Coronary artery bypass grafting
Coronary artery bypass grafting (CABG)
coronary artery disease
health outcomes
percutaneous coronary intervention (PCI)
Journal
Journal of thoracic disease
ISSN: 2072-1439
Titre abrégé: J Thorac Dis
Pays: China
ID NLM: 101533916
Informations de publication
Date de publication:
31 Aug 2024
31 Aug 2024
Historique:
received:
20
02
2024
accepted:
31
05
2024
medline:
13
9
2024
pubmed:
13
9
2024
entrez:
13
9
2024
Statut:
ppublish
Résumé
Coronary artery bypass grafting (CABG) and drug-eluting stent implantation (DES) are established as central methods of revascularization for patients with coronary artery disease. This study aims to analyse the health trajectories of patients after first CABG or first, second or third DES within the first three years, with a focus on follow-up interventions, severe care need, transition into a nursing home, and death. Based on health claims data (n=11,581), we estimated age-and sex standardized probabilities of reintervention, and of transition to severe care need, nursing home and death following initial CABG (n=2,008) or DES (n=9,573) for patients aged 50 years and older using logistic regression models and direct standardization. Up to three follow-up DES interventions and one follow-up CABG were considered. There was a fairly high probability of reintervention, particularly after a DES and within the first year. Follow-up interventions were more likely to involve DES than CABG. The probability of death was notably higher for CABG patients. The probabilities of severe care need and moving to a nursing home were slightly lower and similar across the revascularization methods and over time. DES and CABG are often associated with a need for follow-up interventions. Depending on the procedure, however, the risk of repeat surgery or adverse health outcomes varies. DES is associated with a relatively high probability of follow-up revascularization and a nearly constant probability of negative health outcomes in the short and medium term. In contrast, within three years after a CABG, follow-up reinterventions are rather rare. However, this procedure is particularly associated with an increased risk of mortality and short-term transition into a nursing home.
Sections du résumé
Background
UNASSIGNED
Coronary artery bypass grafting (CABG) and drug-eluting stent implantation (DES) are established as central methods of revascularization for patients with coronary artery disease. This study aims to analyse the health trajectories of patients after first CABG or first, second or third DES within the first three years, with a focus on follow-up interventions, severe care need, transition into a nursing home, and death.
Methods
UNASSIGNED
Based on health claims data (n=11,581), we estimated age-and sex standardized probabilities of reintervention, and of transition to severe care need, nursing home and death following initial CABG (n=2,008) or DES (n=9,573) for patients aged 50 years and older using logistic regression models and direct standardization. Up to three follow-up DES interventions and one follow-up CABG were considered.
Results
UNASSIGNED
There was a fairly high probability of reintervention, particularly after a DES and within the first year. Follow-up interventions were more likely to involve DES than CABG. The probability of death was notably higher for CABG patients. The probabilities of severe care need and moving to a nursing home were slightly lower and similar across the revascularization methods and over time.
Conclusions
UNASSIGNED
DES and CABG are often associated with a need for follow-up interventions. Depending on the procedure, however, the risk of repeat surgery or adverse health outcomes varies. DES is associated with a relatively high probability of follow-up revascularization and a nearly constant probability of negative health outcomes in the short and medium term. In contrast, within three years after a CABG, follow-up reinterventions are rather rare. However, this procedure is particularly associated with an increased risk of mortality and short-term transition into a nursing home.
Identifiants
pubmed: 39268109
doi: 10.21037/jtd-24-251
pii: jtd-16-08-4863
pmc: PMC11388224
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4863-4874Informations de copyright
2024 Journal of Thoracic Disease. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jtd.amegroups.com/article/view/10.21037/jtd-24-251/coif). The authors have no conflicts of interest to declare.
Références
Eur J Cardiovasc Med. 2014 Sep 8;3(1):382-389
pubmed: 25411635
N Engl J Med. 2011 Mar 17;364(11):1016-26
pubmed: 21410370
Circulation. 2017 Oct 3;136(14):1331-1345
pubmed: 28972063
Expert Opin Drug Deliv. 2022 Mar;19(3):269-280
pubmed: 35180832
Am J Cardiol. 2014 Apr 15;113(8):1348-55
pubmed: 24581924
N Engl J Med. 2008 Jan 24;358(4):331-41
pubmed: 18216353
J Am Coll Cardiol. 2015 Sep 29;66(13):1417-27
pubmed: 26403338
N Engl J Med. 2019 Nov 7;381(19):1820-1830
pubmed: 31562798
Int J Cardiol Heart Vasc. 2023 Feb 26;46:101185
pubmed: 37255858
J Geriatr Cardiol. 2018 Feb;15(2):162-172
pubmed: 29662510
Circulation. 2022 Jan 18;145(3):e18-e114
pubmed: 34882435
Health Qual Life Outcomes. 2006 Aug 13;4:49
pubmed: 16904010
Eur Heart J. 2020 Sep 7;41(34):3228-3235
pubmed: 32118272
N Engl J Med. 2012 Apr 19;366(16):1467-76
pubmed: 22452338
Lancet. 2018 Mar 10;391(10124):939-948
pubmed: 29478841
N Engl J Med. 2008 Apr 24;358(17):1781-92
pubmed: 18378517
Circulation. 2013 Apr 23;127(16):1656-63
pubmed: 23532630
J Cardiovasc Surg (Torino). 2012 Oct;53(5):641-50
pubmed: 22252542
Curr Probl Cardiol. 2023 Jul;48(7):101699
pubmed: 36921648
J Cardiothorac Surg. 2022 Oct 1;17(1):246
pubmed: 36183091
Cardiovasc Interv Ther. 2021 Apr;36(2):158-168
pubmed: 33439454
JACC Cardiovasc Interv. 2023 Feb 13;16(3):303-313
pubmed: 36792254
J Cell Physiol. 2019 Aug;234(10):16812-16823
pubmed: 30790284
Am J Cardiol. 2017 Jan 15;119(2):197-202
pubmed: 27817795
Curr Opin Cardiol. 2017 Nov;32(6):707-714
pubmed: 28834794
Catheter Cardiovasc Interv. 2021 Sep;98(3):447-457
pubmed: 32865856
Eur Heart J. 2006 Mar;27(6):671-8
pubmed: 16423872
Ann Thorac Surg. 2009 May;87(5):1386-91
pubmed: 19379870
J Thorac Dis. 2018 Mar;10(3):1960-1967
pubmed: 29707352
Int J Epidemiol. 2014 Jun;43(3):962-70
pubmed: 24603316
J Control Release. 2012 Jul 20;161(2):703-12
pubmed: 22366546
Eur Heart J. 2023 Aug 7;44(30):2833-2842
pubmed: 37288564
Cureus. 2022 Jun 6;14(6):e25687
pubmed: 35812562
Front Cardiovasc Med. 2022 Aug 24;9:977747
pubmed: 36093147