi TP , Alexander EJ , Toney MK , Dyrby C , Sum J . A point cluster method for in vivo motion analysis: applied to a study of knee kinematics . J Biomech Eng . 1998 ; 120 ( 6 ): 743 – 749 . 10.1115/1.2834888 10412458
Postolka B , Schütz P , Fucentese SF , et al. Tibio-femoral kinematics of the healthy knee joint throughout complete cycles of gait activities . J Biomech . 2020 ; 110 : 109915 . 10.1016/j.jbiomech.2020.109915 32827791
Gale T , Anderst W . Knee kinematics of healthy adults measured using biplane radiography . J Biomech Eng . 2020 ; 142 ( 10 ): 101004 . 10.1115/1.4047419 32491153
Li G , Kozanek M , Hosseini A , Liu F , Van de Velde SK , Rubash HE . New fluoroscopic imaging technique for investigation of 6DOF knee kinematics during treadmill gait . J Orthop Surg Res . 2009 ; 4 : 6 . 10.1186/1749-799X-4-6 19284658
Thomeer L , Guan S , Gray H , Schache A , de Steiger R , Pandy M . Six-degree-of-freedom tibiofemoral and patellofemoral joint motion during activities of daily living . Ann Biomed Eng . 2021 ; 49 ( 4 ): 1183 – 1198 . 10.1007/s10439-020-02646-2 33094419
Dennis D , Komistek R , Scuderi G , et al. In vivo three-dimensional determination of kinematics for subjects with a normal knee or a unicompartmental or total knee replacement . J Bone Joint Surg Am . 2001 ; 83-A Suppl 2 Pt 2 : 104 – 115 . 10.2106/00004623-200100022-00008 11712831
Koo S , Andriacchi TP . The knee joint center of rotation is predominantly on the lateral side during normal walking . J Biomech . 2008 ; 41 ( 6 ): 1269 – 1273 . 10.1016/j.jbiomech.2008.01.013 18313060
Koo YJ , Koo S . Three-dimensional kinematic coupling in the knee during normal walking . J Biomech Eng . 2019 ; 141 ( 8 ): 81012 . 31017635
Bellemans J , Colyn W , Vandenneucker H , Victor J . The Chitranjan Ranawat award: is neutral mechanical alignment normal for all patients? The concept of constitutional varus . Clin Orthop Relat Res . 2012 ; 470 ( 1 ): 45 – 53 . 10.1007/s11999-011-1936-5 21656315
MacDessi SJ , Griffiths-Jones W , Harris IA , Bellemans J , Chen DB . Coronal Plane Alignment of the Knee (CPAK) classification a new system for describing knee phenotypes . Bone Joint J . 2021 ; 103-B ( 2 ): 329 – 337 . 10.1302/0301-620X.103B2.BJJ-2020-1050.R1 33517740
Sharma L , Song J , Dunlop D , et al. Varus and valgus alignment and incident and progressive knee osteoarthritis . Ann Rheum Dis . 2010 ; 69 ( 11 ): 1940 – 1945 . 10.1136/ard.2010.129742 20511608
Hsu RW , Himeno S , Coventry MB , Chao EY . Normal axial alignment of the lower extremity and load-bearing distribution at the knee . Clin Orthop Relat Res . 1990 ; 255 : 215 – 227 . 2347155
Schipplein OD , Andriacchi TP . Interaction between active and passive knee stabilizers during level walking . J Orthop Res . 1991 ; 9 ( 1 ): 113 – 119 . 10.1002/jor.1100090114 1984041
Heller MO , Taylor WR , Perka C , Duda GN . The influence of alignment on the musculo-skeletal loading conditions at the knee . Langenbecks Arch Surg . 2003 ; 388 ( 5 ): 291 – 297 . 10.1007/s00423-003-0406-2 13680238
Van Rossom S , Wesseling M , Smith CR , et al. The influence of knee joint geometry and alignment on the tibiofemoral load distribution: a computational study . Knee . 2019 ; 26 ( 4 ): 813 – 823 . 10.1016/j.knee.2019.06.002 31255528
Maderbacher G , Baier C , Springorum HR , Zeman F , Grifka J , Keshmiri A . Lower limb anatomy and alignment affect natural tibiofemoral knee kinematics: a cadaveric investigation . J Arthroplasty . 2016 ; 31 ( 9 ): 2038 – 2042 . 10.1016/j.arth.2016.02.049 27017201
Baier C , Benditz A , Koeck F , Keshmiri A , Grifka J , Maderbacher G . Different kinematics of knees with varus and valgus deformities . J Knee Surg . 2018 ; 31 ( 3 ): 264 – 269 . 10.1055/s-0037-1603340 28561154
Turcot K , Armand S , Lübbeke A , Fritschy D , Hoffmeyer P , Suvà D . Does knee alignment influence gait in patients with severe knee osteoarthritis? Clin Biomech (Bristol, Avon) . 2013 ; 28 ( 1 ): 34 – 39 . 10.1016/j.clinbiomech.2012.09.004 23063098
Guggenberger R , Pfirrmann CWA , Koch PP , Buck FM . Assessment of lower limb length and alignment by biplanar linear radiography: comparison with supine CT and upright full-length radiography . AJR Am J Roentgenol . 2014 ; 202 ( 2 ): W161 – 7 . 10.2214/AJR.13.10782 24450698
World Medical Association . World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects . JAMA . 2013 ; 310 ( 20 ): 2191 – 2194 . 10.1001/jama.2013.281053 24141714
List R , Postolka B , Schütz P , et al. A moving fluoroscope to capture tibiofemoral kinematics during complete cycles of free level and downhill walking as well as stair descent . PLoS One . 2017 ; 12 ( 10 ): e0185952 . 10.1371/journal.pone.0185952 29016647
List R , Gülay T , Stoop M , Lorenzetti S . Kinematics of the trunk and the lower extremities during restricted and unrestricted squats . J Strength Cond Res . 2013 ; 27 ( 6 ): 1529 – 1538 . 10.1519/JSC.0b013e3182736034 22990570
Postolka B , Taylor WR , List R , Fucentese SF , Koch PP , Schütz P . ISB clinical biomechanics award winner 2021: Tibio-femoral kinematics of natural versus replaced knees – a comparison using dynamic videofluoroscopy . Clin Biomech (Bristol, Avon) . 2022 ; 96 : 105667 . 10.1016/j.clinbiomech.2022.105667 35636308
Pauchard Y , Fitze T , Browarnik D , et al. Interactive graph-cut segmentation for fast creation of finite element models from clinical ct data for hip fracture prediction . Comput Methods Biomech Biomed Engin . 2016 ; 19 ( 16 ): 1693 – 1703 . 10.1080/10255842.2016.1181173 27161828
Postolka B , List R , Thelen B , Schütz P , Taylor WR , Zheng G . Evaluation of an intensity-based algorithm for 2D/3D registration of natural knee videofluoroscopy data . Med Eng Phys . 2020 ; 77 : 107 – 113 . 10.1016/j.medengphy.2020.01.002 31980316
Ehrig RM , Taylor WR , Duda GN , Heller MO . A survey of formal methods for determining functional joint axes . J Biomech . 2007 ; 40 ( 10 ): 2150 – 2157 . 10.1016/j.jbiomech.2006.10.026 17169365
Grood ES , Suntay WJ . A joint coordinate system for the clinical description of three-dimensional motions: application to the knee . J Biomech Eng . 1983 ; 105 ( 2 ): 136 – 144 . 10.1115/1.3138397 6865355
Ehrig RM , Taylor WR , Duda GN , Heller MO . A survey of formal methods for determining the centre of rotation of ball joints . J Biomech . 2006 ; 39 ( 15 ): 2798 – 2809 . 10.1016/j.jbiomech.2005.10.002 16293257
Schütz P , List R , Zemp R , Schellenberg F , Taylor WR , Lorenzetti S . Joint angles of the ankle, knee, and hip and loading conditions during split squats . J Appl Biomech . 2014 ; 30 ( 3 ): 373 – 380 . 10.1123/jab.2013-0175 24345718
Durkin JL , Dowling JJ . Analysis of body segment parameter differences between four human populations and the estimation errors of four popular mathematical models . J Biomech Eng . 2003 ; 125 ( 4 ): 515 – 522 . 10.1115/1.1590359 12968576
Pataky TC , Robinson MA , Vanrenterghem J . Region-of-interest analyses of one-dimensional biomechanical trajectories: bridging 0D and 1D theory, augmenting statistical power . PeerJ . 2016 ; 4 : e2652 . 10.7717/peerj.2652 27833816
Mündermann A , Dyrby CO , Andriacchi TP . Secondary gait changes in patients with medial compartment knee osteoarthritis: increased load at the ankle, knee, and hip during walking . Arthritis Rheum . 2005 ; 52 ( 9 ): 2835 – 2844 . 10.1002/art.21262 16145666
Hitz M , Schütz P , Angst M , Taylor WR , List R . Influence of the moving fluoroscope on gait patterns . PLoS One . 2018 ; 13 ( 7 ): e0200608 . 10.1371/journal.pone.0200608 30005086
Hosseini Nasab SH , Smith CR , Postolka B , Schütz P , List R , Taylor WR . In vivo elongation patterns of the collateral ligaments in healthy knees during functional activities . J Bone Joint Surg Am . 2021 ; 103-A ( 17 ): 1620 – 1627 . 10.2106/JBJS.20.01311 33848100

Auteurs

Barbara Postolka (B)

Laboratory for Movement Biomechanics, Institute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Human Movement Biomechanics Research Group, KU Leuven, Leuven, Belgium.

William R Taylor (WR)

Laboratory for Movement Biomechanics, Institute for Biomechanics, ETH Zürich, Zürich, Switzerland.

Sandro F Fucentese (SF)

Balgrist University Hospital, Zürich, Switzerland.

Renate List (R)

Laboratory for Movement Biomechanics, Institute for Biomechanics, ETH Zürich, Zürich, Switzerland.
Human Performance Lab, Schulthess Clinic, Zürich, Switzerland.

Pascal Schütz (P)

Laboratory for Movement Biomechanics, Institute for Biomechanics, ETH Zürich, Zürich, Switzerland.

Classifications MeSH