Associations with early vomiting when using intranasal fentanyl and nitrous oxide for procedural sedation in children: A secondary analysis of a randomised controlled trial.
fentanyl
nitrous oxide
ondansetron
procedural sedation
vomiting
Journal
Emergency medicine Australasia : EMA
ISSN: 1742-6723
Titre abrégé: Emerg Med Australas
Pays: Australia
ID NLM: 101199824
Informations de publication
Date de publication:
13 Sep 2024
13 Sep 2024
Historique:
revised:
19
08
2024
received:
18
01
2024
accepted:
20
08
2024
medline:
15
9
2024
pubmed:
15
9
2024
entrez:
13
9
2024
Statut:
aheadofprint
Résumé
Intranasal (IN) fentanyl and nitrous oxide (N This was a planned secondary analysis of a randomised controlled trial comparing the effect of oral ondansetron versus placebo at a single paediatric hospital. Children aged 3 to <18 years with planned procedural sedation with IN fentanyl and N Participants were recruited between October 2016 and January 2019 and 62 out of 436 (14%) had early vomiting. The risk of early vomiting was 30% higher with higher total dose of fentanyl, risk ratio = 1.3 (95% confidence interval = 1.004-1.59). There was little evidence of a relationship between the occurrence of early vomiting and sex, age, weight, type of procedure, fasting duration, time between fentanyl administration and start of procedure, and procedure duration. We found that higher doses of IN fentanyl were associated with higher risk of early vomiting when administered with N
Identifiants
pubmed: 39268662
doi: 10.1111/1742-6723.14497
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Health and Medical Research Council
ID : GNT1171228
Organisme : National Health and Medical Research Council - Investigator Grant
Organisme : Melbourne Campus Clinician Scientist Fellowship
Organisme : Murdoch Children's Research Institute
Informations de copyright
© 2024 The Author(s). Emergency Medicine Australasia published by John Wiley & Sons Australia, Ltd on behalf of Australasian College for Emergency Medicine.
Références
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