Study on the Recombinant Human Interferon α1b, α2b, and Gamma Transient Expression and


Journal

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
ISSN: 1557-7465
Titre abrégé: J Interferon Cytokine Res
Pays: United States
ID NLM: 9507088

Informations de publication

Date de publication:
Oct 2024
Historique:
medline: 10 10 2024
pubmed: 13 9 2024
entrez: 13 9 2024
Statut: ppublish

Résumé

Interferons (IFNs) are universally acknowledged for their pivotal role in antiviral and anticancer responses. Thus, the primary aim of our study was to explore the expressions of IFN-α1b, α2b, and gamma in tobacco leaves via agrobacterium-mediated transient transformation and investigate their possible activities. Briefly, fusion with green fluorescent protein tags aided in detecting the expressed IFN proteins in the foliar tissues. The genetic constructs encoding these fusion proteins were inserted into the MagnICON plant transient expression vector, followed by transformation into the

Identifiants

pubmed: 39269813
doi: 10.1089/jir.2024.0107
doi:

Substances chimiques

Interferon-alpha 0
Antiviral Agents 0
Interferon-gamma 82115-62-6
Interferon alpha-2 0
Recombinant Proteins 0
Recombinant Fusion Proteins 0
Interferon-alpha2b 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

467-475

Auteurs

Dan Xie (D)

Medical College, Guizhou University, Guiyang, China.

Linggai Cao (L)

Molecular Genetics Key Laboratory of China Tobacco, Guizhou Academy of Tobacco Science, Guiyang, China.

Min Guo (M)

Medical College, Guizhou University, Guiyang, China.

Lei Wang (L)

Medical College, Guizhou University, Guiyang, China.

Xiaoliang Zhang (X)

Molecular Genetics Key Laboratory of China Tobacco, Guizhou Academy of Tobacco Science, Guiyang, China.

Shengwen Huang (S)

Prenatal Diagnostic Center, Guizhou provincial people's hospital, Guiyang, China.

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Classifications MeSH